Search Results - "Nemec, Kelsey M."
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Fragile X related protein 1 (FXR1P) regulates proliferation of adult neural stem cells
Published in Human molecular genetics (01-04-2017)“…Fragile X related protein 1 (FXR1P) is a member of the fragile X family of RNA-binding proteins, which includes FMRP and FXR2P. Both FMRP and FXR2P regulate…”
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The enteric nervous system relays psychological stress to intestinal inflammation
Published in Cell (22-06-2023)“…Mental health profoundly impacts inflammatory responses in the body. This is particularly apparent in inflammatory bowel disease (IBD), in which psychological…”
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Engineering an inhibitor-resistant human CSF1R variant for microglia replacement
Published in The Journal of experimental medicine (06-03-2023)“…Hematopoietic stem cell transplantation (HSCT) can replace endogenous microglia with circulation-derived macrophages but has high mortality. To mitigate the…”
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Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism
Published in Neuron (Cambridge, Mass.) (04-09-2024)“…Microglia, the resident immune cells of the central nervous system, are intimately involved in the brain's most basic processes, from pruning neural synapses…”
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Inflammation Drives MicroRNAs to Limit Hepatocyte Bile Acid Transport in Murine Biliary Atresia
Published in The Journal of surgical research (01-12-2020)“…Biliary atresia (BA) is an inflammatory pediatric cholangiopathy with only surgical means for treatment. Many contributors to bile acid synthesis and transport…”
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