Search Results - "Nemazee, David A"

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes by Nemazee, David A, Bürki, Kurt

“…B lymphocytes can be rendered specifically unresponsive to antigen by experimental manipulation in vivo and in vitro, but it remains unclear whether or not…”
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Immune complexes can trigger specific, T cell-dependent, autoanti-IgG antibody production in mice by NEMAZEE, D. A

“…Immunization of mice with a combination of passively administered syngeneic IgG (anti-p-azophenylarsonate [anti-Ars]) antibody and a soluble, multivalent form…”
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Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors): a structural explanation for the high frequency of IgM anti-IgG B cells by SHLOMCHIK, M. J, NEMAZEE, D. A, SATO, V. L, VAN SNICK, J, CARSON, D. A, WEIGERT, M. G

“…The nucleotide sequences of heavy and light chains from 10 monoclonal IgM anti-IgG1 (RF) antibodies were determined and reported here as translated amino acid…”
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Induction of rheumatoid antibodies in the mouse. Regulated production of autoantibody in the secondary humoral response by NEMAZEE, D. A, SATO, V. L

“…A/J mice were found to produce autoreactive IgM anti-IgG1 in response to secondary immunization with a number of protein antigens. No anti-IgG1 was produced…”
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The lymphoproliferating cells of MRL-lpr/lpr mice are a polyclonal population that bear the T lymphocyte receptor for antigen by Nemazee, D A, Studer, S, Steinmetz, M, Dembić, Z, Kiefer, M

“…Mice bearing the recessive gene lpr develop an age-dependent, massive lymphoproliferation, primarily in the lymph nodes (LN), with associated autoimmunity. LN…”
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