Search Results - "Nemani, Krishnamurthy V."
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The Diaphragms of Fenestrated Endothelia: Gatekeepers of Vascular Permeability and Blood Composition
Published in Developmental cell (11-12-2012)“…Fenestral and stomatal diaphragms are endothelial subcellular structures of unknown function that form on organelles implicated in vascular permeability:…”
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Early postnatal exposure to intermittent hypoxia in rodents is proinflammatory, impairs white matter integrity, and alters brain metabolism
Published in Pediatric research (01-07-2017)“…Background Preterm infants are frequently exposed to intermittent hypoxia (IH) associated with apnea and periodic breathing that may result in inflammation and…”
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Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1
Published in Toxicology and applied pharmacology (01-06-2016)“…Obesity is an increasingly urgent global problem, yet, little is known about its causes and less is known how obesity can be effectively treated. We showed…”
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Magnetic nanoparticle hyperthermia induced cytosine deaminase expression in microencapsulated E. coli for enzyme–prodrug therapy
Published in Journal of biotechnology (10-06-2015)“…Engineered bacterial cells that are designed to express therapeutic enzymes under the transcriptional control of remotely inducible promoters can mediate the…”
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Toward Localized In Vivo Biomarker Concentration Measurements
Published in IEEE transactions on magnetics (01-02-2015)“…We know a great deal about the biochemistry of cells because they can be isolated and studied. The biochemistry of the much more complex in vivo environment is…”
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In vitro and in vivo evaluation of SU-8 biocompatibility
Published in Materials Science & Engineering C (01-10-2013)“…SU-8 negative photoresist is a high tensile strength polymer that has been used for a number of biomedical applications that include cell encapsulation and…”
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Effect of alginate microencapsulation on the catalytic efficiency and in vitro enzyme-prodrug therapeutic efficacy of cytosine deaminase and of recombinant E. coli expressing cytosine deaminase
Published in Journal of microencapsulation (02-01-2016)“…Cytosine deaminase (CD) catalyses the enzymatic conversion of the non-toxic prodrug 5-fluorocytosine (5-FC) to the potent chemotherapeutic form, 5-fluorouracil…”
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Isolation and characterization of luciferase from Indian firefly, Luciola praeusta
Published in Luminescence (Chichester, England) (01-02-2014)“…ABSTRACT Luciferase from Indian firefly Luciola praeusta (Coleoptera: Lampyridae: Luciolinae) was isolated and the properties compared with that of the North…”
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Obesity and fatty liver are prevented by inhibition of the aryl hydrocarbon receptor in both female and male mice
Published in Nutrition research (New York, N.Y.) (01-08-2017)“…Inhibition of the aryl hydrocarbon receptor (AHR) prevents Western diet–induced obesity and fatty liver in C57Bl/6J (B6) male mice. The AHR is a…”
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Advances in alginate gel microencapsulation of therapeutic cells
Published in Critical reviews in biomedical engineering (2013)“…Rapid developments in the therapeutic applications of genetically engineered cells and stem cell research have increased the possibilities of addressing some…”
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Early post-natal exposure to intermittent hypoxia in rodents is pro-inflammatory, impairs white matter integrity and alters brain metabolism
Published in Pediatric research (03-05-2017)Get full text
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