Search Results - "Nema, Sandeep"

Protein aggregation—Pathways and influencing factors by Wang, Wei, Nema, Sandeep, Teagarden, Dirk

“…Proteins generally will tend to aggregate under a variety of environmental conditions in comparison with small drug molecules. The extent of aggregation is…”
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Antibody structure, instability, and formulation by Wang, Wei, Singh, Satish, Zeng, David L, King, Kevin, Nema, Sandeep

“…The number of therapeutic monoclonal antibody in development has increased tremendously over the last several years and this trend continues. At present there…”
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Letter regarding ‘Results after treatment of congenital radioulnar synostosis: a systematic review and pooled data analysis’ by Austine, Jose, Nema, Sandeep K.

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Immunogenicity of protein aggregates—Concerns and realities by Wang, Wei, Singh, Satish K., Li, Ning, Toler, Maria R., King, Kevin R., Nema, Sandeep

“…Protein aggregation is one of the key challenges in the development of protein biotherapeutics. It is a critical product quality issue as well as a potential…”
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Ultrasound-guided manipulation does not prevent malalignment over landmark-based fracture reduction in distal radius fracture (Colles) by Nema, Sandeep, Austine, Jose, Ramasubramani, Premkumar, Agrawal, Ruchin

“…Introduction: This systematic review aims to determine the relative risk of distal radius (Colles) fracture (DRF) malalignment between ultrasound (USG)-guided…”
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Clinical and Sonographic Evaluation of Percutaneous Achilles Tendon Tenotomy in Idiopathic Clubfoot: A Prospective Study by Patil, Naveenkumar, Menon, Jagdish, Nema, Sandeep

“…Objectives: Idiopathic Congenital Talipes Equino Varus (CTEV), commonly referred to as Clubfoot, is a complex musculoskeletal deformity affecting infants. The…”
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Do patients with oral squamous cell carcinoma express receptor tyrosine kinase-like orphan receptor 1? Results of an observational study by Nema, Swati, Kallianpur, Shreenivas, Kumar, Ashok, Nema, Rajeev, Vishwakarma, Supriya, Nema, Sandeep

“…Context: The receptor tyrosine kinase-like orphan receptor 1 (ROR1) is a transmembrane protein of the receptor tyrosine kinase family. The expression of ROR1…”
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Clinical and laboratory profile in confirmed vs. suspected septic arthritis patients and its relevance in decision making: A comparative cross-sectional study by Nema, Sandeep K., Basel, Suman Kumar, Austine, Jose, Mirza, Kiyana

“…There were 10%–30% of patients with adult-onset septic arthritis (SA) exhibiting sterile synovial fluid (SF), and the uncertainty in the determining diagnosis…”
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Radiologic assessment of femoral and tibial tunnel placement based on anatomic landmarks in arthroscopic single bundle anterior cruciate ligament reconstruction by Nema, Sandeep Kumar, Balaji, Gopisankar, Akkilagunta, Sujiv, Menon, Jagdish, Poduval, Murali, Patro, Dilip

“…Background: Accurate tibial and femoral tunnel placement has a significant effect on outcomes after anterior cruciate ligament reconstruction (ACLR)…”
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Ceftriaxone concentration at the surgical site following systemic and isolated upper limb injection by Kundra, Pankaj, Vaithilingam, Balaji, Vinayagam, Stalin, Adithan, Chandrasekaran, Nema, Sandeep

“…Background and Aims: This study was conducted to find out the equipotent dose of isolated upper limb injection of ceftriaxone in the upper limb (IUL) surgeries…”
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Does age, time since injury and meniscal injury affect short term functional outcomes in arthroscopic single bundle anterior cruciate ligament reconstruction? by Biswal, Udit Kumar, Balaji, Gopisankar, Nema, Sandeep, Menon, Jagdish, Patro, Dilip Kumar

“…We conducted this study to correlate the short term clinical outcomes after anterior cruciate ligament (ACL) reconstruction with patients' age, time since…”
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Application of high-frequency rheology measurements for analyzing protein-protein interactions in high protein concentration solutions using a model monoclonal antibody (IgG2) by Saluja, Atul, Badkar, Advait V, Zeng, David L, Nema, Sandeep, Kalonia, Devendra S

“…The purpose of this work was to explore the utilization of high-frequency rheology analysis for assessing protein-protein interactions in high protein…”
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Latarjet operation carries three times the risk of failure in seizure versus non-seizure recurrent anterior dislocation of the shoulder joint: outcome of a systematic review with meta-analysis by Rai, Alok, Chouhan, Dushyant, Nema, Sandeep Kumar, Madegowda, Arkesh, Narayan, Rudra, Kar, Bikram K.

“…Background Recurrent anterior shoulder dislocation (RASD) in cases of seizure disorders (SDs) total 50%–80% of all SD-associated shoulder instabilities. Based…”
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A unique case of non- traumatic asymmetric shoulder dislocation with four-part fractures of proximal humeri following seizures by Nema, Sandeep, Pai, Dinker, Sinha, Nirmal, Gupta, Krishna

“…[...]both shoulder dislocations were associated with four-part fracture of proximal humeri, which has not been reported so far…”
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Congenital Humeroradial Synostosis: A Case Report by Nema, Sandeep, Vyas, GS, Sirsikar, Ashish, Bhoj, Praveen K

“…We present here a unique case of humeroradial synostosis. These anomalies are due to longitudinal failure of differentiation. Approximately 150 cases of…”
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In vitro transdermal delivery of therapeutic antibodies using maltose microneedles by Li, Guohua, Badkar, Advait, Nema, Sandeep, Kolli, Chandra Sekhar, Banga, Ajay K.

“…This paper investigates the microneedle-mediated in vitro transdermal delivery of human IgG as a model protein and demonstrates its applicability to deliver a…”
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Critical considerations for developing nucleic acid macromolecule based drug products by Muralidhara, Bilikallahalli K., Baid, Rinku, Bishop, Steve M., Huang, Min, Wang, Wei, Nema, Sandeep

“…•Increased emphasis in recent years on DNA/mRNA macromolecule-based therapeutic drugs.•Formulation excipients and their role in increasing the drug product…”
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Anatomical acromioclavicular joint reconstruction with conventional ACL tightrope: A novel technique by Nema, Sandeep K., Austine, Jose, Uppin, Deepak

“…The management of Acromioclavicular (AC) joint disruptions types IV, V and VI is operative. Over 60 procedures have been described for AC joint reconstruction…”
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Open reduction for hip dislocation in children with arthrogryposis multiplex congenital: Outcomes of a systematic review by Nema, Sandeep Kumar, Arkesh, Chouhan, Dushyant, Austine, Jose, Hs, Mosharaf, Mellipeddi, Ranjith

“…The incidence of hip dislocation (HD) in arthrogryposis multiplex congenital ranges from 15 to 30 %. Besides a stable hip, the ambulation potential of an AMC…”
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MRI Features and Treatment for Idiopathic Chondrolysis of the Hip (ICH) in Children: Outcomes of a Systematic Review by Nema, Sandeep Kumar, Ramasubramani, Premkumar, Austine, Jose, Karunakaran, Govind, Reddy, Vendoti Nitheesha, Reddy, Vendoti Midhusha

“…Background The purpose of this paper was to review the MRI features and treatment for idiopathic chondrolysis of the hip (ICH) in patients aged 18 years or…”
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