Search Results - "Nelson, Wyatt C."

Zeta potential and electroosmotic mobility in microfluidic devices fabricated from hydrophobic polymers: 1. The origins of charge by Tandon, Vishal, Bhagavatula, Sharath K, Nelson, Wyatt C, Kirby, Brian J

“…This paper combines new experimental data for electrokinetic characterization of hydrophobic polymers with a detailed discussion of the putative origins of…”
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Mutations in viral nucleocapsid protein and endoRNase are discovered to associate with COVID19 hospitalization risk by Zhao, Lue Ping, Roychoudhury, Pavitra, Gilbert, Peter, Schiffer, Joshua, Lybrand, Terry P., Payne, Thomas H., Randhawa, April, Thiebaud, Sara, Mills, Margaret, Greninger, Alex, Pyo, Chul-Woo, Wang, Ruihan, Li, Renyu, Thomas, Alexander, Norris, Brandon, Nelson, Wyatt C., Jerome, Keith R., Geraghty, Daniel E.

“…SARS-CoV-2 is spreading worldwide with continuously evolving variants, some of which occur in the Spike protein and appear to increase viral transmissibility…”
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Genotyping of canine MHC gene DLA‐88 by next‐generation sequencing reveals high frequencies of new allele discovery and gene duplication by Pyo, Chul‐Woo, Harkey, Michael A., Torok‐Storb, Beverly, Storb, Rainer, Wang, Ruihan, Thomas, Alexander S., Nelson, Wyatt C., Geraghty, Daniel E.

“…Dogs have served as one of the most reliable preclinical models for a variety of diseases and treatments, including stem/progenitor cell transplantation. At…”
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Dynamic Contact Angles and Hysteresis under Electrowetting-on-Dielectric by Nelson, Wyatt C, Sen, Prosenjit, Kim, Chang-Jin “CJ”

“…By designing and implementing a new experimental method, we have measured the dynamic advancing and receding contact angles and the resulting hysteresis of…”
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Author Correction: Mutations in viral nucleocapsid protein and endoRNase are discovered to associate with COVID19 hospitalization risk by Zhao, Lue Ping, Roychoudhury, Pavitra, Gilbert, Peter, Schiffer, Joshua, Lybrand, Terry P., Payne, Thomas H., Randhawa, April, Thiebaud, Sara, Mills, Margaret, Greninger, Alex, Pyo, Chul-Woo, Wang, Ruihan, Li, Renyu, Thomas, Alexander, Norris, Brandon, Nelson, Wyatt C., Jerome, Keith R., Geraghty, Daniel E.

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The KAG motif of HLA-DRB1 (β71, β74, β86) predicts seroconversion and development of type 1 diabetes by Zhao, Lue Ping, Papadopoulos, George K, Lybrand, Terry P., Moustakas, Antonis K., Bondinas, George P., Carlsson, Annelie, Larsson, Helena Elding, Ludvigsson, Johnny, Marcus, Claude, Persson, Martina, Samuelsson, Ulf, Wang, Ruihan, Pyo, Chul-Woo, Nelson, Wyatt C., Geraghty, Daniel E., Rich, Stephen S., Lernmark, Åke

“…HLA-DR4, a common antigen of HLA-DRB1, has multiple subtypes that are strongly associated with risk of type 1 diabetes (T1D); however, some are risk neutral or…”
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Droplet Actuation by Electrowetting-on-Dielectric (EWOD): A Review by Nelson, Wyatt C., Kim, Chang-Jin 'CJ'

“…This paper reviews publications that have fortified our understanding of the electrowetting-on-dielectric (EWOD) actuation mechanism. Over the last decade,…”
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Oral Insulin Delay of Stage 3 Type 1 Diabetes Revisited in HLA DR4-DQ8 Participants in the TrialNet Oral Insulin Prevention Trial (TN07) by Zhao, Lue Ping, Papadopoulos, George K, Skyler, Jay S, Parikh, Hemang M, Kwok, William W, Bondinas, George P, Moustakas, Antonis K, Wang, Ruihan, Pyo, Chul-Woo, Nelson, Wyatt C, Geraghty, Daniel E, Lernmark, Åke

“…To explore if oral insulin could delay onset of stage 3 type 1 diabetes (T1D) among patients with stage 1/2 who carry HLA DR4-DQ8 and/or have elevated levels…”
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HLA Class II (DR, DQ, DP) Genes Were Separately Associated With the Progression From Seroconversion to Onset of Type 1 Diabetes Among Participants in Two Diabetes Prevention Trials (DPT-1 and TN07) by Zhao, Lue Ping, Papadopoulos, George K, Skyler, Jay S, Pugliese, Alberto, Parikh, Hemang M, Kwok, William W, Lybrand, Terry P, Bondinas, George P, Moustakas, Antonis K, Wang, Ruihan, Pyo, Chul-Woo, Nelson, Wyatt C, Geraghty, Daniel E, Lernmark, Åke

“…To explore associations of HLA class II genes (HLAII) with the progression of islet autoimmunity from asymptomatic to symptomatic type 1 diabetes (T1D)…”
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Progression to type 1 diabetes in the DPT-1 and TN07 clinical trials is critically associated with specific residues in HLA-DQA1-B1 heterodimers by Zhao, Lue Ping, Papadopoulos, George K., Skyler, Jay S., Pugliese, Alberto, Parikh, Hemang M., Kwok, William W., Lybrand, Terry P., Bondinas, George P., Moustakas, Antonis K., Wang, Ruihan, Pyo, Chul-Woo, Nelson, Wyatt C., Geraghty, Daniel E., Lernmark, Åke

“…Aims/hypothesis The aim of this work was to explore molecular amino acids (AAs) and related structures of HLA-DQA1-DQB1 that underlie its contribution to the…”
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Identification of the Novel HLA-A24:518N Null Allele and Evaluation of its Cell Surface Expression on Lymphocytes by Peton, Benjamin P., Taniguchi, Michiko, Garcia-Gomez, Jean F., Zeng, Bruce, Oki, Arisa, Banuelos, Nubia, Nelson, Wyatt C., Abou-Taleb, Randa, Al Malki, Monzr M., Gendzekhadze, Ketevan

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Association of HLA-DQ Heterodimer Residues -18β and β57 With Progression From Islet Autoimmunity to Diabetes in the Diabetes Prevention Trial-Type 1 by Zhao, Lue Ping, Skyler, Jay, Papadopoulos, George K, Pugliese, Alberto, Najera, James Antonio, Bondinas, George P, Moustakas, Antonis K, Wang, Ruihan, Pyo, Chul-Woo, Nelson, Wyatt C, Geraghty, Daniel E, Lernmark, Åke

“…The purpose was to test the hypothesis that the HLA-DQαβ heterodimer structure is related to the progression of islet autoimmunity from asymptomatic to…”
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An integrated genotyping approach for HLA and other complex genetic systems by Nelson, Wyatt C, Pyo, Chul-Woo, Vogan, David, Wang, Ruihan, Pyon, Yoon-Soo, Hennessey, Carly, Smith, Anajane, Pereira, Shalini, Ishitani, Akiko, Geraghty, Daniel E

“…Abstract Clinical immunogenetics laboratories performing routine sequencing of human leukocyte antigen (HLA) genes in support of hematopoietic cell…”
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Comparison of sequence‐specific oligonucleotide probe vs next generation sequencing for HLA‐A, B, C, DRB1, DRB3/B4/B5, DQA1, DQB1, DPA1, and DPB1 typing: Toward single‐pass high‐resolution HLA typing in support of solid organ and hematopoietic cell transplant programs by Smith, Anajane G., Pereira, Shalini, Jaramillo, Andrés, Stoll, Scott T., Khan, Faisal M., Berka, Noureddine, Mostafa, Ahmed A., Pando, Marcelo J., Usenko, Crystal Y., Bettinotti, Maria P., Pyo, Chul‐Woo, Nelson, Wyatt C., Willis, Amanda, Askar, Medhat, Geraghty, Daniel E.

“…Many clinical laboratories supporting solid organ transplant programs use multiple HLA genotyping technologies, depending on individual laboratory needs…”
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Motifs of Three HLA-DQ Amino Acid Residues (α44, β57, β135) Capture Full Association With the Risk of Type 1 Diabetes in DQ2 and DQ8 Children by Zhao, Lue Ping, Papadopoulos, George K, Kwok, William W, Moustakas, Antonis K, Bondinas, George P, Larsson, Helena Elding, Ludvigsson, Johnny, Marcus, Claude, Samuelsson, Ulf, Wang, Ruihan, Pyo, Chul-Woo, Nelson, Wyatt C, Geraghty, Daniel E, Lernmark, Åke

“…HLA-DQA1 and -DQB1 are strongly associated with type 1 diabetes (T1D), and DQ8.1 and DQ2.5 are major risk haplotypes. Next-generation targeted sequencing of…”
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Next-Generation Sequencing Reveals That HLA-DRB3, -DRB4, and -DRB5 May Be Associated With Islet Autoantibodies and Risk for Childhood Type 1 Diabetes by Zhao, Lue Ping, Alshiekh, Shehab, Zhao, Michael, Carlsson, Annelie, Larsson, Helena Elding, Forsander, Gun, Ivarsson, Sten A, Ludvigsson, Johnny, Kockum, Ingrid, Marcus, Claude, Persson, Martina, Samuelsson, Ulf, Örtqvist, Eva, Pyo, Chul-Woo, Nelson, Wyatt C, Geraghty, Daniel E, Lernmark, Åke

“…The possible contribution of HLA-DRB3, -DRB4, and -DRB5 alleles to type 1 diabetes risk and to insulin autoantibody (IAA), GAD65 (GAD autoantibody [GADA]),…”
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Next-Generation HLA Sequence Analysis Uncovers Seven HLA-DQ Amino Acid Residues and Six Motifs Resistant to Childhood Type 1 Diabetes by Zhao, Lue Ping, Papadopoulos, George K, Kwok, William W, Moustakas, Antonis K, Bondinas, George P, Carlsson, Annelie, Elding Larsson, Helena, Ludvigsson, Johnny, Marcus, Claude, Samuelsson, Ulf, Wang, Ruihan, Pyo, Chul-Woo, Nelson, Wyatt C, Geraghty, Daniel E, Lernmark, Åke

“…HLA-DQA1 and -DQB1 genes have significant and potentially causal associations with autoimmune type 1 diabetes (T1D). To follow up on the earlier analysis on…”
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Eleven Amino Acids of HLA-DRB1 and Fifteen Amino Acids of HLA-DRB3, 4, and 5 Include Potentially Causal Residues Responsible for the Risk of Childhood Type 1 Diabetes by Zhao, Lue Ping, Papadopoulos, George K, Kwok, William W, Xu, Bryan, Kong, Matthew, Moustakas, Antonis K, Bondinas, George P, Carlsson, Annelie, Elding-Larsson, Helena, Ludvigsson, Johnny, Marcus, Claude, Persson, Martina, Samuelsson, Ulf, Wang, Ruihan, Pyo, Chul-Woo, Nelson, Wyatt C, Geraghty, Daniel E, Lernmark, Åke

“…Next-generation targeted sequencing of HLA-DRB1 and HLA-DRB3, -DRB4, and -DRB5 (abbreviated as DRB345) provides high resolution of functional variant positions…”
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Incubated Protein Reduction and Digestion on an Electrowetting-on-Dielectric Digital Microfluidic Chip for MALDI-MS by Nelson, Wyatt C, Peng, Ivory, Lee, Geun-An, Loo, Joseph A, Garrell, Robin L, “CJ” Kim, Chang-Jin

“…Localized heating of droplets on an electrowetting-on-dielectric (EWOD) chip has been implemented and shown to accelerate trypsin digestion reaction rates,…”
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Simultaneous and selective isolation of multiple subpopulations of rare cells from peripheral blood using ensemble-decision aliquot ranking (eDAR) by Zhao, Mengxia, Wei, Bingchuan, Nelson, Wyatt C, Schiro, Perry G, Chiu, Daniel T

“…Rare cells, such as circulating tumor cells (CTCs), can be heterogeneous. The isolation and identification of rare cells with different phenotypes is…”
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