Search Results - "Nelson, TJ"
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1
Pharmacological Modulation of Calcium Homeostasis in Familial Dilated Cardiomyopathy: An In Vitro Analysis From an RBM20 Patient‐Derived iPSC Model
Published in Clinical and translational science (01-06-2016)“…For inherited cardiomyopathies, abnormal sensitivity to intracellular calcium (Ca2+), incurred from genetic mutations, initiates subsequent molecular events…”
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2
Oxidation of Cholesterol by Amyloid Precursor Protein and β-Amyloid Peptide
Published in The Journal of biological chemistry (25-02-2005)“…Alzheimer's disease (AD) is characterized by accumulation of the neurotoxic peptide β-amyloid, which is produced by proteolysis of amyloid precursor protein…”
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3
Low-Income Fathers
Published in Annual review of sociology (01-01-2004)“…This article reviews recent literature on low-income fathers, including the transition to fatherhood for young unmarried fathers and levels of father…”
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4
Gabapentin Use in Pediatric Spinal Fusion Patients: A Randomized, Double-Blind, Controlled Trial
Published in Anesthesia and analgesia (01-05-2010)“…Gabapentin has opioid-sparing effects in adult surgical patients, but no reported studies have involved children and adolescents. In a double-blind,…”
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5
Induced Pluripotent Stem Cells: An Emerging Theranostics Platform
Published in Clinical pharmacology and therapeutics (01-05-2011)“…Nuclear reprogramming generates induced pluripotent stem (iPS) cells endowed with the unlimited potential to reconstruct genetically identical tissues. This…”
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ALERT PRIORITIZATION AND STRENGTHENING: TOWARDS AN INDUSTRY STANDARD PRIORITY SCORING SYSTEM FOR IDS ANALYSTS USING OPEN SOURCE TOOLS AND MODELS OF MACHINE LEARNING
Published in South Dakota law review (22-09-2020)“…Intrusion detection systems ("IDSs") are generating volumes of alert messages around the clock leaving alert response teams with a daunting task: determining…”
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7
Therapeutic Effects of PKC Activators in Alzheimer's Disease Transgenic Mice
Published in Proceedings of the National Academy of Sciences - PNAS (27-07-2004)“…Alzheimer's disease (AD) characteristically presents with early memory loss. Regulation of K+channels, calcium homeostasis, and protein kinase C (PKC)…”
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8
Stem Cells: Biologics for Regeneration
Published in Clinical pharmacology and therapeutics (01-11-2008)“…Degenerative diseases are a growing epidemic. Pharmacotherapy aimed at treating the root cause of these diseases, namely, progressive cell destruction and…”
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9
Protein Synthesis Required for Long-Term Memory Is Induced by PKC Activation on Days before Associative Learning
Published in Proceedings of the National Academy of Sciences - PNAS (08-11-2005)“…Protein synthesis has long been known to be required for associative learning to consolidate into long-term memory. Here we demonstrate that PKC isozyme…”
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10
SRF-dependent gene expression in isolated cardiomyocytes: Regulation of genes involved in cardiac hypertrophy
Published in Journal of molecular and cellular cardiology (01-09-2005)“…Serum response factor (SRF) is a transcription factor required for the regulation of genes important for cardiac structure and function. Notably, the “fetal…”
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11
Insulin and cholesterol pathways in neuronal function, memory and neurodegeneration
Published in Biochemical Society transactions (01-11-2005)“…Insulin and cholesterol play important roles in basic metabolic processes in peripheral tissues. Both insulin and cholesterol can also act as signalling…”
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12
A Prospective Evaluation of Opioid Weaning in Opioid-Dependent Pediatric Critical Care Patients
Published in Anesthesia and analgesia (01-04-2006)“…Critically ill children are treated with opioid medication in an attempt to decrease stress and alleviate pain during prolonged pediatric intensive care. This…”
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13
Predictors of Mortality in Close Proximity Blast Injuries During Operation Iraqi Freedom
Published in Journal of the American College of Surgeons (01-03-2006)“…Blast injury is an increasingly common problem faced by military surgeons in the field. Because of urban terrorism worldwide, blast injury is becoming more…”
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14
Identification and Characterization of a Glycosaminoglycan Recognition Element of the C Chemokine Lymphotactin
Published in The Journal of biological chemistry (26-03-2004)“…Chemokine-mediated recruitment of leukocytes in vivo depends on interactions with cell surface glycosaminoglycans. Lymphotactin, the unique member of the “C”…”
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15
Hippocampal protein-protein interactions in spatial memory
Published in Hippocampus (2004)“…Memory consolidation in mammalian brain is accompanied by widespread reorganization of synaptic contacts and dendritic structure. Understanding of the…”
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16
Time domains of neuronal Ca2+ signaling and associative memory : steps through a calexcitin, ryanodine receptor, K+ channel cascade
Published in Trends in neurosciences (Regular ed.) (01-12-1998)“…Synaptic changes that underlie associative learning and memory begin with temporally related activity of two or more independent synaptic inputs to common…”
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17
Internal Ca2+Mobilization is Altered in Fibroblasts from Patients with Alzheimer Disease
Published in Proceedings of the National Academy of Sciences - PNAS (18-01-1994)“…The recent demonstration of K+channel dysfunction in fibroblasts from Alzheimer disease (AD) patients and past observations of Ca2+-mediated K+channel…”
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18
Conserved Enhancer in the Serum Response Factor Promoter Controls Expression During Early Coronary Vasculogenesis
Published in Circulation research (30-04-2004)“…ABSTRACT—Serum response factor (SRF) is a transcription factor required for mesoderm formation in the developing mouse embryo that is important for myogenic…”
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Alzheimer's-Specific Effects of Soluble β -amyloid on Protein Kinase C-α and -γ Degradation in Human Fibroblasts
Published in Proceedings of the National Academy of Sciences - PNAS (12-05-1998)“…Alzheimer's disease (AD) is a multifactorial disease in which β -amyloid peptide (β AP) plays a critical role. We report here that the soluble fraction 1-40 of…”
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20
Theta Rhythm of Hippocampal CA1 Neuron Activity: Gating by GABAergic Synaptic Depolarization
Published in Journal of neurophysiology (01-01-2001)“…Laboratory of Adaptive Systems, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 Sun, Miao-Kun,…”
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