Search Results - "Nelson, Sydney A."
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Vpr attenuates antiviral immune responses and is critical for full pathogenicity of SIVmac239 in rhesus macaques
Published in iScience (15-12-2023)“…The accessory viral protein R (Vpr) is encoded by all primate lentiviruses. Vpr counteracts DNA repair pathways, modulates viral immune sensing, and induces…”
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Journal Article -
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Systems Analysis Reveals Contraceptive-Induced Alteration of Cervicovaginal Gene Expression in a Randomized Trial
Published in Frontiers in reproductive health (03-03-2022)“…Hormonal contraceptives (HCs) are vital in managing the reproductive health of women. However, HC usage has been linked to perturbations in cervicovaginal…”
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Journal Article -
3
Early T follicular helper cell activity accelerates hepatitis C virus-specific B cell expansion
Published in The Journal of clinical investigation (19-01-2021)“…Early appearance of neutralizing antibodies during acute hepatitis C virus (HCV) infection is associated with spontaneous viral clearance. However, the…”
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4
Systems analysis reveals differential expression of endocervical genes in African women randomized to DMPA-IM, LNG implant or cu-IUD
Published in Clinical immunology (Orlando, Fla.) (01-10-2023)“…Although effective contraceptives are crucial for preventing unintended pregnancies, evidence suggests that their use may perturb the female genital tract…”
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5
Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection
Published in PLoS pathogens (28-06-2021)“…HIV associated immune activation (IA) is associated with increased morbidity in people living with HIV (PLWH) on antiretroviral therapy, and remains a barrier…”
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Journal Article -
6
Vpr attenuates antiviral immune responses and is critical for full pathogenicity of SIV mac239 in rhesus macaques
Published in iScience (15-12-2023)“…The accessory viral protein R (Vpr) is encoded by all primate lentiviruses. Vpr counteracts DNA repair pathways, modulates viral immune sensing, and induces…”
Get full text
Journal Article