Search Results - "Nelson, Shelley"
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Nkx6 Transcription Factors and Ptf1a Function as Antagonistic Lineage Determinants in Multipotent Pancreatic Progenitors
Published in Developmental cell (15-06-2010)“…The molecular mechanisms that underlie cell lineage diversification of multipotent progenitors in the pancreas are virtually unknown. Here we show that the…”
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Predictors of female American black bear body mass in an anthropogenic landscape
Published in The Journal of wildlife management (01-05-2024)“…Anthropogenic pressure, such as urbanization and habitat loss, can wield many effects on wildlife that radiate through ecosystems. Large carnivores tend to…”
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The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting beta-cell fate specification in Pdx1+ pancreatic progenitor cells
Published in Development (Cambridge) (01-07-2007)“…Despite much progress in identifying transcriptional regulators that control the specification of the different pancreatic endocrine cell types, the…”
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Estimates of Southern White-tailed Ptarmigan daily nest survival from multiple sites in the Southern Rocky Mountains of Colorado
Published in Avian conservation and ecology (01-01-2024)“…Estimating vital rates of avian species is important to understand population dynamics and develop potential conservation strategies that target rates for…”
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Religious Economy or Organizational Field? Predicting Bishops' Votes at the Second Vatican Council
Published in American sociological review (01-08-2010)“…This article explores the national factors that predict bishops' votes on two of the most contentious issues at the Second Vatican Council. Using data obtained…”
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NKX6 transcription factor activity is required for alpha- and beta-cell development in the pancreas
Published in Development (Cambridge) (01-07-2005)“…In diabetic individuals, the imbalance in glucose homeostasis is caused by loss or dysfunction of insulin-secreting beta-cells of the pancreatic islets. As…”
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Endodermal expression of Nkx6 genes depends differentially on Pdx1
Published in Developmental biology (15-12-2005)“…Nkx family members are essential for normal development of many different tissues such as the heart, lungs, thyroid, prostate, and CNS. Here, we describe the…”
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School co-ethnicity and Hispanic parental involvement
Published in Social science research (01-09-2012)“…► We model how schools’ Hispanic concentration affects Hispanic parental involvement. ► Immigrant parents are more involved in schools with a greater Hispanic…”
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Visualizing the risk landscape to adaptively increase post-release survival of translocated Galliformes
Published in Frontiers in conservation science (13-08-2024)“…Translocation of captive-bred animals is a widely used conservation strategy to support the recovery of imperiled wild populations. Identifying which factors…”
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TALE Homeodomain Proteins Regulate Gonadotropin-releasing Hormone Gene Expression Independently and via Interactions with Oct-1
Published in The Journal of biological chemistry (16-07-2004)“…Gonadotropin-releasing hormone (GnRH) is the central regulator of reproductive function. Expression of the GnRH gene is confined to a rare population of…”
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Expression of Nkx6 Genes in the Hindbrain and Gut of the Developing Mouse
Published in The journal of histochemistry and cytochemistry (01-06-2005)“…The Nkx6 gene family of homeodomain transcription factors consists of three members. For two, Nkx6.1 and Nkx6.2, important developmental roles in the central…”
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Neuron-Specific Expression in Vivo by Defined Transcription Regulatory Elements of the GnRH Gene
Published in Endocrinology (Philadelphia) (01-04-2002)“…The GnRH-expressing neurons are the ultimate regulator of reproductive function. GnRH gene expression is limited to this small population of neurons in the…”
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Oct-1 Binds Promoter Elements Required for Transcription of the GnRH Gene
Published in Molecular endocrinology (Baltimore, Md.) (01-04-1998)“…The GnRH gene is exclusively expressed in a discrete population of neurons in the hypothalamus. The promoter-proximal 173 bp of the rat GnRH gene are highly…”
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Life history consequences of climate change in hibernating mammals: a review
Published in Ecography (Copenhagen) (01-06-2022)“…Climatic shifts to warmer and often drier conditions are challenging terrestrial species worldwide. These shifts are occurring more rapidly at higher…”
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Neuron-Restricted Expression of the Rat Gonadotropin-Releasing Hormone Gene Is Conferred by a Cell-Specific Protein Complex that Binds Repeated CAATT Elements
Published in Molecular endocrinology (Baltimore, Md.) (01-11-2002)“…GnRH gene expression is restricted to a tiny population of neurons scattered throughout the mediobasal hypothalamus. The combination of a 300-bp enhancer and…”
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Black Bear Fitness and Interactions with Humans in an Anthropogenic Context
Published 01-01-2022“…Multiple studies confirm that anthropogenic pressure has reshaped at least 75% of the global terrestrial biosphere, converting these areas to more…”
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Dissertation -
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Neuron-Specific Expression of the Rat Gonadotropin-Releasing Hormone Gene Is Conferred by Interactions of a Defined Promoter Element with the Enhancer in GT1–7 Cells
Published in Molecular endocrinology (Baltimore, Md.) (01-09-2000)“…Neuroendocrine control of the reproductive cascade is mediated by GnRH, which in mammals is produced by a subset of neurons scattered throughout the…”
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The GnRH promoter: Target of transcription factors, hormones, and signaling pathways
Published in Molecular and cellular endocrinology (25-05-1998)“…Gonadotropin-releasing hormone (GnRH) is essential for normal reproductive maturation and function. We present a review of the known mechanisms of hypothalamic…”
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Ptf1a and Nkx6 transcription factors function as antagonistic lineage determinants in multipotent pancreatic progenitors
Published in Developmental cell (15-06-2010)“…The molecular mechanisms that underlie cell lineage diversification of multipotent progenitors in the pancreas are virtually unknown. Here, we show that the…”
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Journal Article -
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Nkx6 Transcription Factors and Ptf1 a Function as Antagonistic Lineage Determinants in Multipotent Pancreatic Progenitors
Published in Developmental cell (2010)Get full text
Journal Article