Search Results - "Nelson, Sally K."

Candidate blood proteome markers of Alzheimer's disease onset and progression: a systematic review and replication study by Kiddle, Steven J, Sattlecker, Martina, Proitsi, Petroula, Simmons, Andrew, Westman, Eric, Bazenet, Chantal, Nelson, Sally K, Williams, Stephen, Hodges, Angela, Johnston, Caroline, Soininen, Hilkka, Kłoszewska, Iwona, Mecocci, Patrizia, Tsolaki, Magda, Vellas, Bruno, Newhouse, Stephen, Lovestone, Simon, Dobson, Richard J B

“…A blood-based protein biomarker, or set of protein biomarkers, that could predict onset and progression of Alzheimer's disease (AD) would have great utility;…”
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The induction of human superoxide dismutase and catalase in vivo: A fundamentally new approach to antioxidant therapy by Nelson, Sally K., Bose, Swapan K., Grunwald, Gary K., Myhill, Paul, McCord, Joe M.

“…A composition consisting of extracts of five widely studied medicinal plants (Protandim) was administered to healthy human subjects ranging in age from 20 to…”
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Thiol Antioxidants Inhibit the Adjuvant Effects of Aerosolized Diesel Exhaust Particles in a Murine Model for Ovalbumin Sensitization by Whitekus, Michael J, Li, Ning, Zhang, Min, Wang, Meiying, Horwitz, Marcus A, Nelson, Sally K, Horwitz, Lawrence D, Brechun, Nicholas, Diaz-Sanchez, David, Nel, Andre E

“…Although several epidemiological studies indicate a correlation between exposure to ambient particulate matter and adverse health effects in humans, there is…”
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Identification of cis-regulatory variation influencing protein abundance levels in human plasma by Lourdusamy, Anbarasu, Newhouse, Stephan, Lunnon, Katie, Proitsi, Petra, Powell, John, Hodges, Angela, Nelson, Sally K, Stewart, Alex, Williams, Stephen, Kloszewska, Iwona, Mecocci, Patrizia, Soininen, Hilkka, Tsolaki, Magda, Vellas, Bruno, Lovestone, Simon, Dobson, Richard

“…Proteins are central to almost all cellular processes, and dysregulation of expression and function is associated with a range of disorders. A number of…”
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Age-Dependent Changes in the Cerebrospinal Fluid Proteome by Slow Off-Rate Modified Aptamer Array by Baird, Geoffrey S, Nelson, Sally K, Keeney, Tracy R, Stewart, Alex, Williams, Stephen, Kraemer, Stephan, Peskind, Elaine R, Montine, Thomas J

“…An important precondition for the successful development of diagnostic assays of cerebrospinal fluid (CSF) biomarkers of age-related neurodegenerative diseases…”
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Bucillamine, A Thiol Antioxidant, Prevents Transplantation-Associated Reperfusion Injury by Amersi, Farin, Nelson, Sally K., Da Shen, Xiu, Kato, Hirohisa, Melinek, Judy, Kupiec-Weglinski, Jerzy W., Horwitz, Lawrence D., Busuttil, Ronald W., Horwitz, Marcus A.

“…Ischemia/reperfusion (I/R) injury is a serious potential threat to outcomes in organ transplantation and other clinical arenas in which there is temporary…”
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Oxidative stress in organ preservation: a multifaceted approach to cardioplegia by Nelson, Sally K, Bose, Swapan, Rizeq, Mona, McCord, Joe M.

“…Every transplant is a reperfused organ and, therefore, undergoes some degree of oxidative damage. Postischemic reperfusion injury results in non-specific free…”
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A novel heparin-binding, human chimeric, superoxide dismutase improves myocardial preservation and protects from ischemia-reperfusion injury by Nelson, Sally K, Gao, Bifeng, Bose, Swapan, Rizeq, Mona, McCord, Joe M

“…The plasma membranes of endothelial cells are sites of physiologic injury caused by superoxide attack, whether the radicals are generated within the cell…”
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Aptamer-based multiplexed proteomic technology for biomarker discovery by Gold, Larry, Ayers, Deborah, Bertino, Jennifer, Bock, Christopher, Bock, Ashley, Brody, Edward N, Carter, Jeff, Dalby, Andrew B, Eaton, Bruce E, Fitzwater, Tim, Flather, Dylan, Forbes, Ashley, Foreman, Trudi, Fowler, Cate, Gawande, Bharat, Goss, Meredith, Gunn, Magda, Gupta, Shashi, Halladay, Dennis, Heil, Jim, Heilig, Joe, Hicke, Brian, Husar, Gregory, Janjic, Nebojsa, Jarvis, Thale, Jennings, Susan, Katilius, Evaldas, Keeney, Tracy R, Kim, Nancy, Koch, Tad H, Kraemer, Stephan, Kroiss, Luke, Le, Ngan, Levine, Daniel, Lindsey, Wes, Lollo, Bridget, Mayfield, Wes, Mehan, Mike, Mehler, Robert, Nelson, Sally K, Nelson, Michele, Nieuwlandt, Dan, Nikrad, Malti, Ochsner, Urs, Ostroff, Rachel M, Otis, Matt, Parker, Thomas, Pietrasiewicz, Steve, Resnicow, Daniel I, Rohloff, John, Sanders, Glenn, Sattin, Sarah, Schneider, Daniel, Singer, Britta, Stanton, Martin, Sterkel, Alana, Stewart, Alex, Stratford, Suzanne, Vaught, Jonathan D, Vrkljan, Mike, Walker, Jeffrey J, Watrobka, Mike, Waugh, Sheela, Weiss, Allison, Wilcox, Sheri K, Wolfson, Alexey, Wolk, Steven K, Zhang, Chi, Zichi, Dom

“…The interrogation of proteomes ("proteomics") in a highly multiplexed and efficient manner remains a coveted and challenging goal in biology and medicine. We…”
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ALS Biomarker Discovery Using SOMAscan™ Multiplex Proteomic Technology by Nelson, Sally K., Sterling, David, Williams, Stephen, Lawson, Robert J., Berry, James D., Cudkowicz, Merit E

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Advance Access published on May 16, 2012 Identification of cis-regulatory variation influencing protein abundance levels in human plasma by LOURDUSAMY, Anbarasu, NEWHOUSE, Stephan, MECOCCI, Patrizia, SOININEN, Hilkka, TSOLAKI, Magda, VELLAS, Bruno, LOVESTONE, Simon, DOBSON, Richard, LUNNON, Katie, PROITSI, Petra, POWELL, John, HODGES, Angela, NELSON, Sally K, STEWART, Alex, WILLIAMS, Stephen, KLOSZEWSKA, Iwona

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Discovering Signatures of Healthy Brain Aging with Aptamer Proteomic Technology by Nelson, Sally K., Montine, Thomas J., Keeney, Tracy R., Stewart, Alex, Williams, Stephen A., Peskind, Elaine, Baird, Geoffrey S.

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The toxicity of high-dose superoxide dismutase suggests that superoxide can both initiate and terminate lipid peroxidation in the reperfused heart by Nelson, S K, Bose, S K, McCord, J M

“…Recently, we described an anomalous bell-shaped dose-response curve for the protection of the reoxygenated isolated myocardium by superoxide dismutase (SOD)…”
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Tat Protein of Human Immunodeficiency Virus Type 1 Represses Expression of Manganese Superoxide Dismutase in HeLa Cells by Flores, Sonia C., Marecki, John C., Harper, Kimberly P., Bose, Swapan K., Nelson, Sally K., McCord, Joe M.

“…Using a HeLa cell line stably transfected with the tat gene from human immunodeficiency virus type 1, we have found that the expression of the regulatory Tat…”
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A novel iron chelator in combination with a p-selectin antagonist prevents ischemia/reperfusion injury in a rat liver model by AMERSI, Farin, DULKANCHAINUN, Tom, HORWITZ, Marcus A, BUSUTTIL, Ronald W, NELSON, Sally K, FARMER, Douglas G, KATO, Hirohisa, ZAKY, Joseph, MELINEK, Judy, SHAW, Gray D, KUPIEC-WEGLINSKI, Jerzy W, HORWITZ, Lawrence D

“…Hepatic ischemia/reperfusion (I/R) injury is associated with early and late graft failure after liver transplantation. A major mechanism is leukocyte adhesion…”
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Mitochondrial respiration scavenges extramitochondrial superoxide anion via a nonenzymatic mechanism by Guidot, D M, Repine, J E, Kitlowski, A D, Flores, S C, Nelson, S K, Wright, R M, McCord, J M

“…We determined that mitochondrial respiration reduced cytosolic oxidant stress in vivo and scavenged extramitochondrial superoxide anion (O2-.) in vitro. First,…”
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Leukemia inhibitory factor and tumor necrosis factor induce manganese superoxide dismutase and protect rabbit hearts from reperfusion injury by Nelson, Sally K., Wong, Grace H.W., McCord, Joe M.

“…Leukemia inhibitory factor (LIF) and tumor necrosis factor (TNF) have been shown to protect animals from radiation, hyperoxia, and endotoxic shock. TNF is also…”
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BUCILLAMINE, A DIFFUSIBLE ANTIOXIDANT, PREVENTS ISCHEMIA/REPERFUSION INJURY IN AN EX-VIVO RAT LIVER MODEL: Abstract# 328 Poster Board #-Session: P175-I by Amersi, Farin F., Nelson, Sally K., Farmer, Douglas G., Kato, Hirohisa, Melinek, Judy, Zaky, Joseph, Kupiec-Weglinski, Jerzy W., Horwitz, Lawrence D., Busuttil, Ronald W., Horwitz, Marcus A.

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A NOVEL IRON CHELATOR IN COMBINATION WITH A P-SELECTIN ANTAGONIST PREVENTS ISCHEMIA/REPERFUSION INJURY IN A RAT LIVER MODEL1 by Amersi, Farin, Dulkanchainun, Tom, Nelson, Sally K., Farmer, Douglas G., Kato, Hirohisa, Zaky, Joseph, Melinek, Judy, Shaw, Gray D., Kupiec-Weglinski, Jerzy W., Horwitz, Lawrence D., Horwitz, Marcus A., Busuttil, and Ronald W.

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Copper-marginal and copper-deficient diets decrease aortic prostacyclin production and copper-dependent superoxide dismutase activity, and increase aortic lipid peroxidation in rats by Nelson, S K, Huang, C J, Mathias, M M, Allen, K G

“…Agonist challenged aortic prostacyclin production was examined in copper-adequate, -marginal and -deficient rats fed AIN-based diets providing 6.7, 1.7 and 0.8…”
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