Search Results - "Nelson, P. S."

In vitro-transcribed antigen receptor mRNA nanocarriers for transient expression in circulating T cells in vivo by Parayath, N. N., Stephan, S. B., Koehne, A. L., Nelson, P. S., Stephan, M. T.

“…Engineering chimeric antigen receptors (CAR) or T cell receptors (TCR) helps create disease-specific T cells for targeted therapy, but the cost and rigor…”
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HDAC inhibition impedes epithelial–mesenchymal plasticity and suppresses metastatic, castration-resistant prostate cancer by Ruscetti, M, Dadashian, E L, Guo, W, Quach, B, Mulholland, D J, Park, J W, Tran, L M, Kobayashi, N, Bianchi-Frias, D, Xing, Y, Nelson, P S, Wu, H

“…PI3K (phosphoinositide 3-kinase)/AKT and RAS/MAPK (mitogen-activated protein kinase) pathway coactivation in the prostate epithelium promotes both…”
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androgen-regulated type II serine protease TMPRSS2 is differentially expressed and mislocalized in prostate adenocarcinoma by Lucas, JM, True, L, Hawley, S, Matsumura, M, Morrissey, C, Vessella, R, Nelson, PS

“…Transmembrane serine protease 2 (TMPRSS2) is an androgen-regulated member of the type two transmembrane protease (TTSP) family. Two other members of the TTSP…”
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IL-6 promotes prostate tumorigenesis and progression through autocrine cross-activation of IGF-IR by Rojas, A, Liu, G, Coleman, I, Nelson, P S, Zhang, M, Dash, R, Fisher, P B, Plymate, S R, Wu, J D

“…As an established mediator of inflammation, interleukin-6 (IL-6) is implicated to facilitate prostate cancer progression to androgen independence through…”
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Profiling influences of senescent and aged fibroblasts on prostate carcinogenesis by Dean, J P, Nelson, P S

“…Experimental evidence suggests that ageing-associated alterations in the tissue microenvironment act to promote prostate carcinogenesis. In this review, we…”
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EPLIN downregulation promotes epithelial-mesenchymal transition in prostate cancer cells and correlates with clinical lymph node metastasis by Zhang, S, Wang, X, Osunkoya, A O, Iqbal, S, Wang, Y, Chen, Z, Müller, S, Chen, Z, Josson, S, Coleman, I M, Nelson, P S, Wang, Y A, Wang, R, Shin, D M, Marshall, F F, Kucuk, O, Chung, L W K, Zhau, H E, Wu, D

“…Epithelial–mesenchymal transition (EMT) is a crucial mechanism for the acquisition of migratory and invasive capabilities by epithelial cancer cells. By…”
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Use of Aspirin and Other Nonsteroidal Antiinflammatory Medications in Relation to Prostate Cancer Risk by Salinas, Claudia A., Kwon, Erika M., FitzGerald, Liesel M., Feng, Ziding, Nelson, Peter S., Ostrander, Elaine A., Peters, Ulrike, Stanford, Janet L.

“…Recent interest has focused on the role that inflammation may play in the development of prostate cancer and whether use of aspirin or other nonsteroidal…”
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A fully degradable tracheal stent: In vitro and in vivo characterization of material degradation by Ng, Anthony H. C., Ng, Nelson S. P., Zhu, G. H., Lim, Lynne H. Y., Venkatraman, Subbu S.

“…We report on the testing of materials for a fully degradable tracheal stent. Such a stent has several advantages over currently used permanent stents made of…”
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Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2 by BIAOYANG LIN, FERGUSON, C, WHITE, J. T, SHUNYOU WANG, VESSELLA, R, TRUE, L. D, HOOD, L, NELSON, P. S

“…Genes regulated by androgenic hormones are of critical importance for the normal physiological function of the human prostate gland, and they contribute to the…”
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Characterization of hK4 (Prostase), a Prostate-Specific Serine Protease:  Activation of the Precursor of Prostate Specific Antigen (pro-PSA) and Single-Chain Urokinase-Type Plasminogen Activator and Degradation of Prostatic Acid Phosphatase by Takayama, Thomas K, McMullen, Brad A, Nelson, Peter S, Matsumura, Masazumi, Fujikawa, Kazuo

“…hK4 (prostase, KLK4), a recently cloned prostate-specific serine protease and a member of the tissue kallikrein family, is a zymogen composed of 228 amino acid…”
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Toll receptors: an expanding role in our understanding of human disease by Schuster, James M., Nelson, Peter S.

“…Toll receptor proteins in Drosophila are involved in establishing the dorsal‐ventral axis in embryogenesis as well as participating in the innate immune…”
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Determining Cause of Death in Prostate Cancer: Are Death Certificates Valid? by Penson, David F., Albertsen, Peter C., Nelson, Peter S., Barry, Michael, Stanford, Janet L.

“…U.S. Department of Health andHuman Services,2000.(3) Office of Health Statistics,Research andTechnology,National Center for Health Statistics. Instruction…”
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New nomenclature for the human tissue kallikrein gene family by DIAMANDIS, Eleftherios P, YOUSEF, George M, STENMAN, Ulf-Hakan, RITTENHOUSE, Harry G, WAIN, Hester, CLEMENTS, Judith, ASHWORTH, Linda K, YOSHIDA, Shigetaka, EGELRUD, Torbjorn, NELSON, Peter S, SHIOSAKA, Sadao, LITTLE, Sheila, LILJA, Hans

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Histopathology of the liver in children with chronic hepatitis C viral infection by Badizadegan, Kamran, Jonas, Maureen M., Ott, Mary Jane, Nelson, Suzanne P., Perez‐Atayde, Antonio R.

“…Although the epidemiology, natural history, and pathological aspects of chronic hepatitis C are well‐defined in the adult population, little is known about the…”
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The comparative effectiveness of rosuvastatin vs. other statins in patients with an increased risk of failure to reach NCEP ATP III goal by Harley, C R, Gandhi, S, Heien, H, Nelson, S P

“…Previous studies have demonstrated that failure to reach National Cholesterol Education Program (NCEP) target low-density lipoprotein cholesterol (LDL-C) goal…”
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The human (PEDB) and mouse (mPEDB) Prostate Expression Databases by Nelson, Peter S, Pritchard, Colin, Abbott, Denise, Clegg, Nigel

“…The Prostate Expression Databases (PEDB and mPEDB) are online resources designed to allow researchers to access and analyze gene expression information derived…”
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Systematic and functional characterization of novel androgen receptor variants arising from alternative splicing in the ligand-binding domain by Uo, T, Dvinge, H, Sprenger, C C, Bradley, R K, Nelson, P S, Plymate, S R

“…The presence of intact ligand-binding domain (LBD) ensures the strict androgen-dependent regulation of androgen receptor (AR): binding of androgen induces…”
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PART-1 : A novel human prostate-specific, androgen-regulated gene that maps to chromosome 5q12 by BIAOYANG LIN, WHITE, J. T, FERGUSON, C, BUMGARNER, R, FRIEDMAN, C, TRASK, B, ELLIS, W, LANGE, P, HOOD, L, NELSON, P. S

“…Genes regulated by androgenic hormones are of critical importance for the normal physiological function of the human prostate gland, and they contribute to the…”
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Integrative molecular profiling of routine clinical prostate cancer specimens by Grasso, C.S., Cani, A.K., Hovelson, D.H., Quist, M.J., Douville, N.J., Yadati, V., Amin, A.M., Nelson, P.S., Betz, B.L., Liu, C-J., Knudsen, K.E., Cooney, K.A., Feng, F.Y., McDaniel, A.S., Tomlins, S.A.

“…Comprehensive molecular profiling led to the recognition of multiple prostate cancer (PCa) molecular subtypes and driving alterations, but translating these…”
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Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015 by Gillessen, S., Omlin, A., Attard, G., de Bono, J.S., Efstathiou, E., Fizazi, K., Halabi, S., Nelson, P.S., Sartor, O., Smith, M.R., Soule, H.R., Akaza, H., Beer, T.M., Beltran, H., Chinnaiyan, A.M., Daugaard, G., Davis, I.D., De Santis, M., Drake, C.G., Eeles, R.A., Fanti, S., Gleave, M.E., Heidenreich, A., Hussain, M., James, N.D., Lecouvet, F.E., Logothetis, C.J., Mastris, K., Nilsson, S., Oh, W.K., Olmos, D., Padhani, A.R., Parker, C., Rubin, M.A., Schalken, J.A., Scher, H.I., Sella, A., Shore, N.D., Small, E.J., Sternberg, C.N., Suzuki, H., Sweeney, C.J., Tannock, I.F., Tombal, B.

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