Search Results - "Nelson, Norman C."

Simultaneous Detection of Multiple Nucleic Acid Targets in a Homogeneous Format by Nelson, Norman C, Cheikh, Azzouz Ben, Matsuda, Eiji, Becker, Michael M

“…The acridinium ester 4-(2-succinimidyloxycarbonylethyl)phenyl-10-methylacridinium 9-carboxylate trifluoromethane sulfonate (AE), which reacts rapidly with…”
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The Double Helix Is Dehydrated:  Evidence from the Hydrolysis of Acridinium Ester-Labeled Probes by Becker, Michael, Lerum, Vicente, Dickson, Steve, Nelson, Norman C, Matsuda, Eiji

“…A highly chemiluminescent reporter molecule, acridinium ester (AE), was tethered to single-stranded oligonucleotide probes and hybridized to complementary as…”
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Surgical removal of subfoveal iatrogenic choroidal neovascular membranes by Chen, C J, Urban, L L, Nelson, N C, Fratkin, J D

“…To present the cases of two patients with laser-induced iatrogenic subfoveal choroidal neovascular membranes (CNVMs) who underwent surgical removal of the…”
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Advantages of 2′-O-methyl oligoribonucleotide probes for detecting RNA targets by Majlessi, Mehrdad, Nelson, Norman C., Becker, Michael M.

“…We have compared various kinetic and melting properties of oligoribonucleotide probes containing 2′-O-methylnucleotides or 2′-deoxynucleotides with regard to…”
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Portal and peripheral vein immunoreactive insulin concentrations before and after glucose infusion by Blackard, W G, Nelson, N C

“…Catheterization of the portal vein via the umbilical vein was performed under local anesthesia in twelve nondiabetic subjects prior to exploratory laporatomy…”
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Rhabdomyolysis: A Complication of Parathyroidectomy and Calcium Supplementation by Wooldridge, Thomas D, Bower, John D, Nelson, Norman C

“…HYPOPHOSPHATEMIA may result in a number of pathologic conditions. Fuller et al1 have called attention to the fact that rhabdomyolysis may be precipitated by…”
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Nucleophilic addition to the 9 position of 9-phenylcarboxylate-10-methylacridinium protects against hydrolysis of the ester by Hammond, P W, Wiese, W A, Waldrop, 3rd, A A, Nelson, N C, Arnold, Jr, L J

“…The chemiluminescent reaction of an acridinium ester (AE) requires addition of peroxide to the 9 position of the acridinium ring. The addition of a hydroxide…”
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Rapid Detection of Genetic Mutations Using the Chemiluminescent Hybridization Protection Assay (HPA): Overview and Comparison with Other Methods by Nelson, Norman C.

“…The detection of genetic mutations is of paramount importance for the study, diagnosis, and treatment of human genetic disease. Methods of detection generally…”
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Endemic goiter and endemic thyroid disorders by Gaitan, Eduardo, Nelson, Norman C., Poole, Galen V.

“…The primary role of iodine deficiency in goitrogenesis and the prevention and treatment of endemic goiter by iodine supplementation is firmly established…”
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Detection of All Single-Base Mismatches in Solution by Chemiluminescence by Nelson, Norman C., Hammond, Philip W., Matsuda, Eiji, Goud, Anil A., Becker, Michael M.

“…A rapid in-solution method for the detection of all 12 single-base mismatches is described. The technique is based on the hybridization protection assay (HPA)…”
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Invited commentary by Nelson, Norman C.

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Invited commentary by Nelson, Norman C.

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Vitreon, a short-term vitreoretinal tamponade by Blinder, K J, Peyman, G A, Desai, U R, Nelson, N C, Alturki, W, Paris, C L

“…This investigation of the liquid perfluorocarbon, perfluorophenanthrene (Vitreon), establishes its safety and efficacy as a short-term vitreoretinal tamponade…”
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Use of perfluoroperhydrophenanthrene in the management of suprachoroidal hemorrhages by Desai, U R, Peyman, G A, Chen, C J, Nelson, Jr, N C, Alturki, W A, Blinder, K J, Paris, C L

“…Suprachoroidal hemorrhage may cause the expulsion of intraocular contents. Generally, cases of nonexpulsive suprachoroidal hemorrhage have a better outcome…”
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Chemiluminescent DNA probes: a comparison of the acridinium ester and dioxetane detection systems and their use in clinical diagnostic assays by Nelson, N C, Kacian, D L

“…Nucleic acid hybridization has the potential to markedly improve the diagnosis of infectious and genetic diseases. Recently, chemiluminescent hybridization…”
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A technique for retinal pigment epithelium transplantation for age-related macular degeneration secondary to extensive subfoveal scarring by Peyman, G A, Blinder, K J, Paris, C L, Alturki, W, Nelson, Jr, N C, Desai, U

“…We describe the surgical excision of submacular scar in end-stage age-related macular degeneration and transplantation of autologous and homologous retinal…”
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Portal and peripheral vein immunoreactive glucagon concentrations after arginine or glucose infusions by Blackard, W G, Nelson, N C, Andrews, S S

“…Catheterization of the portal vein via the umbilical vein was performed under local anesthesia in eight nondiabetic subjects before exploratory laparotomy for…”
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Internal choroidectomy of posterior uveal melanomas under a retinal flap by Peyman, G A, Nelson, Jr, N C, Paris, C L, Blinder, K J, Alturki, W A, Desai, U R

“…Local excision of uveal melanoma is an intriguing therapeutic modality in selected cases. An internal choroidectomy under a retinal flap has been developed as…”
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Bimanual technique of subfoveal neovascular membrane removal in presumed ocular histoplasmosis by Peyman, G A, Lee, K J, Nelson, Jr, N C, Ma, P E

“…We describe a bimanual technique of subfoveal neovascular membrane removal in a patient with presumed ocular histoplasmosis syndrome. His postoperative vision…”
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Tissue plasminogen activating factor assisted removal of subretinal hemorrhage by Peyman, G A, Nelson, Jr, N C, Alturki, W, Blinder, K J, Paris, C L, Desai, U R, Harper, 3rd, C A

“…We used tissue plasminogen activator (tPA) to aid in the surgical evacuation of subretinal hemorrhages. Subretinal hemorrhage secondary to a ruptured retinal…”
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