Search Results - "Nelson, Mark"
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Assessing the vulnerability of marine life to climate change in the Pacific Islands region
Published in PloS one (08-07-2022)“…Our changing climate poses growing challenges for effective management of marine life, ocean ecosystems, and human communities. Which species are most…”
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2
Gathering Data for Archival, Field, Survey, and Experimental Accounting Research
Published in Journal of accounting research (01-05-2016)“…In the published proceedings of the first Journal of Accounting Research Conference, Vatter [1966] lamented that "Gathering direct and original facts is a…”
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3
Moving the Goalposts for Blood Pressure — Time to Act
Published in The New England journal of medicine (30-09-2021)“…We often lament the lack of confirmatory studies that can either reassure us all that the previous evidence for a trialed intervention is robust or indicate…”
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4
The history of the tetracyclines
Published in Annals of the New York Academy of Sciences (01-12-2011)“…The history of the tetracyclines involves the collective contributions of thousands of dedicated researchers, scientists, clinicians, and business executives…”
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5
If you look for primary aldosteronism, you find it
Published in Medical journal of Australia (02-05-2022)Get full text
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6
Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow
Published in Nature neuroscience (01-05-2017)“…Longden et al . demonstrate that brain capillaries function as a vast sensory web, monitoring neuronal activity by sensing K + and translating this into a K IR…”
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7
Biosphere 2’s Lessons about Living on Earth and in Space
Published in Space: science & technology (01-01-2021)“…Biosphere 2, the largest and most biodiverse closed ecological system facility yet created, has contributed vital lessons for living with our planetary…”
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8
PIP2: A critical regulator of vascular ion channels hiding in plain sight
Published in Proceedings of the National Academy of Sciences - PNAS (25-08-2020)“…The phosphoinositide, phosphatidylinositol 4,5-bisphosphate (PIP2), has long been established as a major contributor to intracellular signaling, primarily by…”
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9
A Vulnerability Assessment of Fish and Invertebrates to Climate Change on the Northeast U.S. Continental Shelf
Published in PloS one (03-02-2016)“…Climate change and decadal variability are impacting marine fish and invertebrate species worldwide and these impacts will continue for the foreseeable future…”
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Improving the management of cardiovascular disease risk in primary care
Published in Medical journal of Australia (01-05-2021)Get full text
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11
Contractile pericytes determine the direction of blood flow at capillary junctions
Published in Proceedings of the National Academy of Sciences - PNAS (27-10-2020)“…The essential function of the circulatory system is to continuously and efficiently supply the O2 and nutrients necessary to meet the metabolic demands of…”
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Vascular Inward Rectifier K+ Channels as External K+ Sensors in the Control of Cerebral Blood Flow
Published in Microcirculation (New York, N.Y. 1994) (01-04-2015)“…For decades it has been known that external K+ ions are rapid and potent vasodilators that increase CBF. Recent studies have implicated the local release of K+…”
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Climate vulnerability assessment for Pacific salmon and steelhead in the California Current Large Marine Ecosystem
Published in PloS one (24-07-2019)“…Major ecological realignments are already occurring in response to climate change. To be successful, conservation strategies now need to account for…”
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14
ATP- and voltage-dependent electro-metabolic signaling regulates blood flow in heart
Published in Proceedings of the National Academy of Sciences - PNAS (31-03-2020)“…Local control of blood flow in the heart is important yet poorly understood. Here we show that ATP-sensitive K⁺ channels (KATP), hugely abundant in cardiac…”
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15
Malleable Standards of Care Required by Jurors When Assessing Auditor Negligence
Published in The Accounting review (01-01-2017)“…We report the results of four experiments investigating the relationship between (1) the quality of an audit, (2) jurors' assessments of the standard of…”
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16
Absolute cardiovascular disease risk and the use of the Australian cardiovascular disease risk calculator
Published in Australian journal of general practice (01-08-2020)“…Primary prevention of cardiovascular disease (CVD) has been traditionally guided by individual risk factors such hypertension and hypercholesterolaemia. An…”
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Perturbations of the cerebrovascular matrisome: A convergent mechanism in small vessel disease of the brain?
Published in Journal of Cerebral Blood Flow & Metabolism (01-01-2016)“…The term matrisome refers to the ensemble of proteins constituting the extracellular matrix (ECM) (core matrisome) as well as the proteins associated with the…”
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Elementary Ca²⁺ Signals Through Endothelial TRPV4 Channels Regulate Vascular Function
Published in Science (American Association for the Advancement of Science) (04-05-2012)“…Major features of the transcellular signaling mechanism responsible for endothelium-dependent regulation of vascular smooth muscle tone are unresolved. We…”
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Ion channel networks in the control of cerebral blood flow
Published in Journal of Cerebral Blood Flow & Metabolism (01-03-2016)“…One hundred and twenty five years ago, Roy and Sherrington made the seminal observation that neuronal stimulation evokes an increase in cerebral blood flow.1…”
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20
PIP2 depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells
Published in eLife (07-08-2018)“…We recently reported that the inward-rectifier Kir2.1 channel in brain capillary endothelial cells (cECs) plays a major role in neurovascular coupling (NVC) by…”
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