Search Results - "Nelson, Joel"

Clinically Localized Prostate Cancer: AUA/ASTRO/SUO Guideline. Part I: Risk Stratification, Shared Decision Making, and Care Options by Sanda, Martin G., Cadeddu, Jeffrey A., Kirkby, Erin, Chen, Ronald C., Crispino, Tony, Fontanarosa, Joann, Freedland, Stephen J., Greene, Kirsten, Klotz, Laurence H., Makarov, Danil V., Nelson, Joel B., Rodrigues, George, Sandler, Howard M., Taplin, Mary Ellen, Treadwell, Jonathan R.

“…This guideline is structured to provide a clinical framework stratified by cancer severity to facilitate care decisions and guide the specifics of implementing…”
Get full text

Clinically Localized Prostate Cancer: AUA/ASTRO/SUO Guideline. Part II: Recommended Approaches and Details of Specific Care Options by Sanda, Martin G., Cadeddu, Jeffrey A., Kirkby, Erin, Chen, Ronald C., Crispino, Tony, Fontanarosa, Joann, Freedland, Stephen J., Greene, Kirsten, Klotz, Laurence H., Makarov, Danil V., Nelson, Joel B., Rodrigues, George, Sandler, Howard M., Taplin, Mary Ellen, Treadwell, Jonathan R.

“…This guideline is structured to provide a clinical framework stratified by cancer severity to facilitate care decisions and guide the specifics of implementing…”
Get full text

Protocol for the fast chromatin immunoprecipitation (ChIP) method by Bomsztyk, Karol, Nelson, Joel D, Denisenko, Oleg

“…Chromatin and transcriptional processes are among the most intensively studied fields of biology today. The introduction of chromatin immunoprecipitations…”
Get full text

The Ongoing Challenge of Urinary Incontinence after Radical Prostatectomy by Nelson, Joel B.

Get full text

A Contemporary Prostate Cancer Grading System: A Validated Alternative to the Gleason Score by Epstein, Jonathan I, Zelefsky, Michael J, Sjoberg, Daniel D, Nelson, Joel B, Egevad, Lars, Magi-Galluzzi, Cristina, Vickers, Andrew J, Parwani, Anil V, Reuter, Victor E, Fine, Samson W, Eastham, James A, Wiklund, Peter, Han, Misop, Reddy, Chandana A, Ciezki, Jay P, Nyberg, Tommy, Klein, Eric A

“…Abstract Background Despite revisions in 2005 and 2014, the Gleason prostate cancer (PCa) grading system still has major deficiencies. Combining of Gleason…”
Get full text

Relation between activity‐induced intracellular sodium transients and ATP dynamics in mouse hippocampal neurons by Gerkau, Niklas J., Lerchundi, Rodrigo, Nelson, Joel S. E., Lantermann, Marina, Meyer, Jan, Hirrlinger, Johannes, Rose, Christine R.

“…Key points Employing quantitative Na+‐imaging and Förster resonance energy transfer‐based imaging with ATeam1.03YEMK (ATeam), we studied the relation between…”
Get full text

Targeting genomic rearrangements in tumor cells through Cas9-mediated insertion of a suicide gene by Chen, Zhang-Hui, Yu, Yan P, Zuo, Ze-Hua, Nelson, Joel B, Michalopoulos, George K, Monga, Satdatshan, Liu, Silvia, Tseng, George, Luo, Jian-Hua

“…Insertion of the sequence encoding herpes simplex virus 1 thymidine kinase at the breakpoints of fusion genes in cancer cells causes cell death and regression…”
Get full text

Clinical Utility of the Risk Analysis Index as a Prospective Frailty Screening Tool within a Multi-practice, Multi-hospital Integrated Healthcare System by Varley, Patrick R., Borrebach, Jeffrey D., Arya, Shipra, Massarweh, Nader N., Bilderback, Andrew L., Wisniewski, Mary Kay, Nelson, Joel B., Johnson, Jonas T., Johanning, Jason M., Hall, Daniel E.

“…OBJECTIVE:The goal of this project was to first address barriers to implementation of the Risk Analysis Index (RAI) within a large, multi-hospital, integrated…”
Get full text

Phase III, Randomized, Placebo-Controlled Study of Docetaxel in Combination With Zibotentan in Patients With Metastatic Castration-Resistant Prostate Cancer by FIZAZI, Karim S, HIGANO, Celestia S, NELSON, Joel B, GLEAVE, Martin, MILLER, Kurt, MORRIS, Thomas, NATHAN, Faith E, MCINTOSH, Stuart, PEMBERTON, Kristine, MOUL, Judd W

“…PURPOSE As part of the ENTHUSE (Endothelin A Use) program, the efficacy and safety of zibotentan (ZD4054), an oral specific endothelin A receptor antagonist,…”
Get full text

Regulation and targeting of androgen receptor nuclear localization in castration-resistant prostate cancer by Lv, Shidong, Song, Qiong, Chen, Guang, Cheng, Erdong, Chen, Wei, Cole, Ryan, Wu, Zeyu, Pascal, Laura E, Wang, Ke, Wipf, Peter, Nelson, Joel B, Wei, Qiang, Huang, Wenhua, Wang, Zhou

“…Nuclear localization of the androgen receptor (AR) is necessary for its activation as a transcription factor. Defining the mechanisms regulating AR nuclear…”
Get full text

Association of Routine Preoperative Frailty Assessment With 1-Year Postoperative Mortality by Varley, Patrick R, Buchanan, Dan, Bilderback, Andrew, Wisniewski, Mary Kay, Johanning, Jason, Nelson, Joel B, Johnson, Jonas T, Minnier, Tamra, Hall, Daniel E

“…Patient frailty is a known risk factor for adverse outcomes following surgery, but data are limited regarding whether systemwide interventions related to…”
Get more information

Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets by Beltran, Himisha, Rickman, David S, Park, Kyung, Chae, Sung Suk, Sboner, Andrea, MacDonald, Theresa Y, Wang, Yuwei, Sheikh, Karen L, Terry, Stéphane, Tagawa, Scott T, Dhir, Rajiv, Nelson, Joel B, de la Taille, Alexandre, Allory, Yves, Gerstein, Mark B, Perner, Sven, Pienta, Kenneth J, Chinnaiyan, Arul M, Wang, Yuzhuo, Collins, Colin C, Gleave, Martin E, Demichelis, Francesca, Nanus, David M, Rubin, Mark A

“…Neuroendocrine prostate cancer (NEPC) is an aggressive subtype of prostate cancer that most commonly evolves from preexisting prostate adenocarcinoma (PCA)…”
Get more information

Rotavirus induces intercellular calcium waves through ADP signaling by Chang-Graham, Alexandra L, Perry, Jacob L, Engevik, Melinda A, Engevik, Kristen A, Scribano, Francesca J, Gebert, J Thomas, Danhof, Heather A, Nelson, Joel C, Kellen, Joseph S, Strtak, Alicia C, Sastri, Narayan P, Estes, Mary K, Britton, Robert A, Versalovic, James, Hyser, Joseph M

“…Rotavirus causes severe diarrheal disease in children by broadly dysregulating intestinal homeostasis. However, the underlying mechanism(s) of…”
Get full text

Environment and pathogens shape local and regional adaptations to climate change in the chocolate tree, Theobroma cacao L by Nelson, Joel T., Motamayor, Juan C., Cornejo, Omar E.

“…Predicting the potential fate of a species in the face of climate change requires knowing the distribution of molecular adaptations across the geographic range…”
Get full text

Disease and host characteristics as predictors of time to first bone metastasis and death in men with progressive castration‐resistant nonmetastatic prostate cancer by Smith, Matthew R., Cook, Richard, Lee, Ker‐Ai, Nelson, Joel B.

“…BACKGROUND: The natural history of castration‐resistant nonmetastatic prostate cancer is poorly defined. METHODS: The authors used data from 331 subjects in…”
Get full text

Concurrent AURKA and MYCN Gene Amplifications Are Harbingers of Lethal TreatmentRelated Neuroendocrine Prostate Cancer by Mosquera, Juan Miguel, Beltran, Himisha, Park, Kyung, MacDonald, Theresa Y, Robinson, Brian D, Tagawa, Scott T, Perner, Sven, Bismar, Tarek A, Erbersdobler, Andreas, Dhir, Rajiv, Nelson, Joel B, Nanus, David M, Rubin, Mark A

“…Abstract Neuroendocrine prostate cancer (NEPC), also referred to as anaplastic prostate cancer, is a lethal tumor that most commonly arises in late stages of…”
Get full text

SafeNET: Initial development and validation of a real-time tool for predicting mortality risk at the time of hospital transfer to a higher level of care by Altieri Dunn, Stefanie C, Bellon, Johanna E, Bilderback, Andrew, Borrebach, Jeffrey D, Hodges, Jacob C, Wisniewski, Mary Kay, Harinstein, Matthew E, Minnier, Tamra E, Nelson, Joel B, Hall, Daniel E

“…Processes for transferring patients to higher acuity facilities lack a standardized approach to prognostication, increasing the risk for low value care that…”
Get full text

Validation of the Risk Analysis Index for Evaluating Frailty in Ambulatory Patients by Shah, Rupen, Borrebach, Jeffrey D., Hodges, Jacob C., Varley, Patrick R., Wisniewski, Mary Kay, Shinall, Myrick C., Arya, Shipra, Johnson, Jonas, Nelson, Joel B., Youk, Ada, Massarweh, Nader N., Johanning, Jason M., Hall, Daniel E.

“…BACKGROUND Frailty is a marker of dependency, disability, hospitalization, and mortality in community‐dwelling older adults. However, existing tools for…”
Get full text

(+)-JJ-74-138 is a Novel Noncompetitive Androgen Receptor Antagonist by Cole, Ryan N, Chen, Wei, Pascal, Laura E, Nelson, Joel B, Wipf, Peter, Wang, Zhou

“…Identification of novel androgen receptor (AR) antagonists may lead to urgently needed new treatments for patients with prostate cancer resistant to current AR…”
Get full text

Hsp70 Binds to the Androgen Receptor N-terminal Domain and Modulates the Receptor Function in Prostate Cancer Cells by Dong, Jun, Wu, Zeyu, Wang, Dan, Pascal, Laura E, Nelson, Joel B, Wipf, Peter, Wang, Zhou

“…The androgen receptor (AR) is a key driver and therapeutic target in androgen-sensitive prostate cancer, castration-resistant prostate cancer (CRPC), and CRPC…”
Get full text