Search Results - "Nelson, J. Luke"

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  1. 1

    Molecular assays for the detection of microRNAs in prostate cancer by Siva, Amara C, Nelson, Luke J, Fleischer, Chad L, Majlessi, Mehrdad, Becker, Michael M, Vessella, Robert L, Reynolds, Mark A

    Published in Molecular cancer (06-03-2009)
    “…MicroRNAs (miRNAs) are small non-coding RNAs (about 21 to 24 nucleotides in length) that effectively reduce the translation of their target mRNAs. Several…”
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    Journal Article
  2. 2

    What Is the Effect of COVID-19-Related Social Distancing on Oral and Maxillofacial Trauma? by Ludwig, David C., Nelson, J. Luke, Burke, Andrea B., Lang, Melanie S., Dillon, Jasjit K.

    Published in Journal of oral and maxillofacial surgery (01-05-2021)
    “…The purpose of this study was to understand the impact of social distancing policies enacted during the COVID-19 pandemic on the epidemiology of oral and…”
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    Journal Article
  3. 3

    Ultrasonic Analytic-Signal Responses From Polymer-Matrix Composite Laminates by Smith, Robert A., Nelson, Luke J., Mienczakowski, Martin J., Wilcox, Paul D.

    “…Ultrasound has been used to inspect composite laminates since their invention but only recently has the response from the internal plies themselves been…”
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    Journal Article
  4. 4

    Src Kinase Is Biphosphorylated at Y416/Y527 and Activates the CUB-Domain Containing Protein 1/Protein Kinase C δ Pathway in a Subset of Triple-Negative Breast Cancers by Nelson, Luke J., Wright, Heather J., Dinh, Nguyen B., Nguyen, Kevin D., Razorenova, Olga V., Heinemann, F. Scott

    Published in The American journal of pathology (01-02-2020)
    “…Targeted therapeutics are needed for triple-negative breast cancer (TNBC). In this study, we investigated the activation of Src family of cytoplasmic tyrosine…”
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    Journal Article
  5. 5

    Odontogenic Infections: Disease Burden During COVID-19 at a Single Institution by Johnson, Robert E., Foy, Trayvon E., Ellingsen, Taylor A., Nelson, J. Luke, Dillon, Jasjit K.

    Published in Journal of oral and maxillofacial surgery (01-04-2021)
    “…The purpose of this study was to document the effect of coronavirus disease 2019 (COVID-19) on patients presenting to the University of Washington Oral and…”
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    Journal Article
  6. 6

    Synthetic lethality of cyclin-dependent kinase inhibitor Dinaciclib with VHL-deficiency allows for selective targeting of clear cell renal cell carcinoma by Nelson, Luke J, Castro, Kyleen E, Xu, Binzhi, Li, Junyi, Dinh, Nguyen B, Thompson, Jordan M, Woytash, Jordan, Kipp, Kevin R, Razorenova, Olga V

    Published in Cell cycle (Georgetown, Tex.) (19-05-2022)
    “…Clear cell renal cell carcinoma (CC-RCC) remains one of the most deadly forms of kidney cancer despite recent advancements in targeted therapeutics, including…”
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    Journal Article
  7. 7

    Targeting the Mevalonate Pathway Suppresses VHL-Deficient CC-RCC through an HIF-Dependent Mechanism by Thompson, Jordan M, Alvarez, Alejandro, Singha, Monika K, Pavesic, Matthew W, Nguyen, Quy H, Nelson, Luke J, Fruman, David A, Razorenova, Olga V

    Published in Molecular cancer therapeutics (01-08-2018)
    “…Clear cell renal cell carcinoma (CC-RCC) is a devastating disease with limited therapeutic options available for advanced stages. The objective of this study…”
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    Journal Article
  8. 8

    Abstract 6395: VHL deficiency sensitizes CC-RCC to inhibition of small GTPases by statins by Razorenova, Olga V., Thompson, Jordan M., Alvarez, Alejandro, Singha, Monika K., MW, Matthew W. Pavesic, Nguyen, Quy H., Nelson, Luke J., Fruman, David A.

    Published in Cancer research (Chicago, Ill.) (15-08-2020)
    “…Clear cell renal cell carcinoma (CC-RCC) type of kidney cancer has limited therapeutic options available for advanced stages. The objective of this study was…”
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    Journal Article
  9. 9

    Rho-associated kinase 1 inhibition is synthetically lethal with von Hippel-Lindau deficiency in clear cell renal cell carcinoma by Thompson, J M, Nguyen, Q H, Singh, M, Pavesic, M W, Nesterenko, I, Nelson, L J, Liao, A C, Razorenova, O V

    Published in Oncogene (23-02-2017)
    “…Clear cell renal cell carcinoma (CC-RCC) is the most lethal of all genitourinary cancers. The functional loss of the von Hippel-Lindau ( VHL ) gene occurs in…”
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    Journal Article
  10. 10

    Abstract PR15: Rho-associated kinase 1 inhibition is synthetically lethal with von Hippel-Lindau deficiency in clear cell renal cell carcinoma by Thompson, Jordan M., Nguyen, Quy H., Singh, Manpreet, Pavesic, Matthew W., Nesterenko, Irina, Nelson, Luke J., Liao, Alicia, Razorenova, Olga V.

    Published in Molecular cancer therapeutics (01-10-2017)
    “…Clear cell renal cell carcinoma (CC-RCC) is the most lethal of all genitourinary cancers. The functional loss of the von Hippel-Lindau (VHL) gene occurs in 90%…”
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    Journal Article
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  12. 12

    Characterisation and modelling of active fibre composites by Nelson, Luke J

    Published 01-01-2005
    “…The objective of this study is to examine the major components of a newly developed active composite configuration, and to use the understanding gained to…”
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    Dissertation