Search Results - "Nelson, David"
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Cytochrome P450 diversity in the tree of life
Published in Biochimica et biophysica acta. Proteins and proteomics (01-01-2018)“…Sequencing in all areas of the tree of life has produced >300,000 cytochrome P450 (CYP) sequences that have been mined and collected. Nomenclature has been…”
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The mechanism of host-induced germination in root parasitic plants
Published in Plant physiology (Bethesda) (23-04-2021)“…Chemical signals known as strigolactones (SLs) were discovered more than 50 years ago as host-derived germination stimulants of parasitic plants in the…”
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The cytochrome p450 homepage
Published in Human genomics (01-10-2009)“…The Cytochrome P450 Homepage is a universal resource for nomenclature and sequence information on cytochrome P450 ( CYP ) genes. The site has been in…”
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Strigolactone Signaling and Evolution
Published in Annual review of plant biology (28-04-2017)“…Strigolactones are a structurally diverse class of plant hormones that control many aspects of shoot and root growth. Strigolactones are also exuded by plants…”
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Evolution of Plant Hormone Response Pathways
Published in Annual review of plant biology (29-04-2020)“…This review focuses on the evolution of plant hormone signaling pathways. Like the chemical nature of the hormones themselves, the signaling pathways are…”
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Optimizing Catalyst and Reaction Conditions in Gold(I) Catalysis–Ligand Development
Published in Chemical reviews (28-07-2021)“…This review considers phosphine and N-heterocyclic carbene complexes of gold(I) that are used as (pre)catalysts for a range of reactions in organic…”
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2022 Victor A. McKusick Leadership Award
Published in American journal of human genetics (02-03-2023)“…This article is based on the address given by the author at the 2022 meeting of The American Society of Human Genetics (ASHG) in Los Angeles, CA. The video of…”
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Progress in tracing the evolutionary paths of cytochrome P450
Published in Biochimica et biophysica acta (2011)“…The state of cytochrome P450 sequence accumulation in different phyla is summarized. 12,456 P450s are currently named, with about 6000 more that are known, but…”
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Breast cancer-specific mortality in early breast cancer as defined by high-risk clinical and pathologic characteristics
Published in PloS one (25-02-2022)“…To investigate breast cancer-specific mortality by early breast cancer (EBC; Stages I-IIIC) subtype; incidence of high-risk indicators for recurrence (defined…”
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The Unstable Repeats—Three Evolving Faces of Neurological Disease
Published in Neuron (Cambridge, Mass.) (06-03-2013)“…Disorders characterized by expansion of an unstable nucleotide repeat account for a number of inherited neurological diseases. Here, we review examples of…”
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Advances in microalgal research and engineering development
Published in Current opinion in biotechnology (01-10-2019)“…[Display omitted] Microalgae have been investigated for the photosynthetic production of natural products with industrial and biomedical applications. Their…”
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Accessible Syntheses of Late Transition Metal (Pre)Catalysts Bearing N-Heterocyclic Carbene Ligands
Published in European journal of inorganic chemistry (01-04-2015)“…This microreview details and discusses some selected examples of the accessible syntheses of useful complexes bearing N‐heterocyclic carbenes (NHCs). The term…”
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A world of cytochrome P450s
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (19-02-2013)“…The world we live in is a biosphere influenced by all organisms who inhabit it. It is also an ecology of genes, with some having rather startling effects. The…”
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Plant cytochrome P450 plasticity and evolution
Published in Molecular plant (02-08-2021)“…The superfamily of cytochrome P450 (CYP) enzymes plays key roles in plant evolution and metabolic diversification. This review provides a status on the CYP…”
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Stephen T. Warren 1953–2021
Published in Nature genetics (01-08-2021)“…Stephen T. Warren was a key contributor to the 1991 discovery of an unstable trinucleotide repeat that expands in families and causes loss of function in…”
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Status of Direct-Acting Antiviral Therapy for Hepatitis C Virus Infection and Remaining Challenges
Published in Gastroenterology (New York, N.Y. 1943) (01-01-2019)“…Chronic infection with hepatitis C virus is a major cause of liver disease and hepatocellular carcinoma worldwide. After the discovery of hepatitis C virus 3…”
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Elastic Instability of a Crystal Growing on a Curved Surface
Published in Science (American Association for the Advancement of Science) (07-02-2014)“…Although the effects of kinetics on crystal growth are well understood, the role of substrate curvature is not yet established. We studied rigid,…”
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Co‐packaged datacenter optics: Opportunities and challenges
Published in IET optoelectronics (01-04-2021)“…High‐capacity, high‐density, power‐, and cost‐efficient optical links are undoubtedly of critical importance for datacenter infrastructure. However, the optics…”
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Oral Direct-Acting Agent Therapy for Hepatitis C Virus Infection: A Systematic Review
Published in Annals of internal medicine (02-05-2017)“…Rapid improvements in hepatitis C virus (HCV) therapy have led to the approval of multiple oral direct-acting antiviral (DAA) regimens by the U.S. Food and…”
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