Search Results - "Nelson, Amy J."

Neural Representation of Subjective Value Under Risk and Ambiguity by Levy, Ifat, Snell, Jason, Nelson, Amy J, Rustichini, Aldo, Glimcher, Paul W

“…1 Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut; 2 Center for Neural Science, 3 Departments of Psychology and 4…”
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Post-endotoxin exposure-induced lung inflammation and resolution consequences beneficially impacted by lung-delivered IL-10 therapy by Poole, Jill A., Gaurav, Rohit, Schwab, Aaron, Nelson, Amy J., Gleason, Angela, Romberger, Debra J., Wyatt, Todd A.

“…Although lung diseases typically result from long-term exposures, even a robust, one-time exposure can result in long-lasting consequences. Endotoxin is a…”
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High-throughput analysis of lung immune cells in a combined murine model of agriculture dust-triggered airway inflammation with rheumatoid arthritis by Gaurav, Rohit, Mikuls, Ted R, Thiele, Geoffrey M, Nelson, Amy J, Niu, Meng, Guda, Chittibabu, Eudy, James D, Barry, Austin E, Wyatt, Todd A, Romberger, Debra J, Duryee, Michael J, England, Bryant R, Poole, Jill A

“…Rheumatoid arthritis (RA)-associated lung disease is a leading cause of mortality in RA, yet the mechanisms linking lung disease and RA remain unknown. Using…”
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Combined Collagen‐Induced Arthritis and Organic Dust‐Induced Airway Inflammation to Model Inflammatory Lung Disease in Rheumatoid Arthritis by Poole, Jill A, Thiele, Geoffrey M, Janike, Katherine, Nelson, Amy J, Duryee, Michael J, Rentfro, Kathryn, England, Bryant R, Romberger, Debra J, Carrington, Joseph M, Wang, Dong, Swanson, Benjamin J, Klassen, Lynell W, Mikuls, Ted R

“…ABSTRACT Rheumatoid arthritis (RA) is characterized by extra‐articular involvement including lung disease, yet the mechanisms linking the two conditions are…”
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Targeting transitioning lung monocytes/macrophages as treatment strategies in lung disease related to environmental exposures by Schwab, Aaron D, Wyatt, Todd A, Moravec, Grace, Thiele, Geoffrey M, Nelson, Amy J, Gleason, Angela, Schanze, Oliver, Duryee, Michael J, Romberger, Debra J, Mikuls, Ted R, Poole, Jill A

“…Environmental/occupational exposures cause significant lung diseases. Agricultural organic dust extracts (ODE) and bacterial component lipopolysaccharide (LPS)…”
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Ovalbumin-sensitized mice have altered airway inflammation to agriculture organic dust by Warren, Kristi J, Dickinson, John D, Nelson, Amy J, Wyatt, Todd A, Romberger, Debra J, Poole, Jill A

“…Agriculture exposures are associated with reducing the risk of allergy and asthma in early life; yet, repeated exposures later in life are associated with…”
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Lung-delivered IL-10 therapy elicits beneficial effects via immune modulation in organic dust exposure-induced lung inflammation by Schwab, Aaron D, Wyatt, Todd A, Nelson, Amy J, Gleason, Angela, Gaurav, Rohit, Romberger, Debra J, Poole, Jill A

“…Efficacious therapeutic options capable of resolving inflammatory lung disease associated with environmental and occupational exposures are lacking. This study…”
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Relationships of serum CC16 levels with smoking status and lung function in COPD by Gribben, Kelli C, Poole, Jill A, Nelson, Amy J, Farazi, Paraskevi A, Wichman, Christopher S, Heires, Art J, Romberger, Debra J, LeVan, Tricia D

“…The club cell secretory protein (CC16) has anti-inflammatory and antioxidant effects, and low CC16 serum levels have been associated with both risk and…”
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Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures by Schwab, Aaron D, Nelson, Amy J, Gleason, Angela M, Schanze, Oliver W, Wyatt, Todd A, Shinde, Dhananjay D, Xiao, Peng, Thomas, Vinai C, Guda, Chittibabu, Bailey, Kristina L, Kielian, Tammy, Thiele, Geoffrey M, Poole, Jill A

“…Environmental lipopolysaccharide (LPS) and microbial component-enriched organic dusts cause significant lung disease. These environmental exposures induce the…”
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Increased susceptibility to organic dust exposure-induced inflammatory lung disease with enhanced rheumatoid arthritis-associated autoantigen expression in HLA-DR4 transgenic mice by Poole, Jill A, Mikuls, Ted R, Thiele, Geoffrey M, Gaurav, Rohit, Nelson, Amy J, Duryee, Michael J, Mitra, Ananya, Hunter, Carlos, Wyatt, Todd A, England, Bryant R, Ascherman, Dana P

“…Immunogenetic as well as environmental and occupational exposures have been linked to the development of rheumatoid arthritis (RA), RA-associated lung disease,…”
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Sex differences in activation of lung-related type 2 innate lymphoid cells in experimental asthma by Warren, Kristi J., PhD, Sweeter, Jenea M., MS, Pavlik, Jacqueline A., BS, Nelson, Amy J., BS, Devasure, Jane M., BS, Dickinson, John D., MD, PhD, Sisson, Joseph H., MD, Wyatt, Todd A., PhD, Poole, Jill A., MD

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MyD88 regulates a prolonged adaptation response to environmental dust exposure-induced lung disease by Johnson, Amber N, Harkema, Jack R, Nelson, Amy J, Dickinson, John D, Kalil, Julianna, Duryee, Michael J, Thiele, Geoffrey M, Kumar, Balawant, Singh, Amar B, Gaurav, Rohit, Glover, Sarah C, Tang, Ying, Romberger, Debra J, Kielian, Tammy, Poole, Jill A

“…Environmental organic dust exposures enriched in Toll-like receptor (TLR) agonists can reduce allergic asthma development but are associated with occupational…”
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Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease by Ikari, Jun, Nelson, Amy J, Obaid, Jannah, Giron-Martinez, Alvaro, Ikari, Kumiko, Makino, Fumihiko, Iwasawa, Shunichiro, Gunji, Yoko, Farid, Maha, Wang, Xingqi, Basma, Hesham, Demeo, Dawn, Feghali-Bostwick, Carol, Holz, Olaf, Rabe, Klaus, Liu, Xiangde, Rennard, Stephen I

“…Alterations in microRNA (miRNA) expression may contribute to COPD pathogenesis. In COPD, lung fibroblast repair functions are altered in multiple ways,…”
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A role for B cells in organic dust induced lung inflammation by Poole, Jill A, Mikuls, Ted R, Duryee, Michael J, Warren, Kristi J, Wyatt, Todd A, Nelson, Amy J, Romberger, Debra J, West, William W, Thiele, Geoffrey M

“…Agriculture organic dust exposures induce lung disease with lymphoid aggregates comprised of both T and B cells. The precise role of B cells in mediating lung…”
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Sex differences impact the lung-bone inflammatory response to repetitive inhalant lipopolysaccharide exposures in mice by Nelson, Amy J., Roy, Shyamal K., Warren, Kristi, Janike, Katherine, Thiele, Geoffrey M., Mikuls, Ted R., Romberger, Debra J., Wang, Dong, Swanson, Benjamin, Poole, Jill A.

“…Skeletal health consequences associated with inflammatory diseases of the airways significantly contribute to morbidity. Sex differences have been described…”
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Prostaglandin E2 switches from a stimulator to an inhibitor of cell migration after epithelial-to-mesenchymal transition by Li, Ying-Ji, Kanaji, Nobuhiro, Wang, Xing-Qi, Sato, Tadashi, Nakanishi, Masanori, Kim, Miok, Michalski, Joel, Nelson, Amy J., Farid, Maha, Basma, Hesham, Patil, Amol, Toews, Myron L., Liu, Xiangde, Rennard, Stephen I.

“…•PGE2 inhibits fibroblast migration, but stimulates epithelial cell chemotaxis.•Epithelial cells undergo mesenchymal transition (EMT) in response to TGF-β1 and…”
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Post-injury and resolution response to repetitive inhalation exposure to agricultural organic dust in mice by Warren, Kristi J, Wyatt, Todd A, Romberger, Debra J, Ailts, Isaak, West, William W, Nelson, Amy J, Nordgren, Tara M, Staab, Elizabeth, Heires, Art J, Poole, Jill A

“…Inhalation of organic dusts in agricultural environments causes airway inflammatory diseases. Despite advances in understanding the airway response to…”
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Innovation acceleration, digitization, and the crisis of nonproliferation systems by Nelson, Amy J.

“…Nonproliferation systems comprise agreements designed to work in concert to manage specific security risks. New technologies, however, are exacerbating these…”
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Amphiregulin modulates murine lung recovery and fibroblast function following exposure to agriculture organic dust by Poole, Jill A, Nordgren, Tara M, Heires, Art J, Nelson, Amy J, Katafiasz, Dawn, Bailey, Kristina L, Romberger, Debra J

“…Exposure to agricultural bioaerosols can lead to chronic inflammatory lung diseases. Amphiregulin (AREG) can promote the lung repair process but can also lead…”
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Unique transcriptomic profile of peripheral blood monocytes in rheumatoid arthritis-associated interstitial lung disease by Poole, Jill A, Schwab, Aaron, Thiele, Geoffrey M, England, Bryant R, Nelson, Amy J, Gleason, Angela, Duryee, Michael J, Bailey, Kristina L, Romberger, Debra J, Hershberger, Daniel, Van De Graaff, Joel, May, Sara M, Walenz, Rhonda, Kramer, Bridget, Mikuls, Ted R

“…Though interstitial lung disease (ILD) contributes to excess morbidity and mortality in rheumatoid arthritis (RA), RA-ILD pathogenesis remains incompletely…”
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