Search Results - "Nelsen, Linda M."

Efficacy of mepolizumab add-on therapy on health-related quality of life and markers of asthma control in severe eosinophilic asthma (MUSCA): a randomised, double-blind, placebo-controlled, parallel-group, multicentre, phase 3b trial by Chupp, Geoffrey L, Prof, Bradford, Eric S, MD, Albers, Frank C, MD, Bratton, Daniel J, PhD, Wang-Jairaj, Jie, MD, Nelsen, Linda M, MHS, Trevor, Jennifer L, MD, Magnan, Antoine, Prof, ten Brinke, Anneke, MD

“…Summary Background Mepolizumab, an anti-interleukin-5 monoclonal antibody approved as add-on therapy to standard of care for patients with severe eosinophilic…”
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Reliability, validity and responsiveness of E-RS:COPD in patients with spirometric asthma-COPD overlap by Nelsen, Linda M, Lee, Laurie A, Wu, Wei, Lin, Xiwu, Murray, Lindsey, Pascoe, Steven J, Leidy, Nancy K

“…The Evaluating Respiratory Symptoms in Chronic Obstructive Pulmonary Disease (E-RS:COPD) is a patient-reported diary that assesses respiratory symptoms in…”
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Congenital malformations among infants born to women receiving montelukast, inhaled corticosteroids, and other asthma medications by Nelsen, Linda M., MHS, Shields, Kristine E., MSN, MPH, Cunningham, Michael L., MD, PhD, Stoler, Joan M., MD, Bamshad, Michael J., MD, Eng, P. Mona, ScD, Smugar, Steven S., MD, Gould, A. Lawrence, PhD, Philip, George, MD

“…Montelukast cohort: at least 1 prescription for montelukast (in addition to any other asthma drugs); ICS cohort: at least 1 prescription for an ICS (in…”
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Mepolizumab Significantly Improves Health Status and Asthma Control in Severe Eosinophilic Asthma: The Musca Study - a Phase IIIb Randomized, Placebo-Controlled Trial by Chupp, Geoffrey L., Prof, Bradford, Eric S., Dr, Albers, Frank C., Dr, Bratton, Daniel J., Dr, Wang-Jairaj, Jie, Dr, Nelsen, Linda M., Ms, Trevor, Jennifer L., Prof, Magnan, Antoine, Prof, ten Brinke, Anneke, Dr

“…Methods MUSCA was a Phase IIIb, placebo-controlled, randomized, double-blind, parallel-group, multicenter study (200862/NCT02281318) in patients with SEA and a…”
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Mepolizumab Improves Lung Function and Exacerbation Rates in Severe Eosinophilic Asthma: The Musca Study - a Phase IIIb Randomized, Placebo-Controlled Tria by Trevor, Jennifer L., Prof, Bradford, Eric S., Dr, Albers, Frank C., Dr, Bratton, Daniel J., Dr, Wang-Jairaj, Jie, Dr, Nelsen, Linda M., Ms, Chupp, Geoffrey L., Prof, Magnan, Antoine, Prof, ten Brinke, Anneke, Dr

“…Efficacy endpoints included pre-bronchodilator forced expiratory volume in 1s (FEV1), forced expiratory flow (FEF25-75), and forced vital capacity (FVC) at…”
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Intermittent or daily montelukast versus placebo for episodic asthma in children by Valovirta, Erkka, MD, PhD, Boza, Maria L., MD, Robertson, Colin F., MBBS, MSc, MD, Verbruggen, Nadia, MSc, Smugar, Steven S., MD, Nelsen, Linda M., MHS, Knorr, Barbara A., MD, Reiss, Theodore F., MD, Philip, George, MD, Gurner, Deborah M., MD, PhD

“…Background No standard, optimal treatment exists for severe intermittent (ie, episodic) asthma in children. However, evidence suggests that both daily and…”
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Key Concepts of Migraine Postdrome: A Qualitative Study to Develop a Post-Migraine Questionnaire by Ng-Mak, Daisy S., Fitzgerald, Kristina A., Norquist, Josephine M., Banderas, Benjamin F., Nelsen, Linda M., Evans, Christopher J., Healy, Cynthia G., Ho, Tony W., Bigal, Marcelo

“…(Headache 2011;51:105‐117) Objective.— To understand migraine postdrome by directly interviewing migraine patients with postdrome symptoms. To document these…”
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Severe eosinophilic asthma with nasal polyposis: A phenotype for improved sinonasal and asthma outcomes with mepolizumab therapy by Howarth, Peter, Chupp, Geoffrey, Nelsen, Linda M., Bradford, Eric S., Bratton, Daniel J., Smith, Steven G., Albers, Frank C., Brusselle, Guy, Bachert, Claus

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Clinical characteristics and burden of illness among adolescent and adult patients with severe asthma by asthma control: the IDEAL study by Müllerová, Hana, Cockle, Sarah M., Gunsoy, Necdet B., Nelsen, Linda M., Albers, Frank C.

“…Severe asthma (SA) can be uncontrolled despite guideline-directed treatment. We described SA characteristics and identified factors associated with…”
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A structured review evaluating content validity of the Asthma Control Test, and its consistency with U.S. guidelines and patient expectations for asthma control by Nelsen, Linda M., Kosinski, Mark, Rizio, Avery A., Jacques, Loretta, Schatz, Michael, Stanford, Richard H., Svedsater, Henrik

“…To assess whether the content of the Asthma Control Test (ACT) served as a valid measure of asthma control (i.e., content validity) by mapping ACT items to the…”
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Biologic treatment eligibility for real-world patients with severe asthma: The IDEAL study by Albers, Frank C., Müllerová, Hana, Gunsoy, Necdet B., Shin, Ji-Yeon, Nelsen, Linda M., Bradford, Eric S., Cockle, Sarah M., Suruki, Robert Y.

“…Objectives: Severe asthma comprises several distinct phenotypes. Consequently, patients with severe asthma can be eligible for more than one biologic treatment…”
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Adherence to Prescribed Treatment for Asthma: Evidence from Pharmacy Benefits Data by Jones, Craig, Santanello, Nancy C., Boccuzzi, Steve J., Wogen, Jenifer, Strub, Peg, Nelsen, Linda M.

“…Background. Failure to use asthma controller medications as prescribed is associated with more asthma-related adverse events. Medication utilization may vary…”
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Niraparib and dostarlimab for the treatment of recurrent platinum-resistant ovarian cancer: results of a Phase II study (MOONSTONE/GOG-3032) by Randall, Leslie M., O'Malley, David M., Monk, Bradley J., Coleman, Robert L., Gaillard, Stephanie, Adams, Sarah, Duska, Linda R., Dalton, Heather, Holloway, Robert W., Huang, Marilyn, Chon, Hye Sook, Cloven, Noelle G., ElNaggar, Adam C., O'Cearbhaill, Roisin E., Waggoner, Steven, Tarkar, Aarti, Striha, Alina, Nelsen, Linda M., Baines, Amanda, Samnotra, Vivek, Konstantinopoulos, Panagiotis A.

“…This study assessed the efficacy, safety, and health-related quality of life (HRQoL) of the treatment regimen of dostarlimab, a programmed death-1 inhibitor,…”
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Understanding the Patient Experience of Severe, Recurrent, Bilateral Nasal Polyps: A Qualitative Interview Study in the United States and Germany by Hall, Rebecca, Trennery, Claire, Chan, Robert, Gater, Adam, Bradley, Helena, Sikirica, Mirko V., von Maltzahn, Robyn, Sousa, Ana R., Nelsen, Linda M.

“…To qualitatively explore patient experiences of severe, recurrent, bilateral nasal polyps (NP). A targeted literature review of published qualitative studies…”
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A Patient-reported Outcome Measure for Effect of Glucocorticoid Therapy in Adults with Inflammatory Diseases Is Needed: Report from the OMERACT 2016 Special Interest Group by Black, Rachel J, Robson, Joanna C, Goodman, Susan M, Hoon, Elizabeth, Lai, Lana Y H, Simon, Lee S, Harrison, Eileen, Neill, Lorna, Richards, Pam, Nelsen, Linda M, Nebesky, J Michael, Mackie, Sarah L, Hill, Catherine L

“…The need for a standardized instrument to measure the effect of glucocorticoid (GC) therapy has been well documented in the literature. The aim of the first GC…”
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Impact of exacerbations on St George's Respiratory Questionnaire score in patients with severe asthma: post hoc analyses of two clinical trials and an observational study by Nelsen, Linda M., Cockle, Sarah M., Gunsoy, Necdet B., Jones, Paul, Albers, Frank C., Bradford, Eric S., Mullerova, Hana

“…Objective: To assess the effect of asthma exacerbations and mepolizumab treatment on health status of patients with severe asthma using the St George's…”
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Qualitative evaluation of the St George's Respiratory Questionnaire in patients with severe asthma by Nelsen, Linda M, Kimel, Miriam, Murray, Lindsey T, Ortega, Hector, Cockle, Sarah M, Yancey, Steven W, Brusselle, Guy, Albers, Frank C, Jones, Paul W

“…Abstract Purpose Content validity is the extent to which a patient-reported outcome measure evaluates the concepts most relevant to a patient's condition and…”
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Experience of Symptoms and Disease Impact in Patients with Adenomyosis by Nelsen, Linda M., Lenderking, William R., Pokrzywinski, Robin, Balantac, Zaneta, Black, Libby, Pokras, Shibani, Enslin, Mary Beth, Cooper, Melisa, Lukes, Andrea S.

“…Background Adenomyosis is a poorly understood, benign disease of the uterus. Objective In this study, patient interviews were conducted to characterize the…”
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Symptom assessment in hypereosinophilic syndrome: Toward development of a patient-reported outcomes tool by Kovacs, Nicholas, Benjamin, Katy, Holland-Thomas, Nicole, Moshkovich, Olga, Nelsen, Linda M., Ortega, Hector, Schwartz, Ethan J., Steinfeld, Jonathan, Kirby, Suyong Yun, Klion, Amy, Khoury, Paneez

“…A patient-reported outcomes (PROs) instrument measuring symptoms of HES would provide valuable information for use in clinical practice as well as inform…”
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Evaluation of the psychometric properties of the St George's Respiratory Questionnaire in patients with severe asthma by Nelsen, Linda M, Vernon, Margaret, Ortega, Hector, Cockle, Sarah M, Yancey, Steven W, Brusselle, Guy, Albers, Frank C, Jones, Paul W

“…Abstract Purpose Limited data exist on the quantitative validity of the St George's Respiratory Questionnaire (SGRQ) in asthma populations. This study…”
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