Search Results - "Nelsen, Andrew C."
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Development of the Pulmonary Hypertension Functional Classification Self-Report: a patient version adapted from the World Health Organization Functional Classification measure
Published in Health and quality of life outcomes (24-08-2021)“…Abstract Background Pulmonary arterial hypertension (PAH) is characterized by progressive limitations on physical activity, right heart failure, and premature…”
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Bronchodilation induced by PGE2 is impaired in Group III pulmonary hypertension
Published in British journal of pharmacology (01-01-2020)“…Background and Purpose In patients with pulmonary hypertension (PH) associated with lung disease and/or hypoxia (Group III), decreased pulmonary vascular tone…”
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3
Medullary pain facilitating neurons mediate allodynia in headache-related pain
Published in Annals of neurology (01-02-2009)“…Objective To develop and validate a model of cutaneous allodynia triggered by dural inflammation for pain associated with headaches. To explore neural…”
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Medication Adherence and Healthcare Costs Among Patients with Pulmonary Arterial Hypertension Treated with Oral Prostacyclins: A Retrospective Cohort Study
Published in Drugs -- real world outcomes (01-09-2020)“…Background Given the improved convenience of oral prostacyclins, there is a shift toward their use in treating pulmonary arterial hypertension (PAH)…”
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Impact of inhaled treprostinil on risk stratification with noninvasive parameters: a post hoc analysis of the TRIUMPH and BEAT studies
Published in Pulmonary circulation (01-10-2020)“…The 2015 European Society of Cardiology/European Respiratory Society treatment guidelines recommend frequent risk assessment in pulmonary arterial hypertension…”
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Real‐world dosing characteristics and utilization of parenteral treprostinil in the outpatient setting
Published in Pulmonary circulation (01-01-2022)“…Real‐world dosing and titration of parenteral (subcutaneous, SC; intravenous, IV) prostacyclin, a mainstay of pulmonary arterial hypertension (PAH) treatment,…”
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Pulmonary hypertension due to interstitial lung disease or chronic obstructive pulmonary disease: a patient experience study of symptoms and their impact on quality of life
Published in Pulmonary circulation (01-04-2021)“…Pulmonary hypertension resulting from chronic lung disease such as chronic obstructive pulmonary disease and interstitial lung disease is categorized by the…”
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Survival and drug persistence in patients receiving inhaled treprostinil at doses greater than 54 µg (nine breaths) four times daily
Published in Pulmonary circulation (01-10-2021)“…Treprostinil is a prostacyclin approved for the treatment of pulmonary arterial hypertension. Commercial data sets indicate that approximately 20–25% of…”
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Implantable system for treprostinil: a real-world patient experience study
Published in Pulmonary circulation (01-04-2020)“…Parenteral prostanoids are effective for improving outcomes in patients with pulmonary arterial hypertension. However, subcutaneous or intravenous delivery via…”
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Correction to: Medication Adherence and Healthcare Costs Among Patients with Pulmonary Arterial Hypertension Treated with Oral Prostacyclins: A Retrospective Cohort Study
Published in Drugs -- real world outcomes (01-09-2020)“…Changes within text are indicated in bold…”
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11
Dosing characteristics of oral treprostinil in real-world clinical practice
Published in Pulmonary circulation (01-04-2018)“…Pharmacokinetic studies with oral treprostinil demonstrate that three times daily (TID) dosing reduces peak-to-trough plasma trepostinil fluctuations compared…”
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High-resolution HLA genotyping and severe cutaneous adverse reactions in lamotrigine-treated patients
Published in Pharmacogenetics and genomics (01-09-2009)Get full text
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13
Contemporary risk scores predict clinical worsening in pulmonary arterial hypertension - An analysis of FREEDOM-EV
Published in The Journal of heart and lung transplantation (01-11-2022)“…[Display omitted] Risk scores integrate clinical variables emphasizing symptoms, exercise capacity, and measures of cardiac strain to predict clinical outcome…”
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14
The Influence of CYP3A5 Genotype on Dexamethasone Induction of CYP3A Activity in African Americans
Published in Drug metabolism and disposition (01-08-2008)“…The CYP3A5 * 1 allele has been associated with differences in the metabolism of some CYP3A substrates. CYP3A5 polymorphism may also influence susceptibility…”
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15
Identifying Patients with Pulmonary Arterial Hypertension Using Administrative Claims Algorithms
Published in Annals of the American Thoracic Society (01-07-2019)“…Retrospective administrative claims database studies provide real-world evidence about treatment patterns, healthcare resource use, and costs for patients and…”
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16
The impact of delayed treatment on 6-minute walk distance test in patients with pulmonary arterial hypertension: A meta-analysis
Published in International journal of cardiology (01-03-2018)“…The impact of treatment delay in stable patients with pulmonary arterial hypertension (PAH) remains unaddressed. This meta-analysis included six datasets of…”
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17
Bronchodilation induced by PGE 2 is impaired in Group III pulmonary hypertension
Published in British journal of pharmacology (01-01-2020)“…In patients with pulmonary hypertension (PH) associated with lung disease and/or hypoxia (Group III), decreased pulmonary vascular tone and tissue hypoxia is…”
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18
High-resolution HLA genotyping and severe cutaneous adverse reactions in lamotrigine-treated patients
Published in Pharmacogenetics and genomics (01-09-2009)“…BACKGROUNDSevere cutaneous adverse reactions (SCARs) are associated with over 200 medicines including lamotrigine, an antiepileptic drug. Previous studies have…”
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Treatment satisfaction is associated with improved quality of life in patients treated with inhaled treprostinil for pulmonary arterial hypertension
Published in Health and quality of life outcomes (06-03-2013)“…Patient treatment satisfaction is likely to be a highly relevant outcome measure in pulmonary arterial hypertension (PAH), a condition for which the benefits…”
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Rapid transition from inhaled iloprost to inhaled treprostinil in patients with pulmonary arterial hypertension
Published in Cardiovascular therapeutics (01-02-2013)“…Inhaled treprostinil is a prostacyclin analog approved for the treatment of pulmonary arterial hypertension (PAH) that may provide a more convenient treatment…”
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