Search Results - "Nelissen, Jelly"

Dual NEP/ECE inhibition improves endothelial function in mesenteric resistance arteries of 32-week-old SHR by Lemkens, Pieter, Spijkers, Leon Ja, Meens, Merlijn J, Nelissen, Jelly, Janssen, Ben, Peters, Stephan Lm, Schiffers, Paul Mh, De Mey, Jo Gr

“…Endothelin 1 (ET-1), a potent vasoconstrictor, pro-mitogenic and pro-inflammatory peptide, may promote development of endothelial dysfunction and arterial…”
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Identification of free nitric oxide radicals in rat bone marrow: implications for progenitor cell mobilization in hypertension by Aleksinskaya, Marina A, van Faassen, Ernst E H, Nelissen, Jelly, Janssen, Ben J A, De Mey, Jo G R, Hanemaaijer, Roeland, Rabelink, Ton, van Zonneveld, Anton Jan

“…Nitric oxide (NO) has been implicated in matrix metallopeptidase 9 (MMP9)-dependent mobilization of hematopoietic stem and progenitor cells from bone marrow…”
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Calcitonin Gene-Related Peptide Terminates Long-Lasting Vasopressor Responses to Endothelin 1 In Vivo by Meens, Merlijn J.P.M.T, Mattheij, Nadine J.A, Nelissen, Jelly, Lemkens, Pieter, Compeer, Matthijs G, Janssen, Ben J.A, De Mey, Jo G.R

“…Slow dissociation of endothelin 1 from its endothelin A receptors is responsible for the long-lasting vasoconstrictor effects of the peptide. We showed…”
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Irreversible renal damage after transient renin-angiotensin system stimulation: involvement of an AT1-receptor mediated immune response by Heijnen, Bart F J, Nelissen, Jelly, van Essen, Helma, Fazzi, Gregorio E, Cohen Tervaert, Jan W, Peutz-Kootstra, Carine J, Mullins, John J, Schalkwijk, Casper G, Janssen, Ben J A, Struijker-Boudier, Harry A J

“…Transient activation of the renin-angiotensin system (RAS) induces irreversible renal damage causing sustained elevation in blood pressure (BP) in Cyp1a1-Ren2…”
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Impaired flow-induced arterial remodeling in DOCA-salt hypertensive rats by Lemkens, Pieter, Nelissen, Jelly, Meens, Merlijn J P M T, Fazzi, Gregorio E, Janssen, Ger J M, Debets, Jacques J M, Janssen, Ben J A, Schiffers, Paul M H, De Mey, Jo G R

“…Arteries from young healthy animals respond to chronic changes in blood flow and blood pressure by structural remodeling. We tested whether the ability to…”
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Antihypertensive treatment differentially affects vascular sphingolipid biology in spontaneously hypertensive rats by Spijkers, Léon J A, Janssen, Ben J A, Nelissen, Jelly, Meens, Merlijn J P M T, Wijesinghe, Dayanjan, Chalfant, Charles E, De Mey, Jo G R, Alewijnse, Astrid E, Peters, Stephan L M

“…We have previously shown that essential hypertension in humans and spontaneously hypertensive rats (SHR), is associated with increased levels of ceramide and…”
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Endothelin‐1 and Calcitonin Gene‐Related Peptide contribute to the developing hypertension in young spontaneously hypertensive rats by Nelissen, Jelly, Heijnen, Bart, Lemkens, Pieter, Debets, Jacques, Essen, Helma, Bost, Jet, Schiffers, Paul, De Mey, Jo, Janssen, Ben

“…Introduction binding of endothelin‐1 (ET‐1) to ETA‐receptors promotes hypertension and can be terminated selectively by calcitonin gene‐related peptide (CGRP)…”
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Dual neural peptidase/endothelin-converting enzyme inhibition improves endothelial function in mesenteric resistance arteries of young spontaneously hypertensive rats by Lemkens, Pieter, Nelissen, Jelly, Meens, Merlijn J.P.M.T, Janssen, Ben J.A, Schiffers, Paul M.H, De Mey, Jo G.R

“…BACKGROUND:Endothelin-1 (ET1) is a potent vasoconstrictor peptide with pro-mitogenic and pro-inflammatory properties and is therefore of interest in the…”
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Dual ECE/NEP inhibition and ETA/B receptor antagonists: Two ways of inhibiting endogenous ET‐1 effects in resistance arteries by Lemkens, Pieter, Nelissen, Jelly, Meens, Merlijn JPMT, Bost, Jet GP, Janssen, Ben JA, Schiffers, Paul MH, De Mey, Jo GR

“…Endothelin‐1 (ET‐1), a 21 amino acid peptide, can be formed by endothelin converting enzyme (ECE) and neutral endopeptidases (NEP). The DOCA‐salt hypertension…”
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CGRP terminates vasopressor responses to endothelin‐1 in vivo by Meens, Merlijn JPMT, Nelissen, Jelly, Mattheij, Nadine JA, Steinbusch, Laura KM, Janssen, Ben JA, De Mey, Jo GR

“…Introduction Endothelin‐1 (ET‐1) activates ETA and ETB receptors. In rat mesenteric arteries ETA activation causes long‐lasting contractions that are not ended…”
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Endothelin‐1 and the Metalloproteases ECE and NEP in DOCA‐Salt Hypertensive Rats by Nelissen, Jelly, Lemkens, Pieter, Debets, Jacques, Essen, Helma, Bost, Jet, Schiffers, Paul, De Mey, Jo, Janssen, Ben

“…Endothelin‐1 (ET‐1) is thought to be a key player in DOCA‐salt induced hypertension. We hypothesized that the bioavailability of ET‐1 is controlled by tissue…”
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Arterial Function and Flow Related Arterial Remodeling during DOCA‐salt Hypertension by Lemkens, Pieter, Nelissen, Jelly, Fazzi, Gregorio E., Janssen, Ben J., De Mey, Jo G.R., Schiffers, Paul M.H.

“…Hypothesis The DOCA‐salt Hypertensive rat (DOCA), a model of enhanced function of endothelin‐1 (ET‐1), displays: 1. Increased importance of endogenous ET‐1 in…”
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Dual neural endopeptidase/endothelin-converting [corrected] enzyme inhibition improves endothelial function in mesenteric resistance arteries of young spontaneously hypertensive rats by Lemkens, Pieter, Nelissen, Jelly, Meens, Merlijn J P M T, Janssen, Ben J A, Schiffers, Paul M H, De Mey, Jo G R

“…Endothelin-1 (ET1) is a potent vasoconstrictor peptide with pro-mitogenic and pro-inflammatory properties and is therefore of interest in the development of…”
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