Search Results - "Nejtek, Vicki A"
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Premature cognitive decline in specific domains found in young veterans with mTBI coincide with elder normative scores and advanced-age subjects with early-stage Parkinson's disease
Published in PloS one (17-11-2021)“…Epidemiologists report a 56% increased risk of veterans with (+) mild traumatic brain injury (mTBI) developing Parkinson's disease (PD) within 12-years…”
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PINK1 knockout rats show premotor cognitive deficits measured through a complex maze
Published in Frontiers in neuroscience (16-05-2024)“…Cognitive decline in Parkinson's disease (PD) is a critical premotor sign that may occur in approximately 40% of PD patients up to 10 years prior to clinical…”
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A pilot mobile integrated healthcare program for frequent utilizers of emergency department services
Published in The American journal of emergency medicine (01-11-2017)“…Abstract Purpose To examine whether or not a mobile integrated health (MIH) program may improve health-related quality of life while reducing emergency…”
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Aging-related limit of exercise efficacy on motor decline
Published in PloS one (27-11-2017)“…Identifying lifestyle strategies and allied neurobiological mechanisms that reduce aging-related motor impairment is imperative, given the accelerating number…”
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The Role of Charity Care and Primary Care Physician Assignment on ED Use in Homeless Patients
Published in The American journal of emergency medicine (01-08-2015)“…Abstract Objective Homeless patients are a vulnerable population with a higher incidence of using the emergency department (ED) for noncrisis care. Multiple…”
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Homelessness and ED use: myths and facts- the author's reply
Published in The American journal of emergency medicine (01-02-2016)“…[...]questions include the following: (1) where do ill homeless patients go for after-hour nonemergency care and (2) does it make more sense for shelters to…”
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Aging accelerates locomotor decline in PINK1 knockout rats in association with decreased nigral, but not striatal, dopamine and tyrosine hydroxylase expression
Published in Experimental neurology (01-06-2024)“…Parkinson's disease (PD) rodent models provide insight into the relationship between nigrostriatal dopamine (DA) signaling and locomotor function. Although…”
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Nigral-specific increase in ser31 phosphorylation compensates for tyrosine hydroxylase protein and nigrostriatal neuron loss: Implications for delaying parkinsonian signs
Published in Experimental neurology (01-10-2023)“…Compensatory mechanisms that augment dopamine (DA) signaling are thought to mitigate onset of hypokinesia prior to major loss of tyrosine hydroxylase (TH) in…”
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Moderate intensity aerobic exercise alleviates motor deficits in 6-OHDA lesioned rats and reduces serum levels of biomarkers of Parkinson's disease severity without recovery of striatal dopamine or tyrosine hydroxylase
Published in Experimental neurology (01-09-2024)“…Alleviation of motor impairment by aerobic exercise (AE) in Parkinson's disease (PD) patients points to activation of neurobiological mechanisms that may be…”
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Prolonged increase in ser31 tyrosine hydroxylase phosphorylation in substantia nigra following cessation of chronic methamphetamine
Published in Neurotoxicology (Park Forest South) (01-07-2018)“…•Previous methamphetamine exposure reduced tyrosine hydroxylase expression.•Tyrosine hydroxylase expression was reduced only in somatodendritic…”
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Differential expression of RET and GDNF family receptor, GFR-α1, between striatum and substantia nigra following nigrostriatal lesion: A case for diminished GDNF-signaling
Published in Experimental neurology (01-08-2023)“…Although glial cell line-derived neurotrophic factor (GDNF) showed efficacy in preclinical and early clinical studies to alleviate parkinsonian signs in…”
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Adolescent mental health: Challenges with maternal noncompliance
Published in Neuropsychiatric disease and treatment (01-01-2010)“…The leading cause of suicide ideation, attempts, and completion in adolescents is persistent and unresolved parental conflict. National statistics show…”
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Iowa Gambling Task scores predict future drug use in bipolar disorder outpatients with stimulant dependence
Published in Psychiatry research (30-12-2013)“…Abstract Poor decision-making is associated with poor recovery in persons with bipolar disorder and drug relapse in persons with stimulant dependence…”
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Establishing Equivalent Aerobic Exercise Parameters Between Early-Stage Parkinson's Disease and Pink1 Knockout Rats
Published in Journal of Parkinson's disease (01-01-2022)“…Rodent Parkinson's disease (PD) models are valuable to interrogate neurobiological mechanisms of exercise that mitigate motor impairment. Translating these…”
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Roles of disease severity and post-discharge outpatient visits as predictors of hospital readmissions
Published in BMC health services research (10-10-2016)“…Risks prediction models of 30-day all-cause hospital readmissions are multi-factorial. Severity of illness (SOI) and risk of mortality (ROM) categorized by All…”
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Do Atypical Antipsychotics Effectively Treat Co-Occurring Bipolar Disorder and Stimulant Dependence? A Randomized, Double-Blind Trial
Published in The journal of clinical psychiatry (01-08-2008)“…The primary objective was to compare the efficacy and tolerability of quetiapine and risperidone in the treatment of mood symptoms, drug cravings, and drug use…”
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GFR-α1 Expression in Substantia Nigra Increases Bilaterally Following Unilateral Striatal GDNF in Aged Rats and Attenuates Nigral Tyrosine Hydroxylase Loss Following 6‑OHDA Nigrostriatal Lesion
Published in ACS chemical neuroscience (16-10-2019)“…Glial cell line-derived neurotrophic factor (GDNF) improved motor function in Parkinson’s disease (PD) patients in Phase I clinical trials, and these effects…”
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Race- and gender-related differences in clinical characteristics and quality of life among outpatients with psychotic disorders
Published in Journal of psychiatric practice (01-09-2012)“…Historically, the literature suggests that African Americans with mental illness are diagnosed with psychotic disorders at a higher rate and receive higher…”
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High and low emotion events influence emotional stress perceptions and are associated with salivary cortisol response changes in a consecutive stress paradigm
Published in Psychoneuroendocrinology (01-04-2002)“…Numerous studies over the last few decades have successfully utilized “psychological” stressors to examine stress-induced cortisol release as a function of the…”
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