Search Results - "Nejime, Namie"

Chronic Production of Peroxynitrite in the Vascular Wall Impairs Vasorelaxation Function in SHR/NDmcr-cp Rats, an Animal Model of Metabolic Syndrome by Kagota, Satomi, Tada, Yukari, Nejime, Namie, Nakamura, Kazuki, Kunitomo, Masaru, Shinozuka, Kazumasa

“…We have previously reported that peroxynitrite is involved in dysfunction of nitric oxide (NO)-mediated vasorelaxation in SHR/NDmcr-cp rats (SHR-cp), which…”
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Effects of ATP on the Intracellular Calcium Level in the Osteoblastic TBR31-2 Cell Line by Nishii, Naomi, Nejime, Namie, Yamauchi, Chisako, Yanai, Nobuaki, Shinozuka, Kazumasa, Nakabayashi, Toshikatsu

“…We investigated the effects of extracellular ATP on TBR31-2 cells established from the bone marrow of transgenic mice harboring the temperature-sensitive…”
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Highly Sensitive Measurement of P-Glycoprotein-Mediated Transport Activity in Caco-2 Cells by Wakuda, Hirokazu, Nejime, Namie, Tada, Yukari, Kagota, Satomi, Umegaki, Keizo, Yamada, Shizuo, Shinozuka, Kazumasa

“…We established a highly sensitive method for evaluating P-glycoprotein activity in Caco-2 cells. Using time-lapse confocal laser-scanning microscopy, we…”
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Effect of Vanadate on ATP-Induced Increase in Intracellular Calcium Ion Levels in Human Umbilical Vein Endothelial Cells by Nejime, Namie, Tada, Yukari, Kagota, Satomi, Kubota, Yoko, Shibuichi, Ikuo, Shinoda, Yuki, Yamamoto, Tomohiro, Watanabe, Yasuo, Shinozuka, Kazumasa

“…We investigated the effect of ammonium vanadate (vanadate) on ATP-induced increases in intracellular calcium ion level ([Ca2+]i) of human umbilical vein…”
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Long-Term Feeding of Ginkgo biloba Extract Impairs Peripheral Circulation and Hepatic Function in Aged Spontaneously Hypertensive Rats by Tada, Yukari, Kagota, Satomi, Kubota, Yoko, Nejime, Namie, Nakamura, Kazuki, Kunitomo, Masaru, Shinozuka, Kazumasa

“…We previously demonstrated that Ginkgo biloba extract (GBE) produces an anti-hypertensive effect via enhanced vasodilation responses in young spontaneously…”
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Peroxynitrite is Involved in the Dysfunction of Vasorelaxation in SHR/NDmcr-cp Rats, Spontaneously Hypertensive Obese Rats by Kagota, Satomi, Tada, Yukari, Kubota, Yoko, Nejime, Namie, Yamaguchi, Yu, Nakamura, Kazuki, Kunitomo, Masaru, Shinozuka, Kazumasa

“…SHR/NDmcr-cp (SHR-cp) rats display typical symptoms and features of the metabolic syndrome. We previously reported that endothelium-dependent relaxation…”
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Disturbances in nitric oxide/cyclic guanosine monophosphate system in SHR/NDmcr-cp rats, a model of metabolic syndrome by Kagota, Satomi, Yamaguchi, Yu, Tanaka, Naoko, Kubota, Yoko, Kobayashi, Kyoko, Nejime, Namie, Nakamura, Kazuki, Kunitomo, Masaru, Shinozuka, Kazumasa

“…Metabolic syndrome is a cluster of metabolic abnormalities, including hypertension, hyperlipidemia, hyperinsulinemia, glucose intolerance and obesity. In such…”
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A novel method using confocal laser scanning microscopy for sensitive measurement of P-glycoprotein-mediated transport activity in Caco-2 cells by Wakuda, Hirokazu, Nejime, Namie, Tada, Yukari, Kagota, Satomi, Fahmi, Odette A., Umegaki, Keizo, Yamada, Shizuo, Shinozuka, Kazumasa

“…Objectives  The aim of this study was to use time‐lapse confocal laser scanning microscopy to establish a more sensitive and specific method for evaluating…”
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Characterization of Cardiac Size and Function in SHRSP.Z-Leprfa/IzmDmcr Rats, a New Animal Model of Metabolic Syndrome by Tada, Yukari, Kagota, Satomi, Matsumoto, Mika, Naito, Yoshiro, Shibata, Hiromi, Nejime, Namie, Tsujino, Takeshi, Koshiba, Masahiro, Masuyama, Tohru, Shinozuka, Kazumasa

“…Cardiac structural and functional abnormalities are observed in metabolic syndrome. However, such changes have not been investigated in the…”
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POSSIBLE PARTICIPATION OF CHLORIDE ION CHANNELS IN ATP RELEASE FROM CANCER CELLS IN SUSPENSION by Nejime, Namie, Kagota, Satomi, Tada, Yukari, Nakamura, Kazuki, Hashimoto, Michio, Kunitomo, Masaru, Shinozuka, Kazumasa

“…SUMMARY 1 Cancer cells must detach from the primary focus to initiate the process of metastasis. Previously, we demonstrated that intracellular Ca2+ levels are…”
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P2Y Receptor-Mediated Ca2+ Signaling Increases Human Vascular Endothelial Cell Permeability by Tanaka, Naoko, Kawasaki, Kumiko, Nejime, Namie, Kubota, Yoko, Nakamura, Kazuki, Kunitomo, Masaru, Takahashi, Koichi, Hashimoto, Michio, Shinozuka, Kazumasa

“…We investigated the effects of P2-receptor agonists on cell size, intracellular calcium levels ([Ca2+]i), and permeation of FITC-labeled dextran (FD-4) as well…”
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Effect of P2 receptor on the intracellular calcium increase by cancer cells in human umbilical vein endothelial cells by Nejime, Namie, Tanaka, Naoko, Yoshihara, Ryoko, Kagota, Satomi, Yoshikawa, Noriko, Nakamura, Kazuki, Kunitomo, Masaru, Hashimoto, Michio, Shinozuka, Kazumasa

“…One of the important functions of vascular endothelial cells is as a barrier between blood and vascular tissue. This led us to speculate that cancer cells…”
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ATP participates in the regulation of microvessel permeability by Tanaka, Naoko, Nejime, Namie, Kagota, Satomi, Kubota, Yoko, Yudo, Keiko, Nakamura, Kazuki, Kunitomo, Masaru, Shinozuka, Kazumasa, Takahashi, Koichi, Hashimoto, Michio

“…We demonstrated previously that stimulation of the P2Y receptor enhanced the macromolecular permeability of cultured endothelial cell monolayers via the…”
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DYSFUNCTION OF PURINERGIC REGULATION OF SYMPATHETIC NEUROTRANSMISSION IN SHR/NDMCR-CP (SHR-CP) RAT by Tanaka, Naoko, Nejime, Namie, Kagota, Satomi, Kubota, Yoko, Nakamura, Kazuki, Kunitomo, Masaru, Hashimoto, Michio, Yamamoto, Ryuichi, Shinozuka, Kazumasa

“…SUMMARY 1. The effect of 2‐chloroadenosine (2CA), a P1 receptor agonist and β,γ‐methylene ATP (βγmATP), a P2 receptor agonist, on the overflow of endogenous…”
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Coronary vascular dysfunction promoted by oxidative-nitrative stress in SHRSP.Z-Lepr(fa) /IzmDmcr rats with metabolic syndrome by Kagota, Satomi, Fukushima, Kazuhito, Umetani, Keiji, Tada, Yukari, Nejime, Namie, Nakamura, Kazuki, Mori, Hidezo, Sugimura, Kazuro, Kunitomo, Masaru, Shinozuka, Kazumasa

“…1. Metabolic syndrome is an independent risk factor for cardiovascular disease. SHRSP.Z-Lepr(fa) /IzmDmcr (SHRSP fatty) rat, established as a new rat model of…”
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Coronary vascular dysfunction promoted by oxidative-nitrative stress in SHRSP.Z-Leprfa/IzmDmcr rats with metabolic syndrome by Kagota, Satomi, Fukushima, Kazuhito, Umetani, Keiji, Tada, Yukari, Nejime, Namie, Nakamura, Kazuki, Mori, Hidezo, Sugimura, Kazuro, Kunitomo, Masaru, Shinozuka, Kazumasa

“…Summary 1. Metabolic syndrome is an independent risk factor for cardiovascular disease. SHRSP.Z‐Leprfa/IzmDmcr (SHRSP fatty) rat, established as a new rat…”
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Telmisartan provides protection against development of impaired vasodilation independently of metabolic effects in SHRSP.Z-Lepr(fa)/IzmDmcr rats with metabolic syndrome by Kagota, Satomi, Tada, Yukari, Nejime, Namie, Nakamura, Kazuki, Kunitomo, Masaru, Shinozuka, Kazumasa

“…Metabolic syndrome is known to facilitate the development of cardiovascular disease. We have demonstrated that mesenteric arteries of SHRSP.Z-Lepr(fa)/IzmDmcr…”
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Characterization of cardiac size and function in SHRSP.Z-Lepr(fa)/IzmDmcr rats, a new animal model of metabolic syndrome by Tada, Yukari, Kagota, Satomi, Matsumoto, Mika, Naito, Yoshiro, Shibata, Hiromi, Nejime, Namie, Tsujino, Takeshi, Koshiba, Masahiro, Masuyama, Tohru, Shinozuka, Kazumasa

“…Cardiac structural and functional abnormalities are observed in metabolic syndrome. However, such changes have not been investigated in the…”
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Effects of nicorandil on sympathetic neurotransmission in rat caudal artery by Tei, Ami, Nejime, Namie, Tada, Yukari, Kagota, Satomi, Tanabe, Yoko, Hashimoto, Michio, Shinozuka, Kazumasa

“…Summary 1. We examined the effects of nicorandil, an ATP‐sensitive potassium (KATP) channel opener and nitric oxide donor, on the release of noradrenaline from…”
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Coronary vascular dysfunction promoted by oxidative‐nitrative stress in SHRSP.Z‐Lepr fa /IzmDmcr rats with metabolic syndrome by Kagota, Satomi, Fukushima, Kazuhito, Umetani, Keiji, Tada, Yukari, Nejime, Namie, Nakamura, Kazuki, Mori, Hidezo, Sugimura, Kazuro, Kunitomo, Masaru, Shinozuka, Kazumasa

“…1. Metabolic syndrome is an independent risk factor for cardiovascular disease. SHRSP.Z‐Lepr fa /IzmDmcr (SHRSP fatty) rat, established as a new rat model of…”
Get full text