Search Results - "Neitzel, R R"

Analysis of e-waste recycling behavior based on survey at a Midwestern US University by Arain, A.L., Pummill, R., Adu-Brimpong, J., Becker, S., Green, M., Ilardi, M., Van Dam, E., Neitzel, R.L.

“…•Consumer behaviors are critical to managing and reducing e-waste.•Faculty, students, and staff at a Midwestern University surveyed regarding e-waste.•Cost,…”
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The MAPK Pathway Regulates Intrinsic Resistance to BET Inhibitors in Colorectal Cancer by Ma, Yufang, Wang, Lihong, Neitzel, Leif R, Loganathan, Sudan N, Tang, Nan, Qin, Lili, Crispi, Emily E, Guo, Yan, Knapp, Stefan, Beauchamp, R Daniel, Lee, Ethan, Wang, Jialiang

“…The bromodomain and extra-terminal domain (BET) family proteins are epigenetic readers for acetylated histone marks. Emerging BET bromodomain inhibitors have…”
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Inhibition of GPR68 kills glioblastoma in zebrafish xenograft models by Neitzel, Leif R, Fuller, Daniela T, Williams, Charles H, Hong, Charles C

“…Inhibition and knockdown of GPR68 negatively affects glioblastoma cell survival in vitro by inducing ferroptosis. Herein, we aimed to demonstrate that…”
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The Small Molecule IMR-1 Inhibits the Notch Transcriptional Activation Complex to Suppress Tumorigenesis by Astudillo, Luisana, Da Silva, Thiago G, Wang, Zhiqiang, Han, Xiaoqing, Jin, Ke, VanWye, Jeffrey, Zhu, Xiaoxia, Weaver, Kelly, Oashi, Taiji, Lopes, Pedro E M, Orton, Darren, Neitzel, Leif R, Lee, Ethan, Landgraf, Ralf, Robbins, David J, MacKerell, Jr, Alexander D, Capobianco, Anthony J

“…In many cancers, aberrant Notch activity has been demonstrated to play a role in the initiation and maintenance of the neoplastic phenotype and in cancer stem…”
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The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling by Shen, Chen, Nayak, Anmada, Neitzel, Leif R., Adams, Amber A., Silver-Isenstadt, Maya, Sawyer, Leah M., Benchabane, Hassina, Wang, Huilan, Bunnag, Nawat, Li, Bin, Wynn, Daniel T., Yang, Fan, Garcia-Contreras, Marta, Williams, Charles H., Dakshanamurthy, Sivanesan, Hong, Charles C., Ayad, Nagi G., Capobianco, Anthony J., Ahmed, Yashi, Lee, Ethan, Robbins, David J.

“…Immunomodulatory drugs (IMiDs) are important for the treatment of multiple myeloma and myelodysplastic syndrome. Binding of IMiDs to Cereblon (CRBN), the…”
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Asbestos-containing materials in abandoned residential dwellings in Detroit by Franzblau, A., Demond, A.H., Sayler, S.K., D'Arcy, H., Neitzel, R.L.

“…The efforts of many municipalities to demolish abandoned residential dwellings (ARDs) are hampered by the presence of asbestos-containing materials (ACMs) in…”
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The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling by Ng, Victoria H., Spencer, Zachary, Neitzel, Leif R., Nayak, Anmada, Loberg, Matthew A., Shen, Chen, Kassel, Sara N., Kroh, Heather K., An, Zhenyi, Anthony, Christin C., Bryant, Jamal M., Lawson, Amanda, Goldsmith, Lily, Benchabane, Hassina, Hansen, Amanda G., Li, Jingjing, D’Souza, Starina, Lebensohn, Andres M., Rohatgi, Rajat, Weiss, William A., Weiss, Vivian L., Williams, Charles, Hong, Charles C., Robbins, David J., Ahmed, Yashi, Lee, Ethan

“…The relative abundance of Wnt receptors plays a crucial role in controlling Wnt signaling in tissue homeostasis and human disease. While the ubiquitin ligases…”
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Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling by Lebensohn, Andres M, Dubey, Ramin, Neitzel, Leif R, Tacchelly-Benites, Ofelia, Yang, Eungi, Marceau, Caleb D, Davis, Eric M, Patel, Bhaven B, Bahrami-Nejad, Zahra, Travaglini, Kyle J, Ahmed, Yashi, Lee, Ethan, Carette, Jan E, Rohatgi, Rajat

“…The comprehensive understanding of cellular signaling pathways remains a challenge due to multiple layers of regulation that may become evident only when the…”
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The Role of Bone Morphogenetic Protein Signaling in Non-Alcoholic Fatty Liver Disease by Thayer, Timothy E., Lino Cardenas, Christian L., Martyn, Trejeeve, Nicholson, Christopher J., Traeger, Lisa, Wunderer, Florian, Slocum, Charles, Sigurslid, Haakon, Shakartzi, Hannah R., O’Rourke, Caitlin, Shelton, Georgia, Buswell, Mary D., Barnes, Hanna, Neitzel, Leif R., Ledsky, Clara D., Li, Jason Pingcheng, Burke, Megan F., Farber-Eger, Eric, Perrien, Daniel S., Kumar, Ravindra, Corey, Kathleen E., Wells, Quinn S., Bloch, Kenneth D., Hong, Charles C., Bloch, Donald B., Malhotra, Rajeev

“…Non-alcoholic fatty liver disease (NAFLD) affects over 30% of adults in the United States. Bone morphogenetic protein (BMP) signaling is known to contribute to…”
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GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment by Williams, Charles H, Neitzel, Leif R, Cornell, Jessica, Rea, Samantha, Mills, Ian, Silver, Maya S, Ahmad, Jovanni D, Birukov, Konstantin G, Birukova, Anna, Brem, Henry, Tyler, Betty, Bar, Eli E, Hong, Charles C

“…Glioblastoma multiforme (GBM) stands as a formidable challenge in oncology because of its aggressive nature and severely limited treatment options. Despite…”
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Development of a Job Exposure Matrix for Noise in the Swedish Soft Tissue Paper Industry by Lee Neitzel, Richard, Andersson, Marianne, Eriksson, Helena, Torén, Kjell, Andersson, Eva

“…Abstract Objectives Noise exposure is a common occupational hazard, but has not been sufficiently characterized in paper mills. We developed a job-exposure…”
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Fatal Diabetic Ketoacidosis and Antipsychotic Medication by Ely, Susan F., Neitzel, Amber R., Gill, James R.

“…Hyperglycemia and new onset diabetes have been described with certain antipsychotic medications and some of the initial presentations are fatal diabetic…”
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Prospective noise induced changes to hearing among construction industry apprentices by Seixas, N S, Goldman, B, Sheppard, L, Neitzel, R, Norton, S, Kujawa, S G

“…Aims: To characterise the development of noise induced damage to hearing. Methods: Hearing and noise exposure were prospectively monitored among a cohort of…”
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Identification of a Paralog-Specific Notch1 Intracellular Domain Degron by Broadus, Matthew R., Chen, Tony W., Neitzel, Leif R., Ng, Victoria H., Jodoin, Jeanne N., Lee, Laura A., Salic, Adrian, Robbins, David J., Capobianco, Anthony J., Patton, James G., Huppert, Stacey S., Lee, Ethan

“…Upon Notch pathway activation, the receptor is cleaved to release the Notch intracellular domain (NICD), which translocates to the nucleus to activate gene…”
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Pilot task-based assessment of noise levels among firefighters by Neitzel, R.L., Hong, O., Quinlan, P., Hulea, R.

“…Over one million American firefighters are routinely exposed to various occupational hazards. While efforts have been made to identify and reduce some causes…”
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Methods for evaluating temporal trends in noise exposure by Neitzel, R. L., Galusha, D., Dixon-Ernst, C., Rabinowitz, P. M.

“…Abstract Objective: Hearing conservation programs have been mandatory in many US industries since 1983. Since then, three program elements (audiometric…”
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Short communication: genetic evaluation of mobility for Brown Swiss dairy cattle by Wright, J R, Wiggans, G R, Muenzenberger, C J, Neitzel, R R

“…Genetic parameters were estimated for mobility score and 16 linear type traits of Brown Swiss dairy cattle. Mobility is an overall assessment trait that…”
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Characterization of a cdc14 null allele in Drosophila melanogaster by Neitzel, Leif R, Broadus, Matthew R, Zhang, Nailing, Sawyer, Leah, Wallace, Heather A, Merkle, Julie A, Jodoin, Jeanne N, Sitaram, Poojitha, Crispi, Emily E, Rork, William, Lee, Laura A, Pan, Duojia, Gould, Kathleen L, Page-McCaw, Andrea, Lee, Ethan

“…Cdc14 is an evolutionarily conserved serine/threonine phosphatase. Originally identified in as a cell cycle regulator, its role in other eukaryotic organisms…”
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Evaluation and Comparison of Three Exposure Assessment Techniques by Neitzel, R. L., Daniell, W. E., Sheppard, L., Davies, H. W., Seixas, N. S.

“…This study was conducted to verify the performance of a recently developed subjective rating (SR) exposure assessment technique and to compare estimates made…”
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Safety and Health Hazard Observations in Hmong Farming Operations by Neitzel, R. L., Krenz, J., de Castro, A. B.

“…Agricultural workers have a high risk of occupational injuries, illnesses, and fatalities. However, there are very few standardized tools available to assess…”
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