Search Results - "Neilson, E. G."

A mouse model for polycystic kidney disease through a somatic in-frame deletion in the 5′ end of Pkd1 by Starremans, P.G., Li, X., Finnerty, P.E., Guo, L., Takakura, A., Neilson, E.G., Zhou, J.

“…Autosomal dominant polycystic kidney disease, a leading cause of end-stage renal disease in adults, is characterized by progressive focal cyst formation in the…”
Get full text

Angiotensin II stimulates the proliferation and biosynthesis of type I collagen in cultured murine mesangial cells by Wolf, G, Haberstroh, U, Neilson, EG

“…A murine mesangial cell line (MMC) was established from the glomeruli of SJL mice to study the influence of angiotensin II (ANG II) on their growth and…”
Get full text

Identification and Characterization of a Fibroblast Marker: FSP1 by Strutz, Frank, Okada, Hirokazu, Lo, Cecilia W., Danoff, Theodore, Carone, Robert L., Tomaszewski, John E., Neilson, Eric G.

“…We performed subtractive and differential hybridization for transcript comparison between murine fibroblasts and isogenic epithelium, and observed only a few…”
Get full text

Isoform switching of type IV collagen is developmentally arrested in X-linked Alport syndrome leading to increased susceptibility of renal basement membranes to endoproteolysis by Kalluri, R, Shield, C F, Todd, P, Hudson, B G, Neilson, E G

“…Normal glomerular capillaries filter plasma through a basement membrane (GBM) rich in alpha3(IV), alpha4(IV), and alpha5(IV) chains of type IV collagen. We now…”
Get full text

KAP-1, a novel corepressor for the highly conserved KRAB repression domain by Friedman, J R, Fredericks, W J, Jensen, D E, Speicher, D W, Huang, X P, Neilson, E G, Rauscher, 3rd, F J

“…The KRAB repression domain is one of the most widely distributed transcriptional effector domains yet identified, but its mechanism of repression is unknown…”
Get full text

Angiotensin II induces cellular hypertrophy in cultured murine proximal tubular cells by Wolf, G, Neilson, E G

“…In the present study we demonstrate that a murine proximal tubular cell line (MCT cells), expressing angiotensin II (ANG II) receptors [dissociation constant…”
Get full text

Progressive renal fibrosis in murine polycystic kidney disease: An immunohistochemical observation by Okada, Hirokazu, Ban, Shinichi, Nagao, Shizuko, Takahashi, Hisahide, Suzuki, Hiromichi, Neilson, Eric G.

“…Progressive renal fibrosis in murine polycystic kidney disease: An immunohistochemical observation. The appearance of interstitial fibrosis in polycystic…”
Get full text

Inhibition of Calcium Oxalate Crystal Growth in vitro by Uropontin: Another Member of the Aspartic Acid-Rich Protein Superfamily by Shiraga, H., Min, W., VanDusen, W. J., Clayman, M. D., Miner, D., Terrell, C. H., Sherbotie, J. R., Foreman, J. W., Przysiecki, C., Neilson, E. G., Hoyer, J. R.

“…The majority of human urinary stones are primarily composed of calcium salts. Although normal urine is frequently supersaturated with respect to calcium…”
Get full text

Epithelial—mesenchymal transformation of renal tubular epithelial cells in vitro and in vivo by Okada, H., Inoue, T., Suzuki, H., Strutz, F., Neilson, E. G.

Get full text

Expression of apoptosis regulatory proteins in tubular epithelium stressed in culture or following acute renal failure by Ortiz, Alberto, Lorz, Corina, Catalán, Marina P., Danoff, Theodore M., Yamasaki, Yasushi, Egido, Jesús, Neilson, Eric G.

“…Expression of apoptosis regulatory proteins in tubular epithelium stressed in culture or following acute renal failure. While tubular cell death is a…”
Get full text

Regulation of Fas and Fas ligand expression in cultured murine renal cells and in the kidney during endotoxemia by Ortiz-Arduan, A, Danoff, T M, Kalluri, R, González-Cuadrado, S, Karp, S L, Elkon, K, Egido, J, Neilson, E G

“…Fas ligand (FasL) and Fas belong to a recently described family of cytokines and receptors with similarities to tumor necrosis factor (TNF) and its receptors…”
Get full text

Pathogenesis and therapy of interstitial nephritis by Neilson, Eric G.

Get full text

TGF-β Signaling in Fibroblasts Modulates the Oncogenic Potential of Adjacent Epithelia by Bhowmick, Neil A., Chytil, Anna, Plieth, David, Gorska, Agnieszka E., Dumont, Nancy, Shappell, Scott, Washington, M. Kay, Neilson, Eric G., Moses, Harold L.

“…Stromal cells can have a significant impact on the carcinogenic process in adjacent epithelia. The role of transforming growth$factor-\beta$($TGF-\beta$)…”
Get full text

Characterization of a Renal Tubular Epithelial Cell Line Which Secretes the Autologous Target Antigen of Autoimmune Experimental Interstitial Nephritis by Haverty, Thomas P., Kelly, Carolyn J., Hines, William H., Amenta, Peter S., Watanabe, Melanie, Harper, Robert A., Kefalides, Nicholas A., Neilson, Eric G.

“…Proximal tubular epithelial cells from mice which develop autoimmune interstitial nephritis were found to express the nephritogenic target antigen, 3M-1…”
Get full text

Identification of the alpha 3 chain of type IV collagen as the common autoantigen in antibasement membrane disease and Goodpasture syndrome by Kalluri, R, Wilson, C B, Weber, M, Gunwar, S, Chonko, A M, Neilson, E G, Hudson, B G

“…Antiglomerular basement membrane (GBM) antibodies can cause glomerulonephritis or pulmonary hemorrhage by themselves or Goodpasture syndrome when they occur…”
Get full text

The role of lymphocytes in the progression of interstitial disease by Strutz, F, Neilson, E G

“…Chronic interstitial disease is a major cause of end-stage renal failure. The process is characterized mainly by tubular atrophy and interstitial fibrosis and…”
Get more information

Angiotensin II as a hypertrophogenic cytokine for proximal tubular cells by Wolf, G, Neilson, E G

Get more information

Attenuated expression of epithelial cell adhesion molecules in murine polycystic kidney disease by Rocco, M V, Neilson, E G, Hoyer, J R, Ziyadeh, F N

“…Polycystic kidney disease is an inherited disorder of parenchymal structure that leads to renal failure. Cysts begin as focal dilations in proximal tubules and…”
Get full text

Comparative distribution of the alpha 1(IV), alpha 5(IV), and alpha 6(IV) collagen chains in normal human adult and fetal tissues and in kidneys from X-linked Alport syndrome patients by Peissel, B, Geng, L, Kalluri, R, Kashtan, C, Rennke, H G, Gallo, G R, Yoshioka, K, Sun, M J, Hudson, B G, Neilson, E G

“…We have shown previously that the 5' ends of the genes for the alpha 5(IV) and alpha 6(IV) collagen chains lie head-to-head on Xq22 and are deleted in patients…”
Get full text

Loss of TGF-β type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-α-, MSP- and HGF-mediated signaling networks by CHENG, Nikki, BHOWMICK, Neil A, CHYTIL, Anna, GORKSA, Agnieszka E, BROWN, Kimberly A, MURAOKA, Rebecca, ARTEAGA, Carlos L, NEILSON, Eric G, HAYWARD, Simon W, MOSES, Harold L

“…Stromal fibroblasts regulate epithelial cell behavior through direct and indirect cell-cell interactions. To clarify the role of TGF-beta signaling in stromal…”
Get full text