Search Results - "Neild, Annie"
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Legionella Reveal Dendritic Cell Functions that Facilitate Selection of Antigens for MHC Class II Presentation
Published in Immunity (Cambridge, Mass.) (01-06-2003)“…To understand how adaptive immune responses are generated against bacteria that avoid being delivered to lysosomes, interactions between professional…”
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Journal Article -
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Kinetics and Cellular Origin of Cytokines in the Central Nervous System: Insight into Mechanisms of Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis
Published in The Journal of immunology (1950) (01-01-2000)“…Experimental autoimmune encephalomyelitis induced by myelin oligodendrocyte glycoprotein (MOG) in C57BL/6 (H-2b) mice is characterized by early (day 12) acute…”
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Immunity to vacuolar pathogens: What can we learn from Legionella?
Published in Cellular microbiology (01-11-2004)“…Summary Intracellular pathogens can manipulate host cellular pathways to create specialized organelles. These pathogen‐modified vacuoles permit the survival…”
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Activated Macrophages Infected with Legionella Inhibit T Cells by Means of MyD88-Dependent Production of Prostaglandins
Published in Journal of Immunology (15-12-2005)“…To understand how macrophages (Mphi) activated with IFN-gamma modulate the adaptive immune response to intracellular pathogens, the interaction of…”
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Journal Article -
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Processing and Major Histocompatibility Complex Class II Presentation of Legionella pneumophila Antigens by Infected Macrophages
Published in Infection and Immunity (01-04-2005)“…To better understand interactions between the intracellular pathogen Legionella pneumophila and macrophages (M[phi]s), host and bacterial determinants…”
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Guiding Dyslipidemia Treatment: A Population Pharmacokinetic–Pharmacodynamic Framework for Obicetrapib
Published in Journal of clinical pharmacology (01-09-2024)“…Obicetrapib is a selective inhibitor of cholesteryl ester transfer protein that is currently in phase 3 of development for the treatment of dyslipidemia as…”
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Obicetrapib on top of maximally tolerated lipid‐modifying therapies in participants with or at high risk for atherosclerotic cardiovascular disease: rationale and designs of BROADWAY and BROOKLYN
Published in The American heart journal (01-08-2024)“…Obicetrapib, a novel, selective cholesteryl ester transfer protein (CETP) inhibitor, reduces low-density lipoprotein cholesterol (LDL-C), LDL particles,…”
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Journal Article -
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Acquired immune responses following Legionella infection of antigen presenting cells
Published 01-01-2004“…Legionella are members of a class of pathogens that reside in non-degradative compartments within professional antigen presenting cells (APCs). The adaptive…”
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Dissertation