Search Results - "Neilan, John"

Adenovirus-vectored novel African Swine Fever Virus antigens elicit robust immune responses in swine by Lokhandwala, Shehnaz, Waghela, Suryakant D, Bray, Jocelyn, Sangewar, Neha, Charendoff, Chloe, Martin, Cameron L, Hassan, Wisam S, Koynarski, Tsvetoslav, Gabbert, Lindsay, Burrage, Thomas G, Brake, David, Neilan, John, Mwangi, Waithaka

“…African Swine Fever Virus (ASFV) is a high-consequence transboundary animal pathogen that often causes hemorrhagic disease in swine with a case fatality rate…”
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Comparative Evaluation of the Foot-and-Mouth Disease Virus Permissive LF-BK αVβ6 Cell Line for Senecavirus A Research by Mason, Jessica, Primavera, Victoria, Martignette, Lauren, Clark, Benjamin, Barrera, Jose, Simmons, Janine, Hurtle, William, Neilan, John G., Puckette, Michael

“…Senecavirus A (SVA) is a member of the family Picornaviridae and enzootic in domestic swine. SVA can induce vesicular lesions that are clinically…”
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Evaluation of DNA Vaccine Candidates against Foot-and-Mouth Disease Virus in Cattle by Puckette, Michael, Clark, Benjamin A, Barrera, José, Neilan, John G, Rasmussen, Max V

“…We evaluated four DNA vaccine candidates for their ability to produce virus-like particles (VLPs) and elicit a protective immune response against…”
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Plant‐made E2 glycoprotein single‐dose vaccine protects pigs against classical swine fever by Laughlin, Richard C., Madera, Rachel, Peres, Yair, Berquist, Brian R., Wang, Lihua, Buist, Sterling, Burakova, Yulia, Palle, Sreenath, Chung, Chungwon J., Rasmussen, Max V., Martel, Erica, Brake, David A., Neilan, John G., Lawhon, Sara D., Adams, L. Garry, Shi, Jishu, Marcel, Sylvain

“…Classical Swine Fever Virus (CSFV) causes classical swine fever, a highly contagious hemorrhagic fever affecting both feral and domesticated pigs. Outbreaks of…”
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Comparative Evaluation of the Foot-and-Mouth Disease Virus Permissive LF-BK α[sub.V]β[sub.6] Cell Line for Senecavirus A Research by Mason, Jessica, Primavera, Victoria, Ma, Clark, Benjamin, Barrera, Jose, Simmons, Janine, Hurtle, William, Neilan, John G, Puckette, Michael

“…Senecavirus A (SVA) is a member of the family Picornaviridae and enzootic in domestic swine. SVA can induce vesicular lesions that are clinically…”
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Transiently Transfected Mammalian Cell Cultures: An Adaptable and Effective Platform for Virus-like Particle-Based Vaccines against Foot-and-Mouth Disease Virus by Puckette, Michael, Primavera, Victoria, Martel, Erica, Barrera, Jose, Hurtle, William, Clark, Benjamin, Kamicker, Barbara, Zurita, Mariceny, Brake, David, Neilan, John

“…RNA viruses, such as foot-and-mouth disease virus (FMDV), have error-prone replication resulting in the continuous emergence of new viral strains capable of…”
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Generation and characterization of genetically stable heterohybridomas producing foot-and-mouth disease virus-specific porcine monoclonal antibodies by Puckette, Michael C., Martel, Erica, Rutherford, Jacob, Barrera, José, Hurtle, William, Pisano, Melia, Martignette, Lauren, Zurita, Mariceny, Neilan, John G., Chung, Chungwon J.

“…This report covers the methodology for generation of stable heterohybridoma clones producing Foot-and-mouth disease virus (FMDV) reactive porcine monoclonal…”
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Foot-and-Mouth Disease (FMD) Virus 3C Protease Mutant L127P: Implications for FMD Vaccine Development by Puckette, Michael, Clark, Benjamin A, Smith, Justin D, Turecek, Traci, Martel, Erica, Gabbert, Lindsay, Pisano, Melia, Hurtle, William, Pacheco, Juan M, Barrera, José, Neilan, John G, Rasmussen, Max

“…The foot-and-mouth disease virus (FMDV) afflicts livestock in more than 80 countries, limiting food production and global trade. Production of foot-and-mouth…”
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Effect of foot-and-mouth disease virus 3C protease B2 β-strand proline mutagenesis on expression and processing of the P1 polypeptide using a plasmid expression vector by Martel, Erica, Forzono, Emily, Kurker, Richard, Clark, Benjamin A, Neilan, John G, Puckette, Michael

“…The production of experimental molecular vaccines against foot-and-mouth disease virus utilizes the viral encoded 3C protease for processing of the P1…”
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Evaluation of Gaussia luciferase and foot-and-mouth disease virus 2A translational interrupter chimeras as polycistronic reporters for transgene expression by Puckette, Michael, Burrage, Thomas, Neilan, John G, Rasmussen, Max

“…The Gaussia princeps luciferase is used as a stand-alone reporter of transgene expression for in vitro and in vivo expression systems due to the rapid and easy…”
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Multiple efficacy studies of an adenovirus-vectored foot-and-mouth disease virus serotype A24 subunit vaccine in cattle using homologous challenge by Schutta, Christopher, Barrera, José, Pisano, Melia, Zsak, Laszlo, Grubman, Marvin J, Mayr, Gregory A, Moraes, Mauro P, Kamicker, Barbara J, Brake, David A, Ettyreddy, Damodar, Brough, Douglas E, Butman, Bryan T, Neilan, John G

“…Highlights • FMDV serotype A24 replication deficient adenovirus-vector vaccine was safe after IM dosing. • AdtA24 vaccine was immunogenic; antibody titers to…”
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Effect of Foot-and-Mouth Disease Virus 2B Viroporin on Expression and Extraction of Mammalian Cell Culture Produced Foot-and-Mouth Disease Virus-like Particles by Primavera, Victoria, Simmons, Janine, Clark, Benjamin A, Neilan, John G, Puckette, Michael

“…To improve the production of foot-and-mouth disease (FMD) molecular vaccines, we sought to understand the effects of the FMD virus (FMDV) 2B viroporin in an…”
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Versatility of the adenovirus-vectored foot-and-mouth disease vaccine platform across multiple foot-and-mouth disease virus serotypes and topotypes using a vaccine dose representative of the AdtA24 conditionally licensed vaccine by Barrera, José, Brake, David A., Schutta, Christopher, Ettyreddy, Damodar, Kamicker, Barbara J., Rasmussen, Max V., Bravo de Rueda, Carla, Zurita, Mariceny, Pisano, Melia, Hurtle, William, Brough, Douglas E., Butman, Bryan T., Harper, Bruce G., Neilan, John G.

“…•The AdtFMD vaccine platform is versatile for multiple FMDV serotypes and topotypes.•Cattle were immunized with one of 16 different AdtFMD monovalent…”
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Production of foot-and-mouth disease virus capsid proteins by the TEV protease by Puckette, Michael, Smith, Justin D., Gabbert, Lindsay, Schutta, Christopher, Barrera, José, Clark, Benjamin A., Neilan, John G., Rasmussen, Max

“…•Use of FMDV 2A sequence to produce TEVpro and substrate from a single ORF.•TEVpro processes a modified FMDV P1 polypeptide to produce FMDV capsid…”
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Use of ENABL® adjuvant to increase the potency of an adenovirus-vectored foot-and-mouth disease virus serotype A subunit vaccine by Barrera, José, Schutta, Christopher, Pisano, Melia, Grubman, Marvin J., Brake, David A., Miller, Timothy, Kamicker, Barbara J., Olutunmbi, Femi, Ettyreddy, Damodar, Brough, Douglas E., Butman, Bryan T., Neilan, John G.

“…•One dose of AdtA24 + adjuvant prevented clinical FMD at 7 and 14 dpv.•AdtA24 + adjuvant improved protection for FMD and viremia vs. a 4× AdtA24 dose…”
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Evaluation of modified Vaccinia Ankara-based vaccines against foot-and-mouth disease serotype A24 in cattle by Steigerwald, Robin, Brake, David A., Barrera, José, Schutta, Christopher J., Kalla, Markus, Wennier, Sonia T., Volkmann, Ariane, Hurtle, William, Clark, Benjamin A., Zurita, Mariceny, Pisano, Melia, Kamicker, Barbara J., Puckette, Michael C., Rasmussen, Max V., Neilan, John G.

“…•FMDV P1 and 3C expression levels optimized for vaccine production in CEF cells.•Correct FMDV P1 antigen expression and processing in bovine cells.•MVA-BN-FMD…”
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A pandemic strain of calicivirus threatens rabbit industries in the Americas by McIntosh, Michael T, Behan, Shawn C, Mohamed, Fawzi M, Lu, Zhiqiang, Moran, Karen E, Burrage, Thomas G, Neilan, John G, Ward, Gordon B, Botti, Giuliana, Capucci, Lorenzo, Metwally, Samia A

“…Rabbit Hemorrhagic Disease (RHD) is a severe acute viral disease specifically affecting the European rabbit Oryctolagus cuniculus. As the European rabbit is…”
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Efficacy of an adenovirus-vectored foot-and-mouth disease virus serotype A subunit vaccine in cattle using a direct contact transmission model by Neilan, John G, Schutta, Christopher, Barrera, José, Pisano, Melia, Zsak, Laszlo, Hartwig, Ethan, Rasmussen, Max V, Kamicker, Barbara J, Ettyreddy, Damodar, Brough, Douglas E, Butman, Bryan T, Brake, David A

“…A direct contact transmission challenge model was used to simulate natural foot-and-mouth disease virus (FMDV) spread from FMDV A24/Cruzeiro/BRA/55 infected…”
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Smart Card Decontamination in a High-Containment Laboratory by Gabbert, Lindsay R, Smith, Justin D, Neilan, John G, Ferman, Geoffrey S, Rasmussen, Max V

“…Validated procedures for decontamination of laboratory surfaces and equipment are essential to biosafety and biorisk programs at high-containment laboratories…”
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Phenotype-Based Identification of Host Genes Required for Replication of African Swine Fever Virus by Chang, Annie C Y, Zsak, Laszlo, Feng, Yanan, Mosseri, Ronen, Lu, Quan, Kowalski, Paul, Zsak, Aniko, Burrage, Thomas G, Neilan, John G, Kutish, Gerald F, Lu, Zhiqiang, Laegreid, Will, Rock, Daniel L, Cohen, Stanley N

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