Search Results - "Neil, Jason R."

Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling by Spangler, Jamie B., Neil, Jason R., Abramovitch, Sivan, Yarden, Yosef, White, Forest M., Lauffenburger, Douglas A., Wittrup, K. Dane, Kuriyan, John

“…Due to its common dysregulation in epithelial-based cancers and extensive characterization of its role in tumor growth, epidermal growth factor receptor (EGFR)…”
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Rapid MRSA detection via tandem mass spectrometry of the intact 80 kDa PBP2a resistance protein by Neil, Jason R., Verma, Arvind, Kronewitter, Scott R., McGee, William M., Mullen, Christopher, Viirtola, Marjaana, Kotovuori, Annika, Friedrich, Herdis, Finell, Johan, Rannisto, Joni, Syka, John E. P., Stephenson, James L.

“…Treatment of antibiotic-resistant infections is dependent on the detection of specific bacterial genes or proteins in clinical assays. Identification of…”
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Fibulins 3 and 5 antagonize tumor angiogenesis in vivo by ALBIG, Allan R, NEIL, Jason R, SCHIEMANN, William P

“…Lethal tumor growth and progression cannot occur without angiogenesis, which facilitates cancer cell proliferation, survival, and dissemination. Fibulins…”
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Direct detection of OXA-48-like carbapenemase variants with and without co-expression of an extended-spectrum β-lactamase from bacterial cell lysates using mass spectrometry by McGee, William M., Verma, Arvind, Viirtola, Marjaana, Kronewitter, Scott R., Neil, Jason R., Stephenson, James L.

“…•LC-MS methods are used to identify intact OXA-48 like enzymes from bacterial lysates.•Individual protein variants of the OXA-48 like carbapenemases can be…”
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Transforming growth factor-β and the hallmarks of cancer by Tian, Maozhen, Neil, Jason R., Schiemann, William P.

“…Tumorigenesis is in many respects a process of dysregulated cellular evolution that drives malignant cells to acquire six phenotypic hallmarks of cancer,…”
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Epidermal growth factor receptor downregulation by small heterodimeric binding proteins by Hackel, Benjamin J., Neil, Jason R., White, Forest M., Wittrup, K.Dane

“…No single engineered protein has been shown previously to robustly downregulate epidermal growth factor receptor (EGFR), a validated cancer target. A panel of…”
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Cox-2 inactivates Smad signaling and enhances EMT stimulated by TGF-β through a PGE2-dependent mechanisms by Neil, Jason R., Johnson, Kyle M., Nemenoff, Raphael A., Schiemann, William P.

“…Although it is well established that mammary tumorigenesis converts transforming growth factor-β (TGF-β) from a tumor suppressor to a tumor promoter, the…”
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Altered TAB1:IκB Kinase Interaction Promotes Transforming Growth Factor β-Mediated Nuclear Factor-κB Activation during Breast Cancer Progression by NEIL, Jason R, SCHIEMANN, William P

“…The conversion of transforming growth factor β (TGF-β) from a tumor suppressor to a tumor promoter occurs frequently during mammary tumorigenesis, yet the…”
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DrugMap: A quantitative pan-cancer analysis of cysteine ligandability by Takahashi, Mariko, Chong, Harrison B, Zhang, Siwen, Yang, Tzu-Yi, Lazarov, Matthew J, Harry, Stefan, Maynard, Michelle, Hilbert, Brendan, White, Ryan D, Murrey, Heather E, Tsou, Chih-Chiang, Vordermark, Kira, Assaad, Jonathan, Gohar, Magdy, Dürr, Benedikt R, Richter, Marianne, Patel, Himani, Kryukov, Gregory, Brooijmans, Natasja, Alghali, Aliyu Sidi Omar, Rubio, Karla, Villanueva, Antonio, Zhang, Junbing, Ge, Maolin, Makram, Farah, Griesshaber, Hanna, Harrison, Drew, Koglin, Ann-Sophie, Ojeda, Samuel, Karakyriakou, Barbara, Healy, Alexander, Popoola, George, Rachmin, Inbal, Khandelwal, Neha, Neil, Jason R, Tien, Pei-Chieh, Chen, Nicholas, Hosp, Tobias, van den Ouweland, Sanne, Hara, Toshiro, Bussema, Lillian, Dong, Rui, Shi, Lei, Rasmussen, Martin Q, Domingues, Ana Carolina, Lawless, Aleigha, Fang, Jacy, Yoda, Satoshi, Nguyen, Linh Phuong, Reeves, Sarah Marie, Wakefield, Farrah Nicole, Acker, Adam, Clark, Sarah Elizabeth, Dubash, Taronish, Kastanos, John, Oh, Eugene, Fisher, David E, Maheswaran, Shyamala, Haber, Daniel A, Boland, Genevieve M, Sade-Feldman, Moshe, Jenkins, Russell W, Hata, Aaron N, Bardeesy, Nabeel M, Suvà, Mario L, Martin, Brent R, Liau, Brian B, Ott, Christopher J, Rivera, Miguel N, Lawrence, Michael S, Bar-Peled, Liron

“…Cysteine-focused chemical proteomic platforms have accelerated the clinical development of covalent inhibitors for a wide range of targets in cancer. However,…”
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SPARC inhibits epithelial cell proliferation in part through stimulation of the transforming growth factor-beta-signaling system by Schiemann, Barbara J, Neil, Jason R, Schiemann, William P

“…Secreted protein, acidic and rich in cysteine (SPARC) is a multifunctional secreted protein that regulates cell-cell and cell-matrix interactions, leading to…”
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The use of cystatin C to inhibit epithelial-mesenchymal transition and morphological transformation stimulated by transforming growth factor-beta by Sokol, Jonathan P, Neil, Jason R, Schiemann, Barbara J, Schiemann, William P

“…Transforming growth factor-beta (TGF-beta) is a potent suppressor of mammary epithelial cell (MEC) proliferation and is thus an inhibitor of mammary tumor…”
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TGF-beta in cancer and other diseases by Neil, Jason R, Galliher, Amy J, Schiemann, William P

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Direct detection of intact Klebsiella pneumoniae carbapenemase variants from cell lysates: Identification, characterization and clinical implications by McGee, William M., Faron, Matthew L., Neil, Jason R., Kronewitter, Scott R., Buchan, Blake W., Ledeboer, Nathan A., Stephenson, James L.

“…•LC-MS methods are used to identify intact Klebsiella pneumoniae carbapenemase (KPC).•Mass spectrometry validates the mature form of KPC based on molecular…”
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X-linked Inhibitor of Apoptosis Protein and Its E3 Ligase Activity Promote Transforming Growth Factor-Β-mediated Nuclear Factor-κB Activation during Breast Cancer Progression by Neil, Jason R., Tian, Maozhen, Schiemann, William P.

“…The precise sequence of events that enable mammary tumorigenesis to convert transforming growth factor-Β (TGF-Β) from a tumor suppressor to a tumor promoter…”
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Transforming growth factor-[beta] and the hallmarks of cancer by Tian, Maozhen, Neil, Jason R, Schiemann, William P

“…Tumorigenesis is in many respects a process of dysregulated cellular evolution that drives malignant cells to acquire six phenotypic hallmarks of cancer,…”
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Altered TAB1:IKK Interaction Promotes TGF-β-Mediated NF-κB Activation During Breast Cancer Progression by Neil, Jason R., Schiemann, William P.

“…The conversion of TGF-β from a tumor suppressor to a tumor promoter occurs frequently during mammary tumorigenesis, yet the molecular mechanisms underlying…”
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X-linked Inhibitor of Apoptosis Protein and Its E3 Ligase Activity Promote Transforming Growth Factor-β-mediated Nuclear Factor-κB Activation during Breast Cancer Progression by Jason R. Neil, Maozhen Tian, William P. Schiemann

“…The precise sequence of events that enable mammary tumorigenesis to convert transforming growth factor-β (TGF-β) from a tumor suppressor to a tumor promoter…”
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X-linked inhibitor of apoptosis protein and its E3 ligase activity promote transforming growth factor-{beta}-mediated nuclear factor-{kappa}B activation during breast cancer progression by Neil, Jason R, Tian, Maozhen, Schiemann, William P

“…The precise sequence of events that enable mammary tumorigenesis to convert transforming growth factor-beta (TGF-beta) from a tumor suppressor to a tumor…”
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Cox-2 inactivates Smad signaling and enhances EMT stimulated by TGF-[beta] through a PGE[sub]2-dependent mechanisms by Neil, Jason R, Johnson, Kyle M, Nemenoff, Raphael A, Schiemann, William P

“…Although it is well established that mammary tumorigenesis converts transforming growth factor-β (TGF-β) from a tumor suppressor to a tumor promoter, the…”
Get full text

Role of transforming growth factor-beta in cancer progression by Galliher, Amy J, Neil, Jason R, Schiemann, William P

“…Invasion and metastasis are the most lethal characteristics of cancer and the leading causes of cancer-related death. Transforming growth factor (TGF)-beta is…”
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