Search Results - "Neidle, Ellen L"

A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion by Mallinson, Sam J. B., Machovina, Melodie M., Silveira, Rodrigo L., Garcia-Borràs, Marc, Gallup, Nathan, Johnson, Christopher W., Allen, Mark D., Skaf, Munir S., Crowley, Michael F., Neidle, Ellen L., Houk, Kendall N., Beckham, Gregg T., DuBois, Jennifer L., McGeehan, John E.

“…Microbial aromatic catabolism offers a promising approach to convert lignin, a vast source of renewable carbon, into useful products. Aryl- O -demethylation is…”
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Defying stereotypes: the elusive search for a universal model of LysR-type regulation by Momany, Cory, Neidle, Ellen L.

“…Summary LysR‐type transcriptional regulators (LTTRs) compose the largest family of homologous regulators in bacteria. Considering their prevalence, it is not…”
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Full-Length Structures of BenM and Two Variants Reveal Different Oligomerization Schemes for LysR-Type Transcriptional Regulators by Ruangprasert, Ajchareeya, Craven, Sarah H., Neidle, Ellen L., Momany, Cory

“…BenM, a LysR-type transcriptional regulator (LTTR) from the bacterium Acinetobacter baylyi, responds synergistically to benzoate and cis, cis-muconate. With…”
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Engineering CatM, a LysR-Type Transcriptional Regulator, to Respond Synergistically to Two Effectors by Tumen-Velasquez, Melissa P, Laniohan, Nicole S, Momany, Cory, Neidle, Ellen L

“…The simultaneous response of one transcriptional regulator to different effectors remains largely unexplored. Nevertheless, such interactions can substantially…”
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Gene amplification mutations originate prior to selective stress in Acinetobacter baylyi by Herrmann, Jennifer A, Koprowska, Agata, Winters, Tesa J, Villanueva, Nancy, Nikityuk, Victoria D, Pek, Feini, Reis, Elizabeth M, Dominguez, Constancia Z, Davis, Daniel, McPherson, Eric, Rocco, Staci R, Recendez, Cynthia, Difuntorum, Shyla M, Faeth, Kelly, Lopez, Mario D, Awwad, Habeeba M, Ghobashy, Rola A, Cappiello, Lauren, Neidle, Ellen L, Quiñones-Soto, Semarhy, Reams, Andrew B

“…Abstract The controversial theory of adaptive amplification states gene amplification mutations are induced by selective environments where they are enriched…”
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Distinct Effector-binding Sites Enable Synergistic Transcriptional Activation by BenM, a LysR-type Regulator by Ezezika, Obidimma C., Haddad, Sandra, Clark, Todd J., Neidle, Ellen L., Momany, Cory

“…BenM, a bacterial transcriptional regulator, responds synergistically to two effectors, benzoate and cis,cis-muconate. CatM, a paralog with overlapping…”
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Inducer responses of BenM, a LysR-type transcriptional regulator from Acinetobacter baylyi ADP1 by Craven, Sarah H, Ezezika, Obidimma C, Haddad, Sandra, Hall, Ruth A, Momany, Cory, Neidle, Ellen L

“…BenM and CatM control transcription of a complex regulon for aromatic compound degradation. These Acinetobacter baylyi paralogues belong to the largest family…”
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Versatility and Complexity: Common and Uncommon Facets of LysR-Type Transcriptional Regulators by Baugh, Alyssa C, Momany, Cory, Neidle, Ellen L

“…LysR-type transcriptional regulators (LTTRs) form one of the largest families of bacterial regulators. They are widely distributed and contribute to all…”
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Discovery of a Gene Involved in a Third Bacterial Protoporphyrinogen Oxidase Activity through Comparative Genomic Analysis and Functional Complementation by BOYNTON, Tye O, GERDES, Svetlana, CRAVEN, Sarah H, NEIDLE, Ellen L, PHILLIPS, John D, DAILEY, Harry A

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Selection for gene clustering by tandem duplication by REAMS, Andrew B, NEIDLE, Ellen L

“…In prokaryotic genomes, related genes are frequently clustered in operons and higher-order arrangements that reflect functional context. Organization emerges…”
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Analysis of IS1236-Mediated Gene Amplification Events in Acinetobacter baylyi ADP1 by Cuff, Laura E, Elliott, Kathryn T, Seaton, Sarah C, Ishaq, Maliha K, Laniohan, Nicole S, Karls, Anna C, Neidle, Ellen L

“…Recombination between insertion sequence copies can cause genetic deletion, inversion, or duplication. However, it is difficult to assess the fraction of all…”
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Genome plasticity in Acinetobacter: new degradative capabilities acquired by the spontaneous amplification of large chromosomal segments by Reams, Andrew B., Neidle, Ellen L.

“…Summary In Acinetobacter sp. ADP1, growth on benzoate requires regulation of the cat genes by two transcriptional activators. Here, mutants were obtained from…”
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Characterization of Highly Ferulate-Tolerant Acinetobacter baylyi ADP1 Isolates by a Rapid Reverse Engineering Method by Luo, Jin, McIntyre, Emily A, Bedore, Stacy R, Santala, Ville, Neidle, Ellen L, Santala, Suvi

“…Adaptive laboratory evolution (ALE) is a powerful approach for improving phenotypes of microbial hosts. Evolved strains typically contain numerous mutations…”
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Gene Amplification Involves Site-specific Short Homology-independent Illegitimate Recombination in Acinetobacter sp. Strain ADP1 by Reams, Andrew B, Neidle, Ellen L

“…A system for studying gene amplification in the bacterium Acinetobacter sp. strain ADP1 was used to isolate 105 spontaneous mutants. The method selects for the…”
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The DNA-binding domain of BenM reveals the structural basis for the recognition of a T-N11-A sequence motif by LysR-type transcriptional regulators by Alanazi, Amer M., Neidle, Ellen L., Momany, Cory

“…LysR‐type transcriptional regulators (LTTRs) play critical roles in metabolism and constitute the largest family of bacterial regulators. To understand…”
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Accelerating pathway evolution by increasing the gene dosage of chromosomal segments by Tumen-Velasquez, Melissa, Johnson, Christopher W., Ahmed, Alaa, Dominick, Graham, Fulk, Emily M., Khanna, Payal, Lee, Sarah A., Schmidt, Alicia L., Linger, Jeffrey G., Eiteman, Mark A., Beckham, Gregg T., Neidle, Ellen L.

“…Experimental evolution is a critical tool in many disciplines, including metabolic engineering and synthetic biology. However, current methods rely on the…”
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Gene amplification, laboratory evolution, and biosensor screening reveal MucK as a terephthalic acid transporter in Acinetobacter baylyi ADP1 by Pardo, Isabel, Jha, Ramesh K., Bermel, Ryan E., Bratti, Felicia, Gaddis, Molly, McIntyre, Emily, Michener, William, Neidle, Ellen L., Dale, Taraka, Beckham, Gregg T., Johnson, Christopher W.

“…Microbial terephthalic acid (TPA) catabolic pathways are conserved among the few bacteria known to turnover this xenobiotic aromatic compound. However, to date…”
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Development of a genetic toolset for the highly engineerable and metabolically versatile Acinetobacter baylyi ADP1 by Biggs, Bradley W, Bedore, Stacy R, Arvay, Erika, Huang, Shu, Subramanian, Harshith, McIntyre, Emily A, Duscent-Maitland, Chantel V, Neidle, Ellen L, Tyo, Keith E J

“…Abstract One primary objective of synthetic biology is to improve the sustainability of chemical manufacturing. Naturally occurring biological systems can…”
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Synergistic Transcriptional Activation by One Regulatory Protein in Response to Two Metabolites by Bundy, Becky M., Collier, Lauren S., Hoover, Timothy R., Neidle, Ellen L.

“…BenM is a LysR-type bacterial transcriptional regulator that controls aromatic compound degradation in Acinetobacter sp. ADP1. Here, in vitro transcription…”
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Diverse Organization of Genes of the β-Ketoadipate Pathway in Members of the Marine Roseobacter Lineage by BUCHAN, Alison, NEIDLE, Ellen L, MORAN, Mary Ann

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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