Search Results - "Neidhart, Jeffrey D"
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Tocilizumab in Patients Hospitalized with Covid-19 Pneumonia
Published in The New England journal of medicine (07-01-2021)“…In a randomized trial, the risk of mechanical ventilation or death among patients hospitalized with Covid-19 pneumonia (56.0% Hispanic or Latino, 14.9% Black,…”
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First-in-human phase 1/2a trial of CRLX101, a cyclodextrin-containing polymer-camptothecin nanopharmaceutical in patients with advanced solid tumor malignancies
Published in Investigational new drugs (01-08-2013)“…Summary Patients with advanced solid malignancies were enrolled to an open-label, single-arm, dose-escalation study, in which CRLX101 was administered…”
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Efficacy and Safety of Replacing Lenalidomide with Pomalidomide for Patients with Multiple Myeloma Refractory to a Lenalidomide-Containing Combination Regimen
Published in Experimental hematology (01-10-2022)“…•Pomalidomide is possibly a replacement drug for myeloma patients refractory to lenalidomide.•Pomalidomide achieves responses among myeloma patients refractory…”
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A randomized Phase II trial of the tumor vascular disrupting agent CA4P (fosbretabulin tromethamine) with carboplatin, paclitaxel, and bevacizumab in advanced nonsquamous non-small-cell lung cancer
Published in OncoTargets and therapy (2016)“…Combretastatin A4-phosphate, fosbretabulin tromethamine (CA4P) is a vascular disrupting agent that targets tumor vasculature. This study evaluated the safety…”
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Efficacy and safety of pomalidomide as a replacement therapy for lenalidomide for relapsed/refractory multiple myeloma patients refractory to a lenalidomide-containing combination regimen
Published in Journal of clinical oncology (20-05-2018)“…Abstract only…”
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Efficacy and Safety of Pomalidomide As a Replacement Therapy for Lenalidomide for Relapsed/Refractory Multiple Myeloma Patients Refractory to a Lenalidomide-Containing Combination Regimen
Published in Blood (08-12-2017)“…Introduction Pomalidomide (POM) is an immunomodulatory drug shown to be safe and effective for the treatment of relapsed/refractory multiple myeloma (RRMM)…”
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Obinutuzumab-Based Immunochemotherapy Prolongs Progression-Free Survival and Time to Next Anti-Lymphoma Treatment in Patients with Previously Untreated Follicular Lymphoma: Four-Year Results from the Phase III GALLIUM Study
Published in Blood (29-11-2018)“…Introduction: Immunochemotherapy is standard of care treatment for previously untreated patients (pts) with advanced stage follicular lymphoma (FL). However,…”
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Analysis of efficacy and safety of POM as a replacement therapy for lenalidomide for relapsed/refractory multiple myeloma pts refractory to a lenalidomide-containing combination regimen
Published in Journal of clinical oncology (20-05-2017)“…Abstract only e19528 Background: Pomalidomide (POM) is a third –generation immunomodulatory drug shown to be safe and effective for the treatment of…”
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B-F1RST: Assessment of novel blood-based biomarkers in patients with first-line advanced or metastatic NSCLC receiving atezolizumab monotherapy
Published in Journal of clinical oncology (20-05-2017)“…Abstract only TPS9103 Background: The anti–PD-L1 monoclonal antibody atezolizumab inhibits the interaction of PD-L1 with its receptors PD-1 and B7.1, thereby…”
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A randomized Phase II trial of the tumor vascular disrupting agent CA4P
Published in OncoTargets and therapy (02-01-2016)Get full text
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Abstract A97: Final phase 1/2a results evaluating the cyclodextrin-containing nanoparticle CRLX101 in patients with advanced solid tumor malignancies
Published in Molecular cancer therapeutics (12-11-2011)“…Introduction: Topoisomerase-1-inhibiting camptothecin (CPT) and derivatives such as irinotecan (CPT-11) and topotecan demonstrate clinical utility across…”
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