Search Results - "Nehlig, A"

Subtle alterations in memory systems and normal visual attention in the GAERS model of absence epilepsy by Marques-Carneiro, J.E, Faure, J.-B, Barbelivien, A, Nehlig, A, Cassel, J.-C

“…Highlights • We tested the functionality of memory systems and of sustained visual attention. • GAERS showed slower learning and weaker working memory in the…”
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Recurrent seizures and hippocampal sclerosis following intrahippocampal kainate injection in adult mice: electroencephalography, histopathology and synaptic reorganization similar to mesial temporal lobe epilepsy by Bouilleret, V, Ridoux, V, Depaulis, A, Marescaux, C, Nehlig, A, Le Gal La Salle, G

“…Human mesial temporal lobe epilepsy is characterized by hippocampal seizures associated with pyramidal cell loss in the hippocampus and dispersion of dentate…”
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Neuroprotective properties of topiramate in the lithium-pilocarpine model of epilepsy by Rigoulot, M A, Koning, E, Ferrandon, A, Nehlig, A

“…The lithium-pilocarpine model reproduces the main characteristics of human temporal lobe epilepsy. After status epilepticus (SE), rats exhibit a latent…”
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A 5‐Month Period of Epilepsy Impairs Spatial Memory, Decreases Anxiety, but Spares Object Recognition in the Lithium‐pilocarpine Model in Adult Rats by Detour, Julien, Schroeder, Henri, Desor, Didier, Nehlig, Astrid

“…Purpose: In temporal lobe epilepsy (TLE), interictal behavioral disorders affect patients' quality of life. Therefore we studied long‐term behavioral…”
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Temporal patterns of the cerebral inflammatory response in the rat lithium–pilocarpine model of temporal lobe epilepsy by Voutsinos-Porche, Brigitte, Koning, Estelle, Kaplan, Hervé, Ferrandon, Arielle, Guenounou, Moncef, Nehlig, Astrid, Motte, Jacques

“…To better understand the role of inflammatory responses in temporal lobe epilepsy, we characterized Interleukin1- β (IL1- β), Nuclear Factor- κB (NF- κB), and…”
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Ultra fast in vivo microwave irradiation for enhanced metabolic stability of brain biopsy samples during HRMAS NMR analysis by Detour, J., Elbayed, K., Piotto, M., Moussallieh, F.M., Nehlig, A., Namer, I.J.

“…► Using HRMAS NMR we studied effects of ultra fast in vivo microwave (MW) irradiation on brain samples. ► We confirmed limitation of post mortem metabolism. ►…”
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Intact neurobehavioral development and dramatic impairments of procedural-like memory following neonatal ventral hippocampal lesion in rats by Lecourtier, L, Antal, M.-C, Cosquer, B, Schumacher, A, Samama, B, Angst, M.-J, Ferrandon, A, Koning, E, Cassel, J.-C, Nehlig, A

“…Abstract Neonatal ventral hippocampal lesions (NVHL) in rats are considered a potent developmental model of schizophrenia. After NVHL, rats appear normal…”
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Prolonged refractory status epilepticus with early and persistent restricted hippocampal signal MRI abnormality by Chevret, L., Husson, B., Nguefack, S., Nehlig, A., Bouilleret, V.

“…We report a series of four children with a prolonged refractory status epilepticus with an early persistent and restricted hippocampal signal MRI abnormality…”
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SPM analysis of ictal–interictal SPECT in mesial temporal lobe epilepsy: Relationships between ictal semiology and perfusion changes by Chassagnon, S, Namer, I.J, Armspach, J.P, Nehlig, A, Kahane, P, Kehrli, P, Valenti, M.P, Hirsch, E

“…Summary A combination of temporo-limbic hyperperfusion and extratemporal hypoperfusion was observed during complex partial seizures (CPS) in temporal lobe…”
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The lesional and epileptogenic consequences of lithium–pilocarpine-induced status epilepticus are affected by previous exposure to isolated seizures: effects of amygdala kindling and maximal electroshocks by André, V, Ferrandon, A, Marescaux, C, Nehlig, A

“…In temporal lobe epilepsy, the occurrence of seizures seems to correlate with the presence of lesions underlying the establishment of a hyperexcitable circuit…”
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The amygdala is critical for seizure propagation from brainstem to forebrain by Hirsch, E, Danober, L, Simler, S, Pereira de Vasconcelos, A, Maton, B, Nehlig, A, Marescaux, C, Vergnes, M

“…Audiogenic seizures, a model of brainstem epilepsy, are characterized by a tonic phase (sustained muscular contraction fixing the limbs in a flexed or extended…”
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Caffeine and sports activity: a review by Nehlig, A, Debry, G

“…Potential ergogenic effects of caffeine at the cellular level are mediated by three main mechanisms of action which are: intracellular mobilization of calcium…”
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Are we dependent upon coffee and caffeine? A review on human and animal data by Nehlig, Astrid

“…Caffeine is the most widely used psychoactive substance and has been considered occasionally as a drug of abuse. The present paper reviews available data on…”
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The model of pentylenetetrazol-induced status epilepticus in the immature rat: short- and long-term effects by Nehlig, Astrid, de Vasconcelos, Anne Pereira

“…In order to assess acute, short and long-term effects of seizures in the immature rat brain, we studied the metabolic, circulatory and histopathological…”
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Hypervascularization in the Magnocellular Nuclei of the Rat Hypothalamus: Relationship with the Distribution of Aquaporin-4 and Markers of Energy Metabolism by Badaut, J., Nehlig, A., Verbavatz, J.-M., Stoeckel, M.-E., Freund-Mercier, M.-J., Lasbennes, F.

“…In the magnocellular nuclei of the hypothalamus, there is a rich vascular network for which the function remains to be established. In the supraoptic nucleus,…”
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Modifications of local cerebral glucose utilization in thalamic structures following injection of a dopaminergic agonist in the nucleus accumbens—involvement in antiepileptic effects? by Riban, V., Pereira de Vasconcelos, A., Phâm-Lê, B.T., Ferrandon, A., Marescaux, C., Nehlig, A., Depaulis, A.

“…Dopaminergic transmission in the nucleus accumbens (NAcc) is implicated in different aspects of reward and motivational mechanisms. More recently, it has been…”
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Epileptogenic and non-epileptogenic zones: blood flow studies of temporo-limbic seizures by Chassagnon, S, Armspach, J P, Namer, I J, Kehrli, P, Hirsch, E, Nehlig, A

“…To assess the contribution of ictal SPECT to the definition of the epileptogenic zone (EZ) prior to surgery in focal drug-resistant epilepsies, we investigated…”
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Vigabatrin, the gaba-transaminase inhibitor, damages cone photoreceptors in rats by Duboc, A., Hanoteau, N., Simonutti, M., Rudolf, G., Nehlig, A., Sahel, J.A., Picaud, S.

“…In epilepsy, enhancing GABAinhibitory neurotransmission has become a major therapeutic strategy to limit the occurrence of seizures. Vigabatrin (which blocks…”
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Brain uptake and metabolism of ketone bodies in animal models by Nehlig, Astrid

“…As a consequence of the high fat content of maternal milk, the brain metabolism of the suckling rat represents a model of naturally occurring ketosis. During…”
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Absence seizures induce a decrease in cerebral blood flow: human and animal data by Nehlig, A, Vergnes, M, Waydelich, R, Hirsch, E, Charbonne, R, Marescaux, C, Seylaz, J

“…Our previous studies on cerebral metabolic activity in genetic absence epilepsy rats from Strasbourg (GAERS) were in favor of decreased functional activity…”
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