Search Results - "Nehilla, Barrett J."

Human Immunodeficiency Virus (HIV) Separation and Enrichment via the Combination of Antiviral Lectin Recognition and a Thermoresponsive Reagent System by Phan, Joseph C., Nehilla, Barrett J., Srinivasan, Selvi, Coombs, Robert W., Woodrow, Kim A., Lai, James J.

“…Purpose In order to improve the detection limit of existing HIV diagnostic assays, we explored the use of a temperature-responsive magnetic nanoparticle…”
Get full text

Peptide-Conjugated Quantum Dots Activate Neuronal Receptors and Initiate Downstream Signaling of Neurite Growth by Vu, Tania Q, Maddipati, Ravikanth, Blute, Todd A, Nehilla, Barrett J, Nusblat, Leora, Desai, Tejal A

“…Quantum dots (QDs) could serve as fluorescent scaffolds for effecting specific physiological and pharmacological responses in cells. Here, we conjugate the…”
Get full text

A Stimuli-Responsive, Binary Reagent System for Rapid Isolation of Protein Biomarkers by Nehilla, Barrett J, Hill, John J, Srinivasan, Selvi, Chen, Yen-Chi, Schulte, Thomas H, Stayton, Patrick S, Lai, James J

“…Magnetic microbeads exhibit rapid separation characteristics and are widely employed for biomolecule and cell isolations in research laboratories, clinical…”
Get full text

Surfactant-Free, Drug-Quantum-Dot Coloaded Poly(lactide-co-glycolide) Nanoparticles: Towards Multifunctional Nanoparticles by Nehilla, Barrett J, Allen, Philip G, Desai, Tejal A

“…Nanoprecipitation was utilized to synthesize biodegradable and surfactant-free nanoparticles loaded with quantum dots. This protocol also yielded nanoparticles…”
Get full text

Finite element modeling to analyze TEER values across silicon nanomembranes by Khire, Tejas S., Nehilla, Barrett J., Getpreecharsawas, Jirachai, Gracheva, Maria E., Waugh, Richard E., McGrath, James L.

“…Silicon nanomembranes are ultrathin, highly permeable, optically transparent and biocompatible substrates for the construction of barrier tissue models…”
Get full text

Stimuli-Responsive Polymer-Antibody Conjugates via RAFT and Tetrafluorophenyl Active Ester Chemistry by Roy, Debashish, Nehilla, Barrett J, Lai, James J, Stayton, Patrick S

“…Highly efficient polymer-antibody conjugations were demonstrated via a tetrafluorophenyl active ester. A well-defined diblock copolymer was synthesized by…”
Get full text

Endothelial vacuolization induced by highly permeable silicon membranes by Nehilla, Barrett J., Nataraj, Nakul, Gaborski, Thomas R., McGrath, James L.

“…Assays for initiating, controlling and studying endothelial cell behavior and blood vessel formation have applications in developmental biology, cancer and…”
Get full text

Purified and surfactant-free coenzyme Q10-loaded biodegradable nanoparticles by Nehilla, Barrett J., Bergkvist, Magnus, Popat, Ketul C., Desai, Tejal A.

“…The intent of this work was to synthesize and comprehensively characterize ubiquinone-loaded, surfactant-free biodegradable poly(lactic- co-glycolic acid)…”
Get full text

Finite element modeling to analyze TEER values across silicon nanomembranes by Khire, Tejas S., Nehilla, Barrett J., Getpreecharsawas, Jirachai, Gracheva, Maria E., Waugh, Richard E., McGrath, James L.

Get full text

Stoichiometry-Dependent Formation of Quantum Dot−Antibody Bioconjugates:  A Complementary Atomic Force Microscopy and Agarose Gel Electrophoresis Study by Nehilla, Barrett J, Vu, Tania Q, Desai, Tejal A

“…The unique advantages of quantum dot (QD) bioconjugates have motivated their application in biological assays. However, physical characterization of…”
Get full text

Neurotransmitter analog tethered to a silicon platform for neuro-bioMEMS applications by Nehilla, Barrett J., Popat, Ketul C., Vu, Tania Q., Chowdhury, Sarwat, Standaert, Robert F., Pepperberg, David R., Desai, Tejal A.

“…The design of chemically well‐defined, machinable surfaces containing neuroactive molecules offers potential for fundamental neuroscience and clinical neural…”
Get full text

Abstract 232: An antibody-drug conjugate carrying a microtubule inhibitor and a DNA alkylator exerts both mechanisms of action on tumor cells by Duvall, Jeremy R., Damelin, Marc, Kozytska, Mariya V., Nehilla, Barrett J., Protopopova, Marina, Conlon, Patrick R., Qin, LiuLiang, Nazzaro, Mark, Thomas, Josh D., Zhang, Qingxiu, Toader, Dorin, Lowinger, Timothy B.

“…Antibody-drug conjugates (ADCs) consist of a tumor-targeted antibody, a drug (payload) with specified mechanism of action, and the chemical framework for…”
Get full text

Abstract 2687: Dolasynthen–a novel, homogeneous Auristatin F hydroxypropyl amide antibody-drug conjugate platform by Toader, Dorin, Damelin, Marc, Dirksen, Anouk, Fesler, Shawn P., Collins, Scott D., Nehilla, Barrett J., Xu, Jian, Xu, Ling, Cattcott, Kalli C., Uttard, Alex, Lee, Winnie, Clardy, Susan, Stevenson, Cheri A., Qin, LiuLiang, Conlon, Patrick R., Kozytska, Mariya V., Chin, Chen-Ni, Lee, David H., Lowinger, Timothy B.

“…Dolasynthen is a novel, fully synthetic, structurally homogeneous platform that enables the construction of ADCs with tunable drug-to-antibody ratios (DAR),…”
Get full text

Highly permeable membranes for live cell imaging of co‐cultures by Gaborski, Thomas R, Nehilla, Barrett J, Striemer, Christopher C, McGrath, James L

“…A new class of porous membrane, porous nanocrystalline silicon (pnc‐Si) has been fabricated that is unique in its combination of nanoscale thickness (5–30 nm)…”
Get full text

Ligand-conjugated quantum dots for targeted drug delivery to nerve cells by Vu, T.Q., Maddipati, R., Blute, T.A., Nehilla, B.J., Nusblat, L., Desai, T.A.

“…Increased interest in nanoparticle quantum dots as fluorescent probes possessing extended photostability, multi-color capability, and surface-controllable…”
Get full text