Search Results - "Negron, Vivian"
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Pleistocene aridification underlies the evolutionary history of the Caribbean endemic, insular, giant Consolea (Opuntioideae)
Published in American journal of botany (01-02-2021)“…Premise The Caribbean islands are in the top five biodiversity hotspots on the planet; however, the biogeographic history of the seasonally dry tropical forest…”
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DnaJ Heat Shock Protein Family B Member 9 Is a Novel Biomarker for Fibrillary GN
Published in Journal of the American Society of Nephrology (01-01-2018)“…Fibrillary GN (FGN) is a rare primary glomerular disease. Histologic and histochemical features of FGN overlap with those of other glomerular diseases, and no…”
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3
Impact of histopathology, tumor-infiltrating lymphocytes, and adjuvant chemotherapy on prognosis of triple-negative breast cancer
Published in Breast cancer research and treatment (01-01-2018)“…Background Given its high recurrence risk, guidelines recommend systemic therapy for most patients with early-stage triple-negative breast cancer (TNBC). While…”
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Optimized immunohistochemical detection of estrogen receptor beta using two validated monoclonal antibodies confirms its expression in normal and malignant breast tissues
Published in Breast cancer research and treatment (01-01-2020)“…Purpose Significant controversy exists regarding the expression patterns of estrogen receptor beta (ERβ) in normal and diseased breast tissue. To address this…”
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Centrosome Amplification Drives Chromosomal Instability in Breast Tumor Development
Published in Proceedings of the National Academy of Sciences - PNAS (19-02-2002)“…Earlier studies of invasive breast tumors have shown that 60-80% are aneuploid and ≈80% exhibit amplified centrosomes. In this study, we investigated the…”
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Control of centrin stability by Aurora A
Published in PloS one (23-06-2011)“…Aurora A is an oncogenic serine/threonine kinase which can cause cell transformation and centrosome amplification when over-expressed. Human breast tumors show…”
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Pazopanib enhances paclitaxel-induced mitotic catastrophe in anaplastic thyroid cancer
Published in Science translational medicine (02-01-2013)“…Anaplastic thyroid cancer (ATC) has perhaps the worst prognosis of any cancer, with a median survival of only about 5 months regardless of stage. Pazopanib…”
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Short Term Cyclin D1 Overexpression Induces Centrosome Amplification, Mitotic Spindle Abnormalities, and Aneuploidy
Published in The Journal of biological chemistry (07-01-2005)“…In normal cells, cyclin D1 is induced by growth factors and promotes progression through the G1 phase of the cell cycle. Cyclin D1 is also an oncogene that is…”
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Chronic exposure to lead chromate causes centrosome abnormalities and aneuploidy in human lung cells
Published in Cancer research (Chicago, Ill.) (15-04-2006)“…Hexavalent chromium [Cr(VI)] compounds are established human lung carcinogens. The carcinogenicity of Cr(VI) is related to its solubility, with the most potent…”
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A promising approach for treatment of tumor-induced bone diseases: Utilizing bisphosphonate derivatives of nucleoside antimetabolites
Published in Bone (New York, N.Y.) (01-07-2010)“…Abstract Despite palliative treatments, tumor-induced bone disease (TIBD) remains highly debilitating for many cancer patients and progression typically…”
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Aurora a and B overexpression and centrosome amplification in early estrogen-induced tumor foci in the Syrian hamster kidney: implications for chromosomal instability, aneuploidy, and neoplasia
Published in Cancer research (Chicago, Ill.) (01-04-2007)“…Estrogen-induced Syrian hamster tumors in the kidney represent a useful model to gain insight into the role of estrogens in oncogenic processes. We provided…”
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Amplified centrosomes in breast cancer: a potential indicator of tumor aggressiveness
Published in Breast cancer research and treatment (01-09-2002)“…Molecular mechanisms leading to genomic instability and phenotypic variation during tumor development and progression are poorly understood. Such instability…”
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Heterochrony and its role in sex determination of cryptically dioecious Consolea (Cactaceae) staminate flowers
Published in Botanical journal of the Linnean Society (01-02-2008)“…Ovule development, megasporogenesis, and megagametogenesis were studied in six cryptically dioecious species of Consolea. All species showed uniform…”
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Genetic Variation among Rare Florida Endemic Hymenocallis henryae Populations and the Implication for Conservation and Management
Published in Diversity (Basel) (01-08-2024)“…Hymenocallis henryae is a rare, charismatic spider lily endemic to the Florida panhandle. Currently under review to determine if listing under the Endangered…”
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Chromosome numbers, nuclear DNA content, and polyploidy in Consolea (Cactaceae), an endemic cactus of the Caribbean Islands
Published in American journal of botany (01-08-2007)“…Polyploidy, an important mechanism of plant evolution, was investigated in Consolea, an endemic Caribbean opuntioid genus represented by nine subdioecious…”
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Protocadherin 7-Associated Membranous Nephropathy
Published in Journal of the American Society of Nephrology (01-05-2021)“…Membranous nephropathy (MN) results from deposition of antigen-antibody complexes along the glomerular basement membrane (GBM). PLA2R, THSD7A, NELL1, and…”
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High Prevalence of Clonal Reproduction and Low Genetic Diversity in Scutellaria floridana , a Federally Threatened Florida-Endemic Mint
Published in Plants (Basel) (17-02-2023)“…The threatened mint Florida skullcap ( ) is endemic to four counties in the Florida panhandle. Because development and habitat modification extirpated several…”
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Hematopoietic Stem Cell Transplant-Membranous Nephropathy Is Associated with Protocadherin FAT1
Published in Journal of the American Society of Nephrology (01-05-2022)“…Membranous nephropathy (MN) is a common cause of proteinuria in patients receiving a hematopoietic stem cell transplant (HSCT). The target antigen in…”
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Novel Target Antigens in Sarcoidosis-Associated Membranous Nephropathy: FR-PO671
Published in Journal of the American Society of Nephrology (01-11-2022)Get full text
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In Patients with Membranous Lupus Nephritis, Exostosin-Positivity and Exostosin-Negativity Represent Two Different Phenotypes
Published in Journal of the American Society of Nephrology (01-03-2021)“…In patients with secondary (autoimmune) membranous nephropathy, two novel proteins, Exostosin 1 and Exostosin 2 (EXT1/EXT2), are potential disease antigens,…”
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