Search Results - "Negrelli, Karina"

Plasma ceramides as biomarkers for microvascular disease and clinical outcomes in diabetes and myocardial infarction by Junqueira, Debora Leonor, Cavalcanti, Alexandre Biasi, Sallum, Juliana Maria Ferraz, Yasaki, Erika, de Andrade Jesuíno, Isabella, Stach, Alline, Negrelli, Karina, de Oliveira Silva, Leila, Lopes, Marcela Almeida, Caixeta, Adriano, Chan, Mark Yy, Ching, Jianhong, Carvalho, Valdemir Malechco, Faccio, Andrea Tedesco, Tsutsui, Jeane, Rizzatti, Edgar, Fonseca, Rafael Almeida, Summers, Scott, Fonseca, Henrique Almeida, Rochitte, Carlos Eduardo, Krieger, José Eduardo, de Carvalho, Leonardo Pinto

“…Ceramides have recently been identified as novel biomarkers associated with diabetes mellitus (DM) and major adverse cardiac and cerebrovascular events…”
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Halofuginone for non-hospitalized adult patients with COVID-19 a multicenter, randomized placebo-controlled phase 2 trial. The HALOS trial by Tomazini, Bruno Martins, Tramujas, Lucas, Medrado, Junior, Fernando Azevedo, Gomes, Samara Pinheiro do Carmo, Negrelli, Karina Leal, Murinize, Gabriela Souza, Santos, Renato Hideo Nakagawa, Vianna, Bruna Martins Pereira, Piotto, Bruna Fornazieri, Veiga, Thabata Silva, Santos, Bianca Rodrigues do, Peneluppi Horak, Ana Clara, Lemos, Olivia Mora Cavalcante, Lopes, Marcela de Almeida, Olicheski, Beatriz Baptista, Campones, Diego Lurentt, Peixoto, Luiz Angelo Alencar, Basilio, Aline Dos Anjos Chaves, Gebara, Otavio Celso Eluf, Lopes, Ana Tarina Alvarez, Saconato, Humberto, Valeis, Nanci, Miranda, Tamiris Abait, Laranjeira, Ligia Nasi, Santucci, Eliana Vieira, Carlin, Aaron Foster, Esko, Jeffrey David, Gordts, Phillip Leo Stephan Marie, Tsimikas, Sotirios, Cavalcanti, Alexandre Biasi

“…Halofuginone (PJS-539) is an oral prolyl-tRNA synthetase inhibitor that has a potent in vitro activity against SARS-CoV-2 virus. The safety and efficacy of…”
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Antisense therapy to block the Kallikrein-kinin pathway in COVID-19: The ASKCOV randomized controlled trial by Zampieri, Fernando G., Westphal, Glauco Adrieno, Santos, Maria Adelaide Dos, Gomes, Samara P.C., Gomes, Jackeline O., Negrelli, Karina L., Santos, Renato H.N., Ishihara, Luciana M., Miranda, Tamiris A., Laranjeira, Ligia N., Valeis, Nanci, Santucci, Eliana Vieira, de Souza Dantas, Vicente Cés, Gebara, Otávio, Cohn, Danny M., Buchele, Gustavo, Janiszewski, Mariano, de Freitas, Flávio Geraldo, Dal-Pizzol, Felipe, de Matos Soeiro, Alexandre, Berti, Isabele Ribeiro, Germano, Almir, Schettini, Daniel Almeida, Rosa, Regis G., Falavigna, Maicon, Veiga, Viviane C., Azevedo, Luciano C.P., Damiani, Lucas P., Machado, Flávia R., Cavalcanti, Alexandre B.

“…To assess the effect of antisense therapy to block kallikrein-kinin pathway in COVID-19 patients. Randomized, placebo-controlled, double blind, controlled…”
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High flow nasal catheter therapy versus non-invasive positive pressure ventilation in acute respiratory failure (RENOVATE trial): protocol and statistical analysis plan by Maia, Israel S., Kawano-Dourado, Leticia, Zampieri, Fernando G., Damiani, Lucas P., Nakagawa, Renato H., Gurgel, Rodrigo M., Negrelli, Karina, Gomes, Samara P.C., Paisani, Denise, Lima, Lucas M., Santucci, Eliana V., Valeis, Nanci, Laranjeira, Ligia N., Lewis, Roger, Fitzgerald, Mark, Carvalho, Carlos R.R., Brochard, Laurent, Cavalcanti, Alexandre B.

“…Background: The best way to offer non-invasive respiratory support across several aetiologies of acute respiratory failure (ARF) is presently unclear. Both…”
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Automated documentation of vital parameters in wards using portable stations - Effect on proper triggering of the rapid response team: a study protocol of a cluster randomized clinical trial by Ribeiro, José Cesar, Sgorbissa, Cristina, Silva, Karla Aparecida, Braz, Maria de Lourdes Dias, Horak, Ana Clara Peneluppi, Nicola, Marina Lazzari, Gurgel, Rodrigo Magalhães, Tokunaga, Samira Martins, Negrelli, Karina Leal, Murizine, Gabriela Souza, Medrado Júnior, Fernando, Coli, Rita de Cassia Pires, Cavalcanti, Alexandre Biasi, Marcadenti, Aline

“…To evaluate the effectiveness of the Welch Allyn Connex® Spot Monitor/Hillrom Connecta™ solution in activating the rapid response team in a timely manner…”
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An adapted cardioprotective diet with or without phytosterol and/or krill oil supplement in familial hypercholesterolemia: A pilot study protocol by de Abreu-Silva, Erlon Oliveira, Machado, Rachel Helena Vieira, dos Santos, Bianca Rodrigues, Kojima, Flávia Soares, Santos, Renato Hideo Nakagawa, Murizine, Gabriela Souza, Homsi, Jordana Rosa, Negrelli, Karina Leal, Barbante, Letícia Galvão, de Barros e Silva, Pedro G.M., de Lima, Andressa Gusmão, Tramujas, Lucas, Bersch-Ferreira, Ângela Cristine, Carvalho, Adriana Bastos, de Oliveira, Thaís Martins, Izar, Maria Cristina, Sampaio, Geni Rodrigues, Damasceno, Nágila Raquel Teixeira, Rogero, Marcelo Macedo, da Silva Torres, Elizabeth Aparecida Ferraz, Costa, Rosana Perim, de Souza Mota, Luís Gustavo, Krey, Julia Pinheiro, da Silva, Lucas Ribeiro, de Luca, Patrícia Vieira, Amaral, Cristiane Kovacs, de Oliveira, Patricia Rodrigues, da Silva, Renata Alves, Moreira, Priscila, dos Santos, Elisa Maia, de Melo, Rodrigo Morel Vieira, Lima, Eduardo Gomes, de Luca, André, Heck, Thiago Gomes, Carvalho, Ana Paula Perillo Ferreira, Garofallo, Silvia Bueno, Cavalcanti, Alexandre Biasi, Marcadenti, Aline

“…A healthy diet is one of the pillars of familial hypercholesterolemia (FH) treatment. However, the best dietary pattern and indication for specific…”
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Antivirals for adult patients hospitalised with SARS-CoV-2 infection: a randomised, phase II/III, multicentre, placebo-controlled, adaptive study, with multiple arms and stages. COALITION COVID-19 BRAZIL IX – REVOLUTIOn trial by Maia, Israel S., Marcadenti, Aline, Veiga, Viviane C., Miranda, Tamiris A., Gomes, Samara P.C., Carollo, Mariana B.S., Negrelli, Karina L., Gomes, Jackeline O., Tramujas, Lucas, Abreu-Silva, Erlon O., Westphal, Glauco A., Fernandes, Ruthy P., Horta, Jacques G.A., Oliveira, Deborah C., Flato, Uri A.P., Paoliello, Ricardo C.R., Fernandes, Camilo, Zandonai, Cássio L., Coelho, Juliana C., Barros, Waldemar C., Lemos, Juliana C., Bolan, Renata S., Dutra, Marcela M., Gebara, Otavio C.E., Lopes, Ana T.A., Alencar Filho, Meton S., Arraes, Jussara A., Hamamoto, Victor A., Hernandes, Mauro E., Golin, Nicole A., Santos, Tiago M., Santos, Renato H.N., Damiani, Lucas P., Zampieri, Fernando G., Gesto, João, Machado, Flávia R., Rosa, Régis G., Azevedo, Luciano C.P., Avezum, Alvaro, Lopes, Renato D., Souza, Thiago M.L., Berwanger, Otávio, Cavalcanti, Alexandre B.

“…Repurposed drugs for treatment of new onset disease may be an effective therapeutic shortcut. We aimed to evaluate the efficacy of repurposed antivirals…”
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Antivirals for adult patients hospitalized with SARS-CoV-2 infection: A randomized, Phase II/III, multicenter, placebo-controlled, adaptive study, with multiple arms and stages. COALITION COVID-19 BRAZIL IX - REVOLUTIOn: protocol and statistical analysis plan by Maia, Israel Silva, Marcadenti, Aline, Zampieri, Fernando Godinho, Damiani, Lucas Petri, Santos, Renato Hideo Nakagawa, Negrelli, Karina Leal, Gomes, Samara Pinheiro do Carmo, Gomes, Jaqueline Oliveira, Carollo, Mariana Barbosa dos Santos, Miranda, Tamiris Abait, Santucci, Eliana, Valeis, Nanci, Laranjeira, Ligia Nasi, Westphal, Glauco Adrieno, Horta, Jacques Gabriel Alvares, Flato, Uri Adrian Prync, Fernandes, Camilo, Barros, Waldemar Carlos, Bolan, Renata S, Gebara, Otávio Celso Eluf, Alencar Filho, Meton Soares de, Hamamoto, Victor Augusto, Hernandes, Mauro Esteves, Golin, Nicole Alberti, Olinda, Ronald Torres de, Machado, Flávia Ribeiro, Rosa, Régis Goulart, Veiga, Viviane Cordeiro, Azevedo, Luciano César Pontes de, Avezum, Alvaro, Lopes, Renato Delascio, Souza, Tiago Moreno L, Berwanger, Otávio, Cavalcanti, Alexandre Biasi, BRICNet, Coalition IX Investigators and the

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Antivirals for adult patients hospitalized with SARS-CoV-2 infection: A randomized, Phase II/III, multicenter, placebo-controlled, adaptive study, with multiple arms and stages. COALITION COVID-19 BRAZIL IX - REVOLUTIOn: protocol and statistical analysis plan by Maia, Israel Silva, Marcadenti, Aline, Zampieri, Fernando Godinho, Damiani, Lucas Petri, Santos, Renato Hideo Nakagawa, Negrelli, Karina Leal, Gomes, Samara Pinheiro do Carmo, Gomes, Jaqueline Oliveira, Carollo, Mariana Barbosa Dos Santos, Miranda, Tamiris Abait, Santucci, Eliana, Valeis, Nanci, Laranjeira, Ligia Nasi, Westphal, Glauco Adrieno, Horta, Jacques Gabriel Alvares, Flato, Uri Adrian Prync, Fernandes, Camilo, Barros, Waldemar Carlos, Bolan, Renata S, Gebara, Otávio Celso Eluf, Alencar Filho, Meton Soares de, Hamamoto, Victor Augusto, Hernandes, Mauro Esteves, Golin, Nicole Alberti, Olinda, Ronald Torres de, Machado, Flávia Ribeiro, Rosa, Régis Goulart, Veiga, Viviane Cordeiro, Azevedo, Luciano César Pontes de, Avezum, Alvaro, Lopes, Renato Delascio, Souza, Tiago Moreno L, Berwanger, Otávio, Cavalcanti, Alexandre Biasi

“…Repurposed drugs are important in resource-limited settings because the interventions are more rapidly available, have already been tested safely in other…”
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Documentação automatizada de parâmetros vitais em enfermarias utilizando estações portáteis - Efeito no acionamento adequado do time de resposta rápida: um protocolo de um ensaio clínico randomizado em clusters by Ribeiro, José Cesar, Sgorbissa, Cristina, Silva, Karla Aparecida, Braz, Maria de Lourdes Dias, Horak, Ana Clara Peneluppi, Nicola, Marina Lazzari, Gurgel, Rodrigo Magalhães, Tokunaga, Samira Martins, Negrelli, Karina Leal, Murizine, Gabriela Souza, Medrado Júnior, Fernando, Coli, Rita de Cassia Pires, Cavalcanti, Alexandre Biasi, Marcadenti, Aline

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Antivirais para pacientes adultos hospitalizados com infecção por SARS-CoV-2: Um estudo de Fase II/III, randomizado, multicêntrico, controlado por placebo, adaptativo, commúltiplosbraçoseestágios. COALITION COVID-19 BRAZIL IX – REVOLUTIOn: protocolo e plano de análise estatística by Maia, Israel Silva, Marcadenti, Aline, Zampieri, Fernando Godinho, Damiani, Lucas Petri, Santos, Renato Hideo Nakagawa, Negrelli, Karina Leal, Gomes, Samara Pinheiro do Carmo, Gomes, Jaqueline Oliveira, Carollo, Mariana Barbosa dos Santos, Miranda, Tamiris Abait, Santucci, Eliana, Valeis, Nanci, Laranjeira, Ligia Nasi, Westphal, Glauco Adrieno, Horta, Jacques Gabriel Alvares, Flato, Uri Adrian Prync, Fernandes, Camilo, Barros, Waldemar Carlos, Bolan, Renata S, Gebara, Otávio Celso Eluf, Alencar Filho, Meton Soares de, Hamamoto, Victor Augusto, Hernandes, Mauro Esteves, Golin, Nicole Alberti, Olinda, Ronald Torres de, Machado, Flávia Ribeiro, Rosa, Régis Goulart, Veiga, Viviane Cordeiro, Azevedo, Luciano César Pontes de, Avezum, Alvaro, Lopes, Renato Delascio, Souza, Tiago Moreno L, Berwanger, Otávio, Cavalcanti, Alexandre Biasi, BRICNet, Coalition IX Investigators and the

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Daily Chlorhexidine Bath for Health Care Associated Infection Prevention (CLEAN-IT): protocol for a multicenter cluster randomized crossover open-label trial by Tomazini, Bruno Martins, Veiga, Thabata Silva, Santos, Renato Hideo Nakagawa, Campos, Viviane Bezerra, Tokunaga, Samira Martins, Santos, Elton Sousa, Barbante, Leticia Galvão, Maia, Renato da Costa, Negrelli, Karina Leal, Valeis, Nanci, Santucci, Eliana Vieira, Laranjeira, Ligia Nasi, Medrado, Jr, Fernando Azevedo, Lisboa, Thiago Costa, Besen, Bruno Adler Maccagnan Pinheiro, Nassar Junior, Antônio Paulo, Veiga, Viviane Cordeiro, Pereira, Adriano José, Cavalcanti, Alexandre Biasi

“…Critically ill patients are at increased risk of health care-associated infections due to various devices (central line-associated bloodstream infection,…”
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Prospective, randomized, controlled trial assessing the effects of a driving pressure-limiting strategy for patients with acute respiratory distress syndrome due to community-acquired pneumonia (STAMINA trial): protocol and statistical analysis plan by Maia, Israel Silva, Medrado, Jr, Fernando Azevedo, Tramujas, Lucas, Tomazini, Bruno Martins, Oliveira, Júlia Souza, Sady, Erica Regina Ribeiro, Barbante, Letícia Galvão, Nicola, Marina Lazzari, Gurgel, Rodrigo Magalhães, Damiani, Lucas Petri, Negrelli, Karina Leal, Miranda, Tamiris Abait, Santucci, Eliana, Valeis, Nanci, Laranjeira, Ligia Nasi, Westphal, Glauco Adrieno, Fernandes, Ruthy Perotto, Zandonai, Cássio Luis, Pincelli, Mariangela Pimentel, Figueiredo, Rodrigo Cruvinel, Bustamante, Cíntia Loss Sartori, Norbin, Luiz Fernando, Boschi, Emerson, Lessa, Rafael, Romano, Marcelo Pereira, Miura, Mieko Cláudia, Alencar Filho, Meton Soares de, Dantas, Vicente Cés de Souza, Barreto, Priscilla Alves, Hernandes, Mauro Esteves, Grion, Cintia Magalhães Carvalho, Laranjeira, Alexandre Sanches, Mezzaroba, Ana Luiza, Bahl, Marina, Starke, Ana Carolina, Biondi, Rodrigo Santos, Dal-Pizzol, Felipe, Caser, Eliana Bernadete, Thompson, Marlus Muri, Padial, Andrea Allegrini, Veiga, Viviane Cordeiro, Leite, Rodrigo Thot, Araújo, Gustavo, Guimarães, Mário, Martins, Priscilla de Aquino, Lacerda, Fábio Holanda, Hoffmann Filho, Conrado Roberto, Melro, Livia, Pacheco, Eduardo, Ospina-Táscon, Gustavo Adolfo, Ferreira, Juliana Carvalho, Freires, Fabricio Jocundo Calado, Machado, Flávia Ribeiro, Cavalcanti, Alexandre Biasi, Zampieri, Fernando Godinho

“…Driving pressure has been suggested to be the main driver of ventilator-induced lung injury and mortality in observational studies of acute respiratory…”
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Antivirals for adult patients hospitalised with SARS-CoV-2 infection: a randomised, phase II/III, multicentre, placebo-controlled, adaptive study, with multiple arms and stages. COALITION COVID-19 BRAZIL IX – REVOLUTIOn trialResearch in context by Israel S. Maia, Aline Marcadenti, Viviane C. Veiga, Tamiris A. Miranda, Samara P.C. Gomes, Mariana B.S. Carollo, Karina L. Negrelli, Jackeline O. Gomes, Lucas Tramujas, Erlon O. Abreu-Silva, Glauco A. Westphal, Ruthy P. Fernandes, Jacques G.A. Horta, Deborah C. Oliveira, Uri A.P. Flato, Ricardo C.R. Paoliello, Camilo Fernandes, Cássio L. Zandonai, Juliana C. Coelho, Waldemar C. Barros, Juliana C. Lemos, Renata S. Bolan, Marcela M. Dutra, Otavio C.E. Gebara, Ana T.A. Lopes, Meton S. Alencar Filho, Jussara A. Arraes, Victor A. Hamamoto, Mauro E. Hernandes, Nicole A. Golin, Tiago M. Santos, Renato H.N. Santos, Lucas P. Damiani, Fernando G. Zampieri, João Gesto, Flávia R. Machado, Régis G. Rosa, Luciano C.P. Azevedo, Alvaro Avezum, Renato D. Lopes, Thiago M.L. Souza, Otávio Berwanger, Alexandre B. Cavalcanti

“…Background: Repurposed drugs for treatment of new onset disease may be an effective therapeutic shortcut. We aimed to evaluate the efficacy of repurposed…”
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Daily Chlorhexidine Bath for Health Care Associated Infection Prevention (CLEAN-IT): protocolo de um estudo multicêntrico, aberto, randomizado, em cluster com cruzamentos by Tomazini, Bruno Martins, Veiga, Thabata Silva, Santos, Renato Hideo Nakagawa, Campos, Viviane Bezerra, Tokunaga, Samira Martins, Santos, Elton Sousa, Barbante, Leticia Galvão, Maia, Renato da Costa, Negrelli, Karina Leal, Valeis, Nanci, Santucci, Eliana Vieira, Laranjeira, Ligia Nasi, Medrado Jr, Fernando Azevedo, Lisboa, Thiago Costa, Besen, Bruno Adler Maccagnan Pinheiro, Nassar Junior, Antônio Paulo, Veiga, Viviane Cordeiro, Pereira, Adriano José, Cavalcanti, Alexandre Biasi

“…RESUMO Fundamentos Pacientes críticos têm maior risco de infecções relacionadas à assistência à saúde devido ao uso de vários dispositivos (infecção da…”
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Estudo randomizado prospectivo e controlado de avaliação dos efeitos de uma estratégia de limitação da driving pressure em pacientes com síndrome do desconforto respiratório agudo devido à pneumonia adquirida na comunidade (estudo STAMINA): protocolo e plano de análise estatística by Maia, Israel Silva, Medrado Jr, Fernando Azevedo, Tramujas, Lucas, Tomazini, Bruno Martins, Oliveira, Júlia Souza, Sady, Erica Regina Ribeiro, Barbante, Letícia Galvão, Nicola, Marina Lazzari, Gurgel, Rodrigo Magalhães, Damiani, Lucas Petri, Negrelli, Karina Leal, Miranda, Tamiris Abait, Santucci, Eliana, Valeis, Nanci, Laranjeira, Ligia Nasi, Westphal, Glauco Adrieno, Fernandes, Ruthy Perotto, Zandonai, Cássio Luis, Pincelli, Mariangela Pimentel, Figueiredo, Rodrigo Cruvinel, Bustamante, Cíntia Loss Sartori, Norbin, Luiz Fernando, Boschi, Emerson, Lessa, Rafael, Romano, Marcelo Pereira, Miura, Mieko Cláudia, Alencar Filho, Meton Soares de, Dantas, Vicente Cés de Souza, Barreto, Priscilla Alves, Hernandes, Mauro Esteves, Grion, Cintia Magalhães Carvalho, Laranjeira, Alexandre Sanches, Mezzaroba, Ana Luiza, Bahl, Marina, Starke, Ana Carolina, Biondi, Rodrigo Santos, Dal-Pizzol, Felipe, Caser, Eliana Bernadete, Thompson, Marlus Muri, Padial, Andrea Allegrini, Veiga, Viviane Cordeiro, Leite, Rodrigo Thot, Araújo, Gustavo, Guimarães, Mário, Martins, Priscilla de Aquino, Lacerda, Fábio Holanda, Hoffmann Filho, Conrado Roberto, Melro, Livia, Pacheco, Eduardo, Ospina-Táscon, Gustavo Adolfo, Ferreira, Juliana Carvalho, Freires, Fabricio Jocundo Calado, Machado, Flávia Ribeiro, Cavalcanti, Alexandre Biasi, Zampieri, Fernando Godinho

“…RESUMO Contexto: Em estudos observacionais sobre a síndrome do desconforto respiratório agudo, sugeriu-se que a driving pressure é o principal fator de lesão…”
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Antivirais para pacientes adultos hospitalizados com infecção por SARS-CoV-2: Um estudo de Fase II/III, randomizado, multicêntrico, controlado por placebo, adaptativo, com múltiplos braços e estágios. COALITION COVID-19 BRAZIL IX - REVOLUTIOn: protocolo e plano de análise estatística by Israel Silva Maia, Aline Marcadenti, Fernando Godinho Zampieri, Lucas Petri Damiani, Renato Hideo Nakagawa Santos, Karina Leal Negrelli, Samara Pinheiro do Carmo Gomes, Jaqueline Oliveira Gomes, Mariana Barbosa dos Santos Carollo, Tamiris Abait Miranda, Eliana Santucci, Nanci Valeis, Ligia Nasi Laranjeira, Glauco Adrieno Westphal, Jacques Gabriel Alvares Horta, Uri Adrian Prync Flato, Camilo Fernandes, Waldemar Carlos Barros, Renata S Bolan, Otávio Celso Eluf Gebara, Meton Soares de Alencar Filho, Victor Augusto Hamamoto, Mauro Esteves Hernandes, Nicole Alberti Golin, Ronald Torres de Olinda, Flávia Ribeiro Machado, Régis Goulart Rosa, Viviane Cordeiro Veiga, Luciano César Pontes de Azevedo, Alvaro Avezum, Renato Delascio Lopes, Tiago Moreno L Souza, Otávio Berwanger, Alexandre Biasi Cavalcanti

“…RESUMO Os medicamentos reaproveitados são importantes em contextos de recursos limitados porque as intervenções estão mais rapidamente disponíveis, já foram…”
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