Search Results - "Negreş, Simona"
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INVESTIGATION OF ANTIHYPERALGESIC EFFECTS OF DIFFERENT DOSES OF SILDENAFIL AND METFORMIN IN ALLOXAN-INDUCED DIABETIC NEUROPATHY IN MICE
Published in Farmacia (București) (29-06-2023)Get full text
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A Survey of Plant Iron Content-A Semi-Systematic Review
Published in Nutrients (10-12-2015)“…Iron is an essential mineral nutrient for all living organisms, involved in a plurality of biological processes. Its deficit is the cause of the most common…”
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Exploring the Therapeutic Potential of N-Methyl-D-Aspartate Receptor Antagonists in Neuropathic Pain Management
Published in International journal of molecular sciences (16-10-2024)“…Neuropathic pain (NeP) is a complex and debilitating condition that impacts millions of people globally. Although various treatment options exist, their…”
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Recent Progress in Gels for Neuropathic Pain
Published in Gels (16-05-2023)“…Neuropathic pain is a complex and debilitating condition that affects millions of people worldwide. While several treatment options are available, they often…”
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Ibuprofen, a drug used in pain, inflammation and fever
Published in Revista română de pediatrie (31-03-2019)“…Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid, used on a large scale both in adults and children for the treatment of…”
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Exploring the Multifaceted Potential of Sildenafil in Medicine
Published in Medicina (Kaunas, Lithuania) (01-12-2023)“…Phosphodiesterase type 5 (PDE5) is pivotal in cellular signalling, regulating cyclic guanosine monophosphate (cGMP) levels crucial for smooth muscle relaxation…”
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Author Correction: The development of a scoring and ranking strategy for a patient-tailored adverse drug reaction prediction in polypharmacy
Published in Scientific reports (09-03-2021)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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The development of a scoring and ranking strategy for a patient-tailored adverse drug reaction prediction in polypharmacy
Published in Scientific reports (12-06-2020)“…Only few applications are currently dealing with personalized adverse drug reactions (ADRs) prediction in case of polypharmacy. The study aimed to develop a…”
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Very Fast RP–UHPLC–PDA Method for Identification and Quantification of the Cannabinoids from Hemp Oil
Published in Applied sciences (01-10-2021)“…In recent years, hemp oils have become ubiquitous in health products on the European market. As the trend continues to grow and more cannabinoids are…”
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IDENTIFICATION AND QUANTIFICATION OF RISK FACTORS RELATED TO THE QUALITY OF LIFE OF MULTIPLE SCLEROSIS PATIENTS
Published in Farmacia (București) (30-10-2021)Get full text
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THE DEVELOPMENT AND VALIDATION OF A DISABILITY AND OUTCOME PREDICTION ALGORITHM IN MULTIPLE SCLEROSIS PATIENTS
Published in Farmacia (București) (21-12-2020)Get full text
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Evaluating the Antihyperalgesic Potential of Sildenafil-Metformin Combination and Its Impact on Biochemical Markers in Alloxan-Induced Diabetic Neuropathy in Rats
Published in Pharmaceuticals (Basel, Switzerland) (14-06-2024)“…(1) Background: Globally, about 600 million people are afflicted with diabetes, and one of its most prevalent complications is neuropathy, a debilitating…”
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The Influence of Sildenafil–Metformin Combination on Hyperalgesia and Biochemical Markers in Diabetic Neuropathy in Mice
Published in Medicina (Kaunas, Lithuania) (27-07-2023)“…Background and objectives: Worldwide, approximately 500 million people suffer from diabetes and at least 50% of these people develop neuropathy. Currently,…”
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The use of structural alerts to avoid the toxicity of pharmaceuticals
Published in Toxicology reports (01-01-2018)“…In order to identify compounds with potential toxicity problems, particular attention is paid to structural alerts, which are high chemical reactivity…”
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Natural Active Ingredients and TRPV1 Modulation: Focus on Key Chemical Moieties Involved in Ligand-Target Interaction
Published in Plants (Basel) (11-01-2023)“…Diseases such as cancer, neurological pathologies and chronic pain represent currently unmet needs. The existing pharmacotherapeutic options available for…”
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Ibuprofen, un medicament utilizat în durere, inflamaţie şi febră
Published in Practica farmaceutică (Online) (31-03-2019)Get full text
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UTILIZAREA IBUPROFENULUI ÎN FEBRĂ, DURERE ŞI INFLAMAŢIE LA COPII
Published in Revista română de pediatrie (31-03-2019)Get full text
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Switching Rat Resident Macrophages from M1 to M2 Phenotype by Iba1 Silencing Has Analgesic Effects in SNL-Induced Neuropathic Pain
Published in International journal of molecular sciences (01-11-2023)“…Resident macrophages from dorsal root ganglia are important for the development of traumatic-induced neuropathic pain. In the first 5–7 days after a traumatic…”
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In Silico Drug Repurposing Framework Predicts Repaglinide, Agomelatine and Protokylol as TRPV1 Modulators with Analgesic Activity
Published in Pharmaceutics (22-11-2022)“…Pain is one of the most common symptoms experienced by patients. The use of current analgesics is limited by low efficacy and important side effects. Transient…”
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EVALUATING THE SYNERGISM BETWEEN SILDENAFIL AND METFORMIN IN AN ANIMAL MODEL OF DIABETIC NEUROPATHY INDUCED BY ALLOXAN
Published in Farmacia (București) (31-08-2023)Get full text
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