Search Results - "Negi, Vijay"

Thymic precursor cells generate acute myeloid leukemia in NUP98-PHF23/NUP98-HOXD13 double transgenic mice by Kundu, Subhadip, Park, Eun Sil, Chung, Yang Jo, Walker, Robert L., Zhu, Yuelin J., Negi, Vijay, Meltzer, Paul S., Aplan, Peter D.

“…Transgenic mice that express either a NUP98–PHF23 (NP23) or NUP98-HOXD13 (NHD13) fusion in the hematopoietic compartment develop a wide spectrum of leukemias,…”
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A murine model for human early/immature T-cell precursor acute lymphoblastic leukemia (EITP ALL) by Negi, Vijay, Aplan, Peter D.

“…Early/immature T cell precursor acute lymphoblastic leukemia (EITP ALL) represents a subset of human leukemias distinct from other T-ALL, and associated with…”
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Idh2R140Q Cooperates with NHD13 to Induce Immature T Cell Leukemia By Targeting Early T Cell Progenitors or DN2 Thymocytes by Negi, Vijay, Goldberg, Liat, Chung, Yang Jo, Onozawa, Masahiro, Aplan, Peter D.

“…Introduction Mutations in the isocitrate dehydrogenase 1 (IDH1) and IDH2 genes are frequently observed in patients with acute myeloid leukemia, with IDH2…”
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NUP98::Nsd1 and FLT3-ITD collaborate to generate acute myeloid leukemia by Matsukawa, Toshihiro, Yin, Mianmian, Nigam, Nupur, Negi, Vijay, Li, Li, Small, Donald, Zhu, Yuelin J., Walker, Robert L., Meltzer, Paul S., Aplan, Peter D.

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Hoxa9 and Hoxa10 Induce CML Myeloid Blast Crisis Development through Activation of Myb Expression by Negi, Vijay, Vishwakarma, Bandana Ajay, Chu, Su, Oakley, Kevin, Han, Yufen, Bhatia, Ravi, Du, Yang

“…Mechanisms underlying the progression of Chronic Myeloid Leukemia (CML) from chronic phase to myeloid blast crisis are poorly understood. Our previous studies…”
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Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL by Goldberg, Liat, Negi, Vijay, Chung, Yang Jo, Onozawa, Masahiro, Zhu, Yuelin J, Walker, Robert L, Pierce, Rachel, Patel, Daxesh P, Krausz, Kristopher W, Gonzalez, Frank J, Goodell, Margaret A, Rodriguez, Benjamin A T, Meltzer, Paul S, Aplan, Peter D

“…Mutations in the isocitrate dehydrogenase 1 ( ) and genes are frequently observed in a wide variety of hematologic malignancies, including myeloid and T-cell…”
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Mutant IL-7Rα and mutant NRas are sufficient to induce murine T cell acute lymphoblastic leukemia by Cramer, Sarah D., Hixon, Julie A., Andrews, Caroline, Porter, Ross J., Rodrigues, Gisele O. L., Wu, Xiaolin, Back, Tim, Czarra, Kelli, Michael, Helen, Cam, Maggie, Chen, Jack, Esposito, Dominic, Senkevitch, Emilee, Negi, Vijay, Aplan, Peter D., Li, Wenqing, Durum, Scott K.

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Hoxa9 and Hoxa10 induce CML myeloid blast crisis development through activation of Myb expression by Negi, Vijay, Vishwakarma, Bandana A, Chu, Su, Oakley, Kevin, Han, Yufen, Bhatia, Ravi, Du, Yang

“…Mechanisms underlying the progression of Chronic Myeloid Leukemia (CML) from chronic phase to myeloid blast crisis are poorly understood. Our previous studies…”
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Runx1 repression by histone deacetylation is critical for Setbp1-induced mouse myeloid leukemia development by Vishwakarma, B A, Nguyen, N, Makishima, H, Hosono, N, Gudmundsson, K O, Negi, V, Oakley, K, Han, Y, Przychodzen, B, Maciejewski, J P, Du, Y

“…Abnormal activation of SETBP1 through overexpression or missense mutations is highly recurrent in various myeloid malignancies; however, it is unclear whether…”
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