Search Results - "Neggers, S J C M M"

The Introduction of the IDS-iSYS Total IGF-1 Assay May Have Far-Reaching Consequences for Diagnosis and Treatment of GH Deficiency by Varewijck, A. J, Lamberts, S. W. J, van der Lely, A. J, Neggers, S. J. C. M. M, Hofland, L. J, Janssen, J. A. M. J. L

“…Context: IGF-1 measurements are used for screening and monitoring GH deficiency (GHD) and acromegaly. Objective: Our objective was to study whether the…”
Get full text

Long-Term Efficacy and Safety of Pegvisomant in Combination With Long-Acting Somatostatin Analogs in Acromegaly by Neggers, S. J. C. M. M, Franck, S. E, de Rooij, F. W. M, Dallenga, A. H. G, Poublon, R. M. L, Feelders, R. A, Janssen, J. A. M. J. L, Buchfelder, M, Hofland, L. J, Jørgensen, J. O. L, van der Lely, A. J

“…Background: Treatment for acromegaly patients with long-acting somatotropin release-inhibiting factor (LA-SRIF) often does not result in complete normalization…”
Get full text

Efficacy and safety of bariatric surgery for craniopharyngioma-related hypothalamic obesity: a matched case–control study with 2 years of follow-up by Wijnen, M, Olsson, D S, van den Heuvel-Eibrink, M M, Wallenius, V, Janssen, J A M J L, Delhanty, P J D, van der Lely, A J, Johannsson, G, Neggers, S J C M M

“…Background: Hypothalamic obesity is a devastating consequence of craniopharyngioma. Bariatric surgery could be a promising therapeutic option. However, its…”
Get full text

Cushing's syndrome due to ectopic ACTH production by (neuroendocrine) prostate carcinoma by Alwani, R. A, Neggers, S. J. C. M. M, van der Klift, M, Baggen, M. G. A, van Leenders, G. J. L. H, van Aken, M. O, van der Lely, A. J, de Herder, W. W, Feelders, R. A

“…Ectopic adrenocorticotropin (ACTH) secretion accounts for less than 10% of all causes of endogenous Cushing's syndrome (CS) and is usually associated with…”
Get full text

Components of the metabolic syndrome in 500 adult long-term survivors of childhood cancer by van Waas, M., Neggers, S.J.C.M.M., Pieters, R., van den Heuvel-Eibrink, M.M.

“…Background: Adult survivors of childhood cancer have been reported to have an increased risk of late sequels. A cluster of abnormalities that contribute to the…”
Get full text

Quality of Life in Acromegalic Patients during Long-Term Somatostatin Analog Treatment with and without Pegvisomant by Neggers, S. J. C. M. M., van Aken, M. O., de Herder, W. W., Feelders, R. A., Janssen, J. A. M. J. L., Badia, X., Webb, S. M., van der Lely, A. J.

“…Objective: The objective of the study was to assess whether weekly administration of 40 mg pegvisomant (PEG-V) improves quality of life (QoL) and metabolic…”
Get full text

Bone mineral density after childhood cancer in 346 long-term adult survivors of childhood cancer by den Hoed, M. A. H., Klap, B. C., te Winkel, M. L., Pieters, R., van Waas, M., Neggers, S. J. C. M. M., Boot, A. M., Blijdorp, K., van Dorp, W., Pluijm, S. M. F., van den Heuvel-Eibrink, M. M.

“…Summary More than 45 % of long-term childhood cancer survivors (CCS) were diagnosed with osteopenia. Our data suggest that greater awareness for osteopenia is…”
Get full text

The role of AIP variants in pituitary adenomas and concomitant thyroid carcinomas in the Netherlands: a nationwide pathology registry (PALGA) study by Coopmans, E. C., Muhammad, A., Daly, A. F., de Herder, W. W., van Kemenade, F. J., Beckers, A., de Haan, M., van der Lely, A. J., Korpershoek, E., Neggers, S. J. C. M. M.

“…Purpose Germline mutations in the aryl-hydrocarbon receptor interacting protein ( AIP ) have been identified often in the setting of familial isolated…”
Get full text

Combined treatment for acromegaly with long-acting somatostatin analogs and pegvisomant: long-term safety for up to 4.5 years (median 2.2 years) of follow-up in 86 patients by Neggers, SJCMM, de Herder, WW, Janssen, JAMJL, Feelders, RA, van der Lely, AJ

“…BackgroundWe previously reported on the efficacy, safety, and quality of life (QoL) of long-acting somatostatin analogs (SSA) and (twice) weekly pegvisomant…”
Get full text

The effect of hypopituitarism on fatigue after subarachnoid hemorrhage by Khajeh, L., Ribbers, G. M., Heijenbrok-Kal, M. H., Blijdorp, K., Dippel, D. W. J., Sneekes, E. M., van den Berg-Emons, H. J. G., van der Lely, A. J., Neggers, S. J. C. M. M., van Kooten, F.

“…Background and purpose Aneurysmal subarachnoid hemorrhage (SAH) survivors often complain of fatigue, which is disabling. Fatigue is also a common symptom of…”
Get full text

Decreased ovarian function is associated with obesity in very long-term female survivors of childhood cancer by van Dorp, W, Blijdorp, K, Laven, J S E, Pieters, R, Visser, J A, van der Lely, A J, Neggers, S J C M M, van den Heuvel-Eibrink, M M

“…ObjectiveObesity and gonadal dysfunction are known major side effects of treatment in adult childhood cancer survivors (CCS). In the general population,…”
Get full text

What is active acromegaly and which parameters do we have? by Neggers, S. J. C. M. M., Biermasz, N. R., van der Lely, A. J.

“…Summary Disease activity of acromegaly can be measured in many ways. Growth hormone (GH) and insulin‐like growth factor 1 (IGF1) concentrations are the main…”
Get full text

Endocrine late sequelae in long-term survivors of childhood non-Hodgkin lymphoma by van Waas, M., Neggers, S.J.C.M.M., te Winkel, M.L., Beishuizen, A., Pieters, R., van den Heuvel-Eibrink, M.M.

“…Aim of this study was to investigate the long-term endocrine effects of treatment of childhood non-Hodgkin lymphoma (NHL). A single-center cohort of 84…”
Get full text

Metabolic syndrome detection with biomarkers in childhood cancer survivors by Pluimakers, V G, van Waas, M, Looman, C W N, de Maat, M P, de Jonge, R, Delhanty, P, Huisman, M, Mattace-Raso, F U S, van den Heuvel-Eibrink, M M, Neggers, S J C M M

“…Purpose: Augmented survival of childhood nephroblastoma and neuroblastoma has increased long-term side effects such as metabolic syndrome (MetS). Risk…”
Get full text

Metabolic syndrome as cardiovascular risk factor in childhood cancer survivors by Pluimakers, V.G., van Waas, M., Neggers, S.J.C.M.M., van den Heuvel-Eibrink, M.M.

“…[Display omitted] Over the past decades, survival rates of childhood cancer have increased considerably from 5 to 30% in the early seventies to current rates…”
Get full text

Longitudinal follow-up in female Childhood Cancer Survivors: no signs of accelerated ovarian function loss by van der Kooi, A.L.F., van den Heuvel-Eibrink, M.M., van Noortwijk, A., Neggers, S.J.C.M.M., Pluijm, S.M.F., van Dulmen-den Broeder, E., van Dorp, W., Laven, J.S.E.

“…STUDY QUESTION Is the long-term decline of ovarian function, as reflected by a decrease in serum anti-Müllerian hormone (AMH) concentration, accelerated over…”
Get full text

Combined treatment of somatostatin analogues with pegvisomant in acromegaly by Franck, S. E., Muhammad, A., van der Lely, A. J., Neggers, S. J. C. M. M.

“…Treatment of acromegaly with monotherapy long-acting somatostatin analogues (LA-SSA) as primary treatment or after neurosurgery can only achieve complete…”
Get full text

The influence of genetic variation on late toxicities in childhood cancer survivors: A review by Clemens, E., van der Kooi, A.L.F., Broer, L., van Dulmen-den Broeder, E., Visscher, H., Kremer, L., Tissing, W., Loonen, J., Ronckers, C.M., Pluijm, S.M.F., Neggers, S.J.C.M.M., Zolk, O., Langer, T., Zehnhoff-Dinnesen, A. am, Wilson, C.L., Hudson, M.M., Carleton, B., Laven, J.S.E., Uitterlinden, A.G., van den Heuvel-Eibrink, M.M.

“…The variability in late toxicities among childhood cancer survivors (CCS) is only partially explained by treatment and baseline patient characteristics…”
Get full text

Disagreement in normative IGF‐I levels may lead to different clinical interpretations and GH dose adjustments in GH deficiency by Varewijck, A.J., van der Lely, A.J., Neggers, S.J.C.M.M., Hofland, L.J., Janssen, J.A.M.J.L.

“…Summary Introduction and Background Normative data for the iSYS IGF‐I assay have been published both in the VARIETE cohort and by Bidlingmaier et al. Objective…”
Get full text

Discordant biological parameters of remission in acromegaly do not increase the risk of hypertension or diabetes: a study with the Liege Acromegaly Survey database by Amodru, V., Petrossians, P., Colao, A., Delemer, B., Maione, L., Neggers, S.J.C.M.M., Decoudier, B., Kamenicky, P., Castinetti, F., Hana, V., Pivonello, R., Carvalho, D., Brue, T., Beckers, A., Chanson, P., Cuny, T.

“…Purpose Acromegaly is a rare disease due to growth hormone (GH)-secreting pituitary adenoma. GH and IGF-1 levels are usually congruent, indicating either…”
Get full text