Search Results - "Neese, Richard A"

Delayed secretory pathway contributions to VLDL-triglycerides from plasma NEFA, diet, and de novo lipogenesis in humans by Vedala, Aruna, Wang, Wei, Neese, Richard A., Christiansen, Mark P., Hellerstein, Marc K.

“…Newly synthesized triglyceride (TG) may exit the liver immediately as VLDL-TG or be stored and secreted after a delay. We quantified the contributions from…”
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De novo lipogenesis, lipid kinetics, and whole-body lipid balances in humans after acute alcohol consumption by SILER, S. Q, NEESE, R. A, HELLERSTEIN, M. K

“…Acute alcohol intake is associated with changes in plasma lipid concentrations and whole-body lipid balances in humans. The quantitative roles of hepatic de…”
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Relationship between carbohydrate-induced hypertriglyceridemia and fatty acid synthesis in lean and obese subjects by Hudgins, L.C, Hellerstein, M.K, Seidman, C.E, Neese, R.A, Tremaroli, J.D, Hirsch, J

“…We previously reported that a eucaloric, low fat, liquid formula diet enriched in simple carbohydrate markedly increased the synthesis of fatty acids in lean…”
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Physiologic and Pharmacologic Factors Influencing Glyceroneogenic Contribution to Triacylglyceride Glycerol Measured by Mass Isotopomer Distribution Analysis by Chen, Jerry L, Peacock, Erin, Samady, Waheeda, Turner, Scott M, Neese, Richard A, Hellerstein, Marc K, Murphy, Elizabeth J

“…An imbalance between triacylglycerol synthesis and breakdown is necessary for the development of obesity. The direct precursor for triacylglycerol biosynthesis…”
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Measurement of Cell Proliferation by Labeling of DNA with Stable Isotope-Labeled Glucose: Studies in vitro, in Animals, and in Humans by Macallan, Derek C., Fullerton, Catherine A., Neese, Richard A., Haddock, Katherine, Park, Sunny S., Hellerstein, Marc K.

“…A method for measuring DNA synthesis and, thus, cell proliferation, in vivo is presented. The technique consists of administering [6,6-2H2]Glc or [U-13C]Glc,…”
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Measurement of cell proliferation by heavy water labeling by Hellerstein, Marc K, Busch, Robert, Neese, Richard A, Awada, Mohamad, Hayes, Gregory M

“…DNA replication occurs almost exclusively during S-phase of the cell cycle and represents a simple biochemical metric of cell division. Previous methods for…”
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The inhibition of gluconeogenesis following alcohol in humans by Siler, S.Q. (University of California, Berkeley, CA.), Neese, R.A, Christiansen, M.P, Hellerstein, M.K

“…Accurate quantification of gluconeogenic flux following alcohol ingestion in overnight-fasted humans has yet to be reported. [2-13C1]glycerol, [U-13C6]glucose,…”
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Measurement of protein turnover rates by heavy water labeling of nonessential amino acids by Busch, Robert, Kim, Yoo-Kyeong, Neese, Richard A., Schade-Serin, Valerie, Collins, Michelle, Awada, Mohamad, Gardner, James L., Beysen, Carine, Marino, Michael E., Misell, Lisa M., Hellerstein, Marc K.

“…In vivo measurements of protein synthesis using isotope-labeled amino acids (AAs) are hampered by the heterogeneity of AA pools and, for slow turnover…”
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Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection by Hellerstein, Marc K, Hoh, Rebecca A, Hanley, Mary Beth, Cesar, Denise, Lee, Daniel, Neese, Richard A, McCune, Joseph M

“…Antigenic stimulation of T cells gives rise to short-lived effector cells and long-lived memory cells. We used two stable isotope-labeling techniques to…”
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Mass isotopomer distribution analysis at eight years: theoretical, analytic, and experimental considerations by Hellerstein, M K, Neese, R A

“…Mass isotopomer distribution analysis (MIDA) is a technique for measuring the synthesis of biological polymers. First developed approximately eight years ago,…”
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VLDL-triglyceride production after alcohol ingestion, studied using [2-13C1] glycerol by Siler, S.Q. (University of California, Berkeley, CA.), Neese, R.A, Parks, E.J, Hellerstein, M.K

“…We used [2-13C1]glycerol to characterize very low density lipoprotein (VLDL)-triglyceride kinetics and intrahepatic glycerol metabolism in normal men (n = 4)…”
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Effects of a low-fat, high-carbohydrate diet on VLDL-triglyceride assembly, production, and clearance by Parks, E J, Krauss, R M, Christiansen, M P, Neese, R A, Hellerstein, M K

“…Low-fat, high-carbohydrate (LF/HC) diets commonly elevate plasma triglyceride (TG) concentrations, but the kinetic mechanisms responsible for this effect…”
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Dynamics of Keratinocytes in Vivo using 2H2O Labeling: A Sensitive Marker of Epidermal Proliferation State by Hsieh, Elaine A., Chai, Christine M., de Lumen, Benito O., Neese, Richard A., Hellerstein, Marc K.

“…A heavy water (2H2O) labeling method recently developed to measure cell proliferation in vivo is applied here to the measurement of murine epidermal cell…”
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The effect of dietary carbohydrate on genes for fatty acid synthase and inflammatory cytokines in adipose tissues from lean and obese subjects by Hudgins, Lisa C., Baday, Aline, Hellerstein, Marc K., Parker, Thomas S., Levine, Daniel M., Seidman, Cynthia E., Neese, Richard A., Tremaroli, Jolanta D., Hirsch, Jules

“…Hepatic de novo lipogenesis (DNL) is markedly stimulated in humans by low-fat diets enriched in simple sugars. However, the dietary responsiveness of the key…”
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Measurement of human plasma proteome dynamics with ²H₂O and liquid chromatography tandem mass spectrometry by Price, John C, Holmes, William E, Li, Kelvin W, Floreani, Nicholas A, Neese, Richard A, Turner, Scott M, Hellerstein, Marc K

“…Dysfunction of protein turnover is a feature of many human diseases, and proteins are substrates in important biological processes. Currently, no method exists…”
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Effect of nicotinic acid administration on hepatic very low density lipoprotein-triglyceride production by Wang, W, Basinger, A, Neese, R A, Shane, B, Myong, S A, Christiansen, M, Hellerstein, M K

“…Our objective was to examine very low density lipoprotein-triglyceride (VLDL-TG) kinetics after chronic and acute administration of nicotinic acid (NA)…”
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Lipoprotein Secretion and Triglyceride Stores in the Heart by Björkegren, Johan, Véniant, Murielle, Kim, Sun K., Withycombe, Shannon K., Wood, Philip A., Hellerstein, Marc K., Neese, Richard A., Young, Stephen G.

“…The genes for apolipoprotein B and microsomal triglyceride transfer protein are expressed in mouse and human heart tissue. Why the heart would express these…”
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Effects of isoenergetic overfeeding of either carbohydrate or fat in young men by Lammert, Ole, Grunnet, Niels, Faber, Peter, Bjørnsbo, Kirsten Schroll, Dich, John, Larsen, Lis Olesen, Neese, Richard A., Hellerstein, Marc K., Quistorff, Bjørn

“…Ten pairs of normal men were overfed by 5 MJ/d for 21 d with either a carbohydrate-rich or a fat-rich diet (C- and F-group). The two subjects in each pair were…”
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Effects of nicotinic acid on fatty acid kinetics, fuel selection, and pathways of glucose production in women by Wang, W, Basinger, A, Neese, R A, Christiansen, M, Hellerstein, M K

“…Chronic nicotinic acid (NA) ingestion effectively lowers lipid levels, but adverse effects on glucose metabolism have been reported. Our goal was to…”
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Effect of dietary energy restriction on glucose production and substrate utilization in type 2 diabetes by CHRISTIANSEN, Mark P, LINFOOT, Peter A, NEESE, Richard A, HELLERSTEIN, Marc K

“…Effect of dietary energy restriction on glucose production and substrate utilization in type 2 diabetes. M P Christiansen , P A Linfoot , R A Neese and M K…”
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