Search Results - "Neeraja, M"
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Fruit-In-Sight: A deep learning-based framework for secondary metabolite class prediction using fruit and leaf images
Published in PloS one (08-08-2024)“…Fruits produce a wide variety of secondary metabolites of great economic value. Analytical measurement of the metabolites is tedious, time-consuming, and…”
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A draft of the genome and four transcriptomes of a medicinal and pesticidal angiosperm Azadirachta indica
Published in BMC genomics (09-09-2012)“…The Azadirachta indica (neem) tree is a source of a wide number of natural products, including the potent biopesticide azadirachtin. In spite of its widespread…”
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Building flexible and robust analysis frameworks for molecular subtyping of cancers
Published in Molecular oncology (01-03-2024)“…Molecular subtyping is essential to infer tumor aggressiveness and predict prognosis. In practice, tumor profiling requires in‐depth knowledge of…”
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Utility of Acridine Orange staining for detection of bacteria from positive blood cultures
Published in Journal of microbiological methods (01-08-2017)“…The diagnostic performance of AO stain was evaluated for the detection of bacteria and or fungi from positive blood cultures. The sensitivity of Gram stain…”
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The mutational landscape of early‐ and typical‐onset oral tongue squamous cell carcinoma
Published in Cancer (15-02-2021)“…Background The incidence of oral tongue squamous cell carcinoma (OTSCC) is increasing among younger birth cohorts. The etiology of early‐onset OTSCC (diagnosed…”
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Messenger RNA expressing PfCSP induces functional, protective immune responses against malaria in mice
Published in npj vaccines (18-06-2021)“…Human malaria affects the vast majority of the world’s population with the Plasmodium falciparum species causing the highest rates of morbidity and mortality…”
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Surgical Tumor Resection Deregulates Hallmarks of Cancer in Resected Tissue and the Surrounding Microenvironment
Published in Molecular cancer research (04-06-2024)“…Surgery exposes tumor tissue to severe hypoxia and mechanical stress leading to rapid gene expression changes in the tumor and its microenvironment, which…”
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A Minimal DNA Methylation Signature in Oral Tongue Squamous Cell Carcinoma Links Altered Methylation with Tumor Attributes
Published in Molecular cancer research (01-09-2016)“…Oral tongue squamous cell carcinomas (OTSCC) are a homogenous group of aggressive tumors in the head and neck region that spread early to lymph nodes and have…”
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An Improved Genome Assembly of Azadirachta indica A. Juss
Published in G3 : genes - genomes - genetics (01-07-2016)“…Neem (Azadirachta indica A. Juss.), an evergreen tree of the Meliaceae family, is known for its medicinal, cosmetic, pesticidal and insecticidal properties. We…”
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Comparative analyses of putative toxin gene homologs from an Old World viper, Daboia russelii
Published in PeerJ (San Francisco, CA) (05-12-2017)“…Availability of snake genome sequences has opened up exciting areas of research on comparative genomics and gene diversity. One of the challenges in studying…”
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Functional genomics screen with pooled shRNA library and gene expression profiling with extracts of Azadirachta indica identify potential pathways for therapeutic targets in head and neck squamous cell carcinoma
Published in PeerJ (San Francisco, CA) (01-03-2019)“…Tumor suppression by the extracts of (neem) works via anti-proliferation, cell cycle arrest, and apoptosis, demonstrated previously using cancer cell lines and…”
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A minimal set of internal control genes for gene expression studies in head and neck squamous cell carcinoma
Published in PeerJ (San Francisco, CA) (14-08-2018)“…Selection of the right reference gene(s) is crucial in the analysis and interpretation of gene expression data. The aim of the present study was to discover…”
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COPS: a sensitive and accurate tool for detecting somatic Copy Number Alterations using short-read sequence data from paired samples
Published in PloS one (22-10-2012)“…Copy Number Alterations (CNAs) such as deletions and duplications; compose a larger percentage of genetic variations than single nucleotide polymorphisms or…”
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Unusual and rare manifestations of dengue during a dengue outbreak in a tertiary care hospital in South India
Published in Archives of virology (01-07-2014)“…Dengue is the most rapidly spreading mosquito-borne viral disease in the world, and as a larger proportion of the population is being affected, more unusual…”
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Augmenting transcriptome assembly by combining de novo and genome-guided tools
Published in PeerJ (San Francisco, CA) (15-08-2013)“…Researchers interested in studying and constructing transcriptomes, especially for non-model species, face the conundrum of choosing from a number of available…”
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Rapid detection and differentiation of dengue virus serotypes by NS1 specific reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay in patients presenting to a tertiary care hospital in Hyderabad, India
Published in Journal of virological methods (01-01-2015)“…•This research article highlights the development of an improved, inexpensive, faster, sensitive and specific RT-LAMP assay for detection and serotyping of…”
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Craniofacial morphology of HIV-infected adolescents undergoing highly active antiretroviral therapy (HAART): An original research
Published in Journal of Orthodontic Science (01-01-2020)“…OBJECTIVES: To analyze the craniofacial morphology in child patients and adolescents by evaluating the skeletal cephalometric profile of the HIV infected…”
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Mitochondrial replication origin stability and propensity of adjacent tRNA genes to form putative replication origins increase developmental stability in Lizards
Published in Journal of experimental zoology. Part B, Molecular and developmental evolution (15-09-2006)“…Secondary structure stability of mitochondrial origins of light‐strand replication (OL) presumably reduces delayed formation of light‐strand initiating…”
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A comparative approach to elucidate chloroplast genome replication
Published in BMC genomics (20-05-2009)“…Electron microscopy analyses of replicating chloroplast molecules earlier predicted bidirectional Cairns replication as the prevalent mechanism, perhaps…”
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RNAtor: an Android-based application for biologists to plan RNA sequencing experiments [version 2; peer review: 1 approved, 1 approved with reservations]
Published in F1000 research (2017)“…RNA sequencing (RNA-seq) is a powerful technology that allows one to assess the RNA levels in a sample. Analysis of these levels can help in identifying novel…”
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