Search Results - "Neely, M. D."

Cortical regulation of dopamine depletion-induced dendritic spine loss in striatal medium spiny neurons by Neely, M.D, Schmidt, D.E, Deutch, A.Y

“…Abstract The proximate cause of Parkinson’s disease is striatal dopamine depletion. Although no overt toxicity to striatal neurons has been reported in…”
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The Lipid Peroxidation Product 4‐Hydroxynonenal Inhibits Neurite Outgrowth, Disrupts Neuronal Microtubules, and Modifies Cellular Tubulin by Neely, M. D., Sidell, K. R., Graham, D. G., Montine, T. J.

“…: Oxidative stress is believed to be an important factor in the development of age‐related neurodegenerative diseases such as Alzheimer's disease (AD). The CNS…”
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Distribution of Reducible 4-Hydroxynonenal Adduct Immunoreactivity in Alzheimer Disease is Associated with APOE Genotype by Montine, Kathleen S, Reich, Erin, Neely, M Diana, Sidell, Kathrin R, Olson, Sandra J, Markesbery, William R, Montine, Thomas J

“…Two major risk factors for late-onset familial and sporadic Alzheimer disease (AD), a leading cause of dementia worldwide, are increasing age and inheritance…”
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CSF lipoproteins and Alzheimer's disease by Neely, M D, Montine, T J

“…Alterations in lipid homeostasis have been suggested to play a role in the pathogenesis of Alzheimer's disease (AD). This hypothesis is supported by the…”
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Motile areas of leech neurites are rich in microfilaments and two actin–binding proteins: gelsolin and profilin by Neely, M. D., MaCaluso, E.

“…Cell motility is produced by changes in the dynamics and organization of actin filaments. The aim of the experiments described here was to test whether growing…”
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Disruption of microfilaments in growth cones following depolarization and calcium influx by Neely, MD, Gesemann, M

“…Depolarization of leech neurons growing on extracellular matrix extract (ECM) leads to cessation of neurite outgrowth, rounding up of the peripheral regions of…”
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Sertoli Cell Processes Have Axoplasmic Features: An Ordered Microtubule Distribution and an Abundant High Molecular Weight Microtubule-Associated Protein (Cytoplasmic Dynein) by Neely, M. Diana, Boekelheide, Kim

“…Microtubules in the cytoplasm of rat Sertoli cell stage VI-VIII testicular seminiferous epithelium were studied morphometrically by electron microscopy. The…”
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Electrical activity, growth cone motility and the cytoskeleton by Neely, M D, Nicholls, J G

“…The development of the nervous system takes place in two main steps: first an extensive preliminary network is formed and then it is pruned and trimmed to…”
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Role of substrate and calcium in neurite retraction of leech neurons following depolarization by Neely, MD

“…The aim of these experiments was to analyze how depolarization influences neurite outgrowth in leech neurons and what role the substrate and Ca2+ play in this…”
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Human, but not bovine, oxidized cerebral spinal fluid lipoproteins disrupt neuronal microtubules by Neely, M. D., Swift, L. L., Montine, T. J.

“…Cerebral spinal fluid (CSF) lipoproteins have become a focus of research since the observation that inheritance of particular alleles of the apolipoprotein E…”
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HMW-2, the Sertoli cell cytoplasmic dynein from rat testis, is a dimer composed of nearly identical subunits by NEELY, M. D, ERICKSON, H. P, BOEKELHEIDE, K

“…The ultrastructure and biochemical characteristics of HMW-2, the Sertoli cell cytoplasmic dynein isolated from rat testes, were analyzed. Electron microscopic…”
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The Sertoli cell cytoskeleton: a target for toxicant-induced germ cell loss by Boekelheide, K, Neely, M D, Sioussat, T M

“…Numerous studies in recent years have elucidated fundamental properties of axoplasmic structure, biochemistry, and function. The structural role of the…”
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Cerebrospinal fluid lipoproteins are more vulnerable to oxidation in Alzheimer's disease and are neurotoxic when oxidized ex vivo by Bassett, Casey N., Neely, M. Diana, Sidell, Kathrin R., Markesbery, William R., Switt, Larry L., Montine, Thomas J.

“…Brain regional oxidative damage is thought to be a central mechanism in the pathogenesis of Alzheimer's disease (AD). Recent studies of cerebrospinal fluid…”
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Cerebrospinal fluid lipoproteins in Alzheimer's disease by Bassett, Casey N., Montine, Kathleen S., Neely, M. Diana, Swift, Larry L., Montine, Thomas J.

“…Interest in cerebrospinal fluid (CSF) lipoproteins has been stimulated by the association of certain alleles of the human apolipoprotein E gene (APOE) with an…”
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Impact of postoperative non-steroidal anti-inflammatory drugs on adverse events after gastrointestinal surgery by Chapman, S. J., Bhangu, A., Chaudhry, B., Clements, J. M., Robertson, K., Fadhlillah, M., Barker, T., Wright, T., Mohamad, W., Anderson, L. B., Brophy, T., Majumdar, S., Kauser, S., Carter, N., Horne, S., Allen, J. L. Y., Taylor, C., Satterthwaite, L., Hess, E. C. F., Finan, C., Ahmed, M., Grainger, C., Woo, A., Bulley, F., Aidoo‐Micah, G., Ellis, R., Kong, C. Y., Ochiltree, D. W., Hughes, M., Retchless, A. R., Bowley, D. M., Datta, U., Selby, J., Chandramoorthy, S., De Kauwe, C., Rana, R., Hill, M., Sagoo, H., Davis, J., Fillery, A., Watson, N. F., Marusza, C., Luck, J., Vaughan, R., Dean, S., Yap, D., Narramore, R., Walimohamed, S., Alsulaimi, A., Nepogodiev, D., Hernon, J., Flegg, K., Coley, J., Walls, M., Ban, V. S., Sait, S., Hawash, A., Shatkar, V., Moody, T., Shanthakumaran, S., Brodie, C., Winfield, S. Clayton A., Hosein, S., Cogbill, E., Shafi, A. M. A., Klimach, S., Flanigan, C., Shelton, B., Harvey, J., Pressler, N., Santos, C. R. D., Metcalfe, C., Mushtaq, J., Warren, M., Holohan, G., Strachan, E., Walsh, E., Mustafa, A., Barai, I., Soon, W. C., Patel, K., Mulla, A., Igbagiri, K. V., Navaratnam, J., Harrison, R., Hartelius, C. F., Lobo, R., Butters, T., Letchumanan, S., Koshnow, Z., Elamin, O., English, W., Brown, R. J., McCarter, J. A., Symonds, C., Jani, P., Trinquet, J., Jaffer, A., McAleer, E., Balian, V.

“…Background Recent evidence has suggested an association between postoperative non‐steroidal anti‐inflammatory drugs (NSAIDs) and increased operation‐specific…”
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Substrate-dependent interactions of leech microglial cells and neurons in culture by Masuda-Nakagawa, L M, Walz, A, Brodbeck, D, Neely, M D, Grumbacher-Reinert, S

“…The principal aim of the present experiments has been to analyze the properties of microglial cells and their role in nerve regeneration. In the leech, damage…”
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Retention and attempted mechanical transmission of Ehrlichia risticii by Stomoxys calcitrans by Burg, J G, Neely, D M, Williams, N M, Knapp, F W

“…The ability of adult Stomoxys calcitrans (L.) (Diptera: Muscidae) to retain viable Ehrlichia risticii (Rickettsiaceae), the aetiologic agent of Potomac horse…”
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Lipid peroxidation in aging brain and Alzheimer's disease by Montine, Thomas J, Neely, M Diana, Quinn, Joseph F, Beal, M Flint, Markesbery, William R, Roberts, L Jackson, Morrow, Jason D

“…Lipid peroxidation is one of the major outcomes of free radical-mediated injury that directly damages membranes and generates a number of secondary products,…”
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Lamotrigine-induced Sweet syndrome: Possible new drug association by Neely, Gabriel, Fajre, Ximena, Cabrera, Raúl, Castro, Alex

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Dual culprit for a swollen leg: Femoral vein compression caused by lymphadenopathy and a synovial cyst by Suzuki, Yota, Poli de Figueiredo, Sergio Mazzola, Keyhani, Arash, Tanaka, Akiko, Neely, Elaine, Keyhani, Kourosh

“…A young man had presented to the clinic with unilateral leg swelling with concerns for deep vein thrombosis. Imaging studies revealed external compression of…”
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