Search Results - "Neefs, Isabelle"
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Clinicopathological and molecular differences between stage IV screen-detected and interval colorectal cancers in the Flemish screening program
Published in Frontiers in oncology (02-09-2024)“…Interval cancer (IC) is an important quality indicator in colorectal cancer (CRC) screening. Previously, we found that fecal immunochemical test (FIT) ICs are…”
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Epigenome-wide methylation analysis of colorectal carcinoma, adenoma and normal tissue reveals novel biomarkers addressing unmet clinical needs
Published in Clinical epigenetics (06-07-2023)“…Biomarker discovery in colorectal cancer has mostly focused on methylation patterns in normal and colorectal tumor tissue, but adenomas remain understudied…”
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Towards Novel Non-Invasive Colorectal Cancer Screening Methods: A Comprehensive Review
Published in Cancers (10-04-2021)“…Colorectal cancer (CRC) is one of the leading cancer-related causes of death in the world. Since the 70s, many countries have adopted different CRC screening…”
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IMPRESS: Improved methylation profiling using restriction enzymes and smMIP sequencing, combined with a new biomarker panel, creating a multi-cancer detection assay
Published in British journal of cancer (19-10-2024)“…Background Despite the worldwide progress in cancer diagnostics, more sensitive diagnostic biomarkers are needed. The methylome has been extensively…”
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Simultaneous detection of eight cancer types using a multiplex droplet digital PCR assay
Published in Molecular oncology (06-09-2024)“…DNA methylation biomarkers have emerged as promising tools for cancer detection. Common methylation patterns across tumor types allow multi-cancer detection…”
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Journal Article