Search Results - "Nedrud, J"

T cell cytokine polarity as a determinant of immunoglobulin A (IgA) glycosylation and the severity of experimental IgA nephropathy by Chintalacharuvu, S.R, Yamashita, M, Bagheri, N, Blanchard, T.G, Nedrud, J.G, Lamm, M.E, Tomino, Y, Emancipator, S.N

“…Immunoglobulin A (IgA) glycosylation, recognized as an important pathogenic factor in IgA nephropathy (IgAN), is apparently controlled by the polarity of T…”
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Immunization of mice with urease vaccine affords protection against Helicobacter pylori infection in the absence of antibodies and is mediated by MHC class II-restricted responses by Ermak, T H, Giannasca, P J, Nichols, R, Myers, G A, Nedrud, J, Weltzin, R, Lee, C K, Kleanthous, H, Monath, T P

“…We examined the roles of cell- and antibody-mediated immunity in urease vaccine-induced protection against Helicobacter pylori infection. Normal and knockout…”
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Helicobacter-specific cell-mediated immune responses display a predominant Th1 phenotype and promote a delayed-type hypersensitivity response in the stomachs of mice by Mohammadi, M, Czinn, S, Redline, R, Nedrud, J

“…Studies regarding the nature of cell-mediated immunity in Helicobacter pylori infection and its role in pathogenesis have yielded controversial results. To…”
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Murine CD4 T-cell response to Helicobacter infection: TH1 cells enhance gastritis and TH2 cells reduce bacterial load by Mohammadi, M, Nedrud, J, Redline, R, Lycke, N, Czinn, SJ

“…BACKGROUND & AIMS: Previous findings suggest that TH1 cellular immune responses contribute to Helicobacter-associated gastritis. To further investigate this…”
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Long-Term Task- and Dopamine-Dependent Dynamics of Subthalamic Local Field Potentials in Parkinson's Disease by Hanrahan, Sara J, Nedrud, Joshua J, Davidson, Bradley S, Farris, Sierra, Giroux, Monique, Haug, Aaron, Mahoor, Mohammad H, Silverman, Anne K, Zhang, Jun Jason, Hebb, Adam Olding

“…Subthalamic nucleus (STN) local field potentials (LFP) are neural signals that have been shown to reveal motor and language behavior, as well as pathological…”
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T cell cytokines determine the severity of experimental IgA nephropathy by regulating IgA glycosylation by Chintalacharuvu, S. R., Nagy, N. U., Sigmund, N., Nedrud, J. G., Amm, M. E. L, Emancipator, S. N.

“…Hyperfunction of Th2 cells and aberrant glycosylation of IgA have been proposed independently as factors in the pathogenesis of IgA nephropathy (IgAN), the…”
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A new approach for automated detection of behavioral task onset for patients with Parkinson's disease using subthalamic nucleus local field potentials by Zaker, N., Zhang, J. J., Hanrahan, S., Nedrud, J., Hebb, A. O.

“…We present a new automated onset detection approach for behavioral tasks of patients with Parkinson's disease (PD) using Local Field Potential (LFP) signals…”
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Intracellular Neutralization of Virus by Immunoglobulin A Antibodies by Mazanec, Mary B., Kaetzel, Charlotte S., Lamm, Michael E., Fletcher, David, Nedrud, John G.

“…IgA is thought to neutralize viruses at the epithelial surface of mucous membranes by preventing their attachment. Since IgA, a polymeric immunoglobulin, is…”
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The role of nasal tolerance in a model of IgA nephropathy induced in mice by Sendai virus by Amore, A., Coppo, R., Nedrud, J.G., Sigmund, N., Lamm, M.E., Emancipator, S.N.

“…Mucosal antigenic exposure is implicated in pathogenesis of IgA nephropathy. Although IgG and/or IgM codeposits may promote disease, protracted mucosal…”
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Role of the host in pathogenesis of Helicobacter-associated gastritis: H. felis infection of inbred and congenic mouse strains by MOHAMMADI, M, REDLINE, R, NEDRUD, J, CZINN, S

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Therapeutic immunization against Helicobacter mustelae in naturally infected ferrets by Cuenca, R, Blanchard, TG, Czinn, SJ, Nedrud, JG, Monath, TP, Lee, CK, Redline, RW

“…BACKGROUND & AIMS: Helicobacter infection of the gastric antrum is responsible for a number of gastric disorders. Antibiotic therapy is lengthy and is not…”
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IgA Immunodeficiency Leads to Inadequate Th Cell Priming and Increased Susceptibility to Influenza Virus Infection by Arulanandam, Bernard P, Raeder, Roberta H, Nedrud, John G, Bucher, Doris J, Le, Jianhua, Metzger, Dennis W

“…IgA is considered to be the principal Ab involved in defense against pathogens in the mucosal compartment. Using mice with a targeted disruption in IgA gene…”
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Protection of germ-free mice from infection by Helicobacter felis after active oral or passive IgA immunization by Czinn, S J, Cai, A, Nedrud, J G

“…Helicobacter pylori infection of human gastric epithelium has been associated with gastritis, ulcers and gastric cancers. In an H. felis, germ-free mouse model…”
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Helicobacter pylori Vaccines: Lessons from Small Animal Models by Nedrud, J. G.

“…Helicobacter pylori is a highly mobile, gram negative microacerophile sprial bacterium which colonizes the antral region near the pylori valve of the human…”
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Clearance of Helicobacter pylori Infection and Resolution of Postimmunization Gastritis in a Kinetic Study of Prophylactically Immunized Mice by GARHART, Christine A, REDLINE, Raymond W, NEDRUD, John G, CZINN, Steven J

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Oral immunization against Helicobacter pylori by CZINN, S. J, NEDRUD, J. G

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Urease-specific monoclonal antibodies prevent Helicobacter felis infection in mice by Blanchard, T.G. (Case Western Reserve University, Cleveland, OH.), Czinn, S.J, Maurer, R, Thomas, W.D, Soman, G, Nedrud, J.G

“…Experiments were performed to determine the antigenic specificity of a monoclonal antibody (immunoglobulin A [IgA] 71) previously demonstrated to neutralize…”
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Vaccine-Induced Reduction of Helicobacter pylori Colonization in Mice Is Interleukin-12 Dependent but Gamma Interferon and Inducible Nitric Oxide Synthase Independent by GARHART, Christine A, HEINZEL, Frederick P, CZINN, Steven J, NEDRUD, John G

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Recombinant cholera toxin B subunit is not an effective mucosal adjuvant for oral immunization of mice against Helicobacter felis by Blanchard, T G, Lycke, N, Czinn, S J, Nedrud, J G

“…Cholera toxin is a potent oral mucosal adjuvant for enteric immunization. Several studies suggest that commercial cholera toxin B subunit (cCTB; purified from…”
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Vaccine-Induced Protection against Helicobacter pylori in Mice Lacking Both Antibodies and Interleukin-4 by GARHART, Christine A, NEDRUD, John G, HEINZEL, Frederick P, SIGMUND, Norma E, CZINN, Steven J

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