Search Results - "Nedorubov, Andrey"

Metabolic effects of vasopressin in pathophysiology of diabetic kidney disease by Lebedeva, Svetlana, Margaryan, Arus, Smolyarchuk, Elena, Nedorubov, Andrey, Materenchuk, Maria, Tonevitsky, Alexander, Mutig, Kerim

“…The diabetic kidney disease (DKD) is the major cause of the chronic kidney disease (CKD). Enhanced plasma vasopressin (VP) levels have been associated with the…”
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In FUS[1−359]‐tg mice O,S-dibenzoyl thiamine reduces muscle atrophy, decreases glycogen synthase kinase 3 beta, and normalizes the metabolome by Probert, Fay, Gorlova, Anna, Deikin, Alexei, Bettendorff, Lucien, Veniaminova, Ekaterina, Nedorubov, Andrey, Chaprov, Kirill D., Ivanova, Tamara A., Anthony, Daniel C., Strekalova, Tatyana

“…Mutations in the gene encoding the RNA/DNA-binding protein Fused in Sarcoma (FUS) have been detected in familial amyotrophic lateral sclerosis (ALS) patients…”
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Nocistatin and Products of Its Proteolysis Are Dual Modulators of Type 3 Acid-Sensing Ion Channels (ASIC3) with Algesic and Analgesic Properties by Osmakov, Dmitry I., Tarasova, Nadezhda V., Nedorubov, Andrey A., Palikov, Victor A., Palikova, Yulia A., Dyachenko, Igor A., Andreev, Yaroslav A., Kozlov, Sergey A.

“…The neuropeptide nocistatin (NS) is expressed by the nervous system cells and neutrophils as a part of a precursor protein and can undergo stepwise limited…”
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An experimental approach to comprehend the influence of platelet rich growth factors on spermatogenesis by Demyashkin, Grigory A., Borovaya, Tatyana G., Andreeva, Yulia Yu, Nedorubov, Andrey A., Stepanova, Yulia Yu, Vadyukhin, Matvey A., Shchekin, Vladimir I., Koryakin, Sergey N., Shegay, Peter V., Kaprin, Andrey D.

“…Leukocyte-poor platelet-rich plasma (LP-PRP) has a potential influence on tissue regeneration by stimulating the proliferation and differentiation of…”
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Insights into the Cardiotoxic Effects of Veratrum Lobelianum Alkaloids: Pilot Study by Taldaev, Amir, Terekhov, Roman P., Melnik, Elizaveta V., Belova, Maria V., Kozin, Sergey V., Nedorubov, Andrey A., Pomerantseva, Tatyana Ya, Ramenskaya, Galina V.

“…Jervine, protoveratrine A (proA), and protoveratrine B (proB) are Veratrum alkaloids that are presented in some remedies obtained from Veratrum lobelianum,…”
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Implantation of Various Cell-Free Matrixes Does Not Contribute to the Restoration of Hyaline Cartilage within Full-Thickness Focal Defects by Ibragimova, Shabnam I, Medvedeva, Ekaterina V, Romanova, Irina A, Istranov, Leonid P, Istranova, Elena V, Lychagin, Aleksey V, Nedorubov, Andrey A, Timashev, Peter S, Telpukhov, Vladimir I, Chagin, Andrei S

“…Articular cartilage is a highly organized tissue that has a limited ability to heal. Tissue engineering is actively exploited for joint tissue reconstruction…”
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Development of an Intranasal In Situ System for Ribavirin Delivery: In Vitro and In Vivo Evaluation by Mikhel, Iosif B, Bakhrushina, Elena O, Petrusevich, Danila A, Nedorubov, Andrey A, Appolonova, Svetlana A, Moskaleva, Natalia E, Demina, Natalia B, Kosenkova, Svetlana I, Parshenkov, Mikhail A, Krasnyuk, Jr, Ivan I, Krasnyuk, Ivan I

“…Recently, ribavirin has demonstrated effectiveness in treating glioblastoma through intranasal administration utilizing the nose-to-brain delivery route…”
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Impact of Serotonin Transporter Absence on Brain Insulin Receptor Expression, Plasma Metabolome Changes, and ADHD-like Behavior in Mice fed a Western Diet by Anthony, Daniel C, Probert, Fay, Gorlova, Anna, Hebert, Jenna, Radford-Smith, Daniel, Nefedova, Zlata, Umriukhin, Aleksei, Nedorubov, Andrey, Cespuglio, Raymond, Shulgin, Boris, Lyundup, Aleksey, Lesch, Klaus Peter, Strekalova, Tatyana

“…The impaired function of the serotonin transporter (SERT) in humans has been linked to a higher risk of obesity and type 2 diabetes, especially as people age…”
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Pharmacokinetic Properties of the Novel Synthetic Cannabinoid 5F-APINAC and Its Influence on Metabolites Associated with Neurotransmission in Rabbit Plasma by Shestakova, Ksenia M., Mesonzhnik, Natalia V., Markin, Pavel A., Moskaleva, Natalia E., Nedorubov, Andrey A., Brito, Alex, Appolonova, Elizaveta G., Kuznetsov, Roman M., Bochkareva, Natalia L., Kukharenko, Alexey, Lyundup, Alexey V., Tagliaro, Franco, Appolonova, Svetlana A.

“…The strong psychoactive effects of synthetic cannabinoids raise the need for the deeper studying of their neurometabolic effects. The pharmacokinetic…”
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Increased Oxidative Stress in the Prefrontal Cortex as a Shared Feature of Depressive- and PTSD-Like Syndromes: Effects of a Standardized Herbal Antioxidant by de Munter, Johannes, Pavlov, Dmitrii, Gorlova, Anna, Sicker, Michael, Proshin, Andrey, Kalueff, Allan V, Svistunov, Andrey, Kiselev, Daniel, Nedorubov, Andrey, Morozov, Sergey, Umriukhin, Aleksei, Lesch, Klaus-Peter, Strekalova, Tatyana, Schroeter, Careen A

“…Major depression (MD) and posttraumatic stress disorder (PTSD) share common brain mechanisms and treatment strategies. Nowadays, the dramatically developing…”
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A defined road to tracheal reconstruction: laser structuring and cell support for rapid clinic translation by Fayzullin, Alexey, Vladimirov, Georgiy, Kuryanova, Anastasia, Gafarova, Elvira, Tkachev, Sergei, Kosheleva, Nastasia, Istranova, Elena, Istranov, Leonid, Efremov, Yuri, Novikov, Ivan, Bikmulina, Polina, Puzakov, Kirill, Petrov, Pavel, Vyazankin, Ivan, Nedorubov, Andrey, Khlebnikova, Tatyana, Kapustina, Valentina, Trubnikov, Pavel, Minaev, Nikita, Kurkov, Aleksandr, Royuk, Valery, Mikhailov, Vasily, Parshin, Dmitriy, Solovieva, Anna, Lipina, Marina, Lychagin, Alexey, Timashev, Peter, Svistunov, Andrey, Fomin, Victor, Shpichka, Anastasia

“…Abstract One of the severe complications occurring because of the patient’s intubation is tracheal stenosis. Its incidence has significantly risen because of…”
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SARS-CoV-2 Subunit Virus-like Vaccine Demonstrates High Safety Profile and Protective Efficacy: Preclinical Study by Vakhrusheva, Anna V, Kudriavtsev, Aleksandr V, Kryuchkov, Nickolay A, Deev, Roman V, Frolova, Maria E, Blagodatskikh, Konstantin A, Djonovic, Milana, Nedorubov, Andrey A, Odintsova, Elena, Ivanov, Aleksandr V, Romanovskaya-Romanko, Ekaterina A, Stukova, Marina A, Isaev, Artur A, Krasilnikov, Igor V

“…Public health threat coming from a rapidly developing COVID-19 pandemic calls for developing safe and effective vaccines with innovative designs. This paper…”
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A randomized, double‐blind, comparative study of the pharmacodynamics and pharmacokinetics of GP40141 (romiplostim biosimilar) and reference romiplostim in healthy male volunteers by Makarenko, Igor, Dorotenko, Artem, Noskov, Sergey, Banko, Veniamin, Saparova, Valeria, Khokhlov, Alexandr, Zoreeva, Evgeniia, Nedorubov, Andrey, Zinnatulina, Bella, Gefen, Maria, Drai, Roman

“…Abstract Aims The pharmacodynamic (PD) similarity between GP40141, a proposed romiplostim biosimilar, and reference romiplostim was evaluated. Pharmacokinetics…”
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Latest developments in the pathobiology of Ewing sarcoma by Karlina, Irina, Schroeder, Brett A., Kirgizov, Kirill, Romantsova, Olga, Istranov, Andrey L., Nedorubov, Andrey, Timashev, Peter, Ulasov, Ilya

“…•Ewing sarcoma (ES) is an aggressive tumor with high rate of recurrency.•Combination therapy is effective but relapse and recurrence occurs.•More…”
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Comparative Efficiency of Gene-Activated Matrices Based on Chitosan Hydrogel and PRP Impregnated with BMP2 Polyplexes for Bone Regeneration by Nedorubova, Irina Alekseevna, Bukharova, Tatiana Borisovna, Mokrousova, Viktoria Olegovna, Khvorostina, Maria Aleksandrovna, Vasilyev, Andrey Vyacheslavovich, Nedorubov, Andrey Anatolevich, Grigoriev, Timofei Evgenevich, Zagoskin, Yuriy Dmitrievich, Chvalun, Sergei Nicolaevich, Kutsev, Sergey Ivanovich, Goldshtein, Dmitry Vadimovich

“…Gene therapy is one of the most promising approaches in regenerative medicine. Gene-activated matrices provide stable gene expression and the production of…”
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Predation stress causes excessive aggression in female mice with partial genetic inactivation of Tryptophan hydroxylase-2: evidence for altered myelination-related processes by Svirin, Evgeniy, Veniaminova, Ekaterina, da Costa Alvares Viegas Nunes, João Pedro, Gorlova, Anna, Umriukhin, Aleksei, Kalueff, Allan V., Proshin, Andrey, Anthony, Daniel C., Nedorubov, Andrey, Tse, Anna Chung Kwan, Walitza, Susanne, Lim, Lee Wei, Lesch, Klaus-Peter, Strekalova, Tatyana

“…© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative…”
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Adenovirus-Based Gene Therapy for Bone Regeneration: A Comparative Analysis of In Vivo and Ex Vivo BMP2 Gene Delivery by Bukharova, Tatiana Borisovna, Nedorubova, Irina Alekseevna, Mokrousova, Viktoria Olegovna, Meglei, Anastasiia Yurevna, Basina, Viktoriia Pavlovna, Nedorubov, Andrey Anatolevich, Vasilyev, Andrey Vyacheslavovich, Grigoriev, Timofei Evgenevich, Zagoskin, Yuriy Dmitrievich, Chvalun, Sergei Nicolaevich, Kutsev, Sergey Ivanovich, Goldshtein, Dmitry Vadimovich

“…Adenovirus-mediated gene therapy is a promising tool in bone regenerative medicine. In this work, gene-activated matrices (GAMs) composed of (1) polylactide…”
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Spontaneous remyelination following dimethyl sulfoxide-induced demyelination is accompanied by behavioral and neurological alteration in mice by Kudryashov, Nikita V., Gorbunov, Alexander A., Sviridkina, Nadezhda B., Mironov, Sergey E., Tikhonov, Dmitriy A., Nedorubov, Andrey A., Fisenko, Vladimir P.

“…Introduction: Dimethyl sulfoxide (DMSO) is a commonly used solvent that can be applied in experimental studies for preparation of hydrophobic solutions as well…”
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Immunogenicity and Protectivity of Sputnik V Vaccine in hACE2-Transgenic Mice against Homologous and Heterologous SARS-CoV-2 Lineages Including Far-Distanced Omicron BA.5 by Dolzhikova, Inna V, Tukhvatulin, Amir I, Grousova, Daria M, Zorkov, Ilya D, Komyakova, Marina E, Ilyukhina, Anna A, Kovyrshina, Anna V, Shelkov, Artem Y, Botikov, Andrey G, Samokhvalova, Ekaterina G, Reshetnikov, Dmitrii A, Siniavin, Andrey E, Savina, Daria M, Shcheblyakov, Dmitrii V, Izhaeva, Fatima M, Dzharullaeva, Alina S, Erokhova, Alina S, Popova, Olga, Ozharovskaya, Tatiana A, Zrelkin, Denis I, Goldovskaya, Polina P, Semikhin, Alexander S, Zubkova, Olga V, Nedorubov, Andrey A, Gushchin, Vladimir A, Naroditsky, Boris S, Logunov, Denis Y, Gintsburg, Alexander L

“…The SARS-CoV-2 virus continuously acquires mutations, leading to the emergence of new variants. Notably, the effectiveness of global vaccination efforts has…”
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Collagen–Platelet-Rich Plasma Mixed Hydrogels as a pBMP2 Delivery System for Bone Defect Regeneration by Meglei, Anastasiia Yurevna, Nedorubova, Irina Alekseevna, Basina, Viktoriia Pavlovna, Chernomyrdina, Viktoria Olegovna, Nedorubov, Andrey Anatolevich, Kuznetsova, Valeriya Sergeevna, Vasilyev, Andrey Vyacheslavovich, Kutsev, Sergey Ivanovich, Goldshtein, Dmitry Vadimovich, Bukharova, Tatiana Borisovna

“…Background/Objectives: The replenishment of bone deficiency remains a challenging task in clinical practice. The use of gene-activated matrices (GAMs)…”
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