Search Results - "Nedorezova, Daria D"
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Cationic Magnetite Nanoparticles for Increasing siRNA Hybridization Rates
Published in Nanomaterials (Basel, Switzerland) (27-05-2020)“…An investigation of the interaction principles of nucleic acids and nanoparticles is a priority for the development of theoretical and methodological…”
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2
Multicomponent DNAzyme Nanomachines: Structure, Applications, and Prospects
Published in Biochemistry (Moscow) (2024)“…Nucleic acids (NAs) are important components of living organisms responsible for the storage and transmission of hereditary information. They form complex…”
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3
Split light up aptamers as a probing tool for nucleic acids
Published in Methods (San Diego, Calif.) (01-01-2022)“…[Display omitted] •High selectivity of nucleic acid detection at ambient temperatures.•Detection of folded RNA under near physiological conditions.•Label-free…”
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Towards DNA Nanomachines for Cancer Treatment: Achieving Selective and Efficient Cleavage of Folded RNA
Published in Angewandte Chemie International Edition (26-03-2019)“…Despite decades of effort, gene therapy (GT) has failed to deliver clinically significant anticancer treatment, owing in part to low selectivity, low…”
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5
Deoxyribozyme‐Based DNA Machines for Cancer Therapy
Published in Chembiochem : a European journal of chemical biology (02-03-2020)“…Soon after their discovery, RNA‐cleaving deoxyribozymes (RCDZ) were explored as anticancer gene therapy agents. Despite low toxicity found in clinical trials,…”
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6
Cleaving Folded RNA by Multifunctional DNAzyme Nanomachines
Published in Chemistry : a European journal (16-07-2024)“…Both tight and specific binding of folded biological mRNA is required for gene silencing by oligonucleotide gene therapy agents. However, this is fundamentally…”
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7
Marker-dependent cleavage of RNA by binary (split) DNAzyme (BiDz) and binary DNA machines (biDNM)
Published in Chembiochem : a European journal of chemical biology (29-10-2024)“…Oligonucleotide gene therapy (OGT) can be used to suppress specific RNA in cells and thus have been explored for gene therapy. Despite extensive effort, there…”
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8
Cleaving Folded RNA with DNAzyme Agents
Published in Chembiochem : a European journal of chemical biology (02-01-2024)“…Cleavage of biological mRNA by DNAzymes (Dz) has been proposed as a variation of oligonucleotide gene therapy (OGT). The design of Dz‐based OGT agents includes…”
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9
Cascade of deoxyribozymes for the colorimetric analysis of drug resistance in Mycobacterium tuberculosis
Published in Biosensors & bioelectronics (01-10-2020)“…A visual cascade detection system has been applied to the detection and analysis of drug-resistance profile of Mycobacterium tuberculosis complex (MTC), a…”
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10
Specificity of oligonucleotide gene therapy (OGT) agents
Published in Theranostics (01-01-2022)“…Oligonucleotide gene therapy (OGT) agents (e. g. antisense, deoxyribozymes, siRNA and CRISPR/Cas) are promising therapeutic tools. Despite extensive efforts,…”
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11
Towards DNA Nanomachines for Cancer Treatment: Achieving Selective and Efficient Cleavage of Folded RNA
Published in Angewandte Chemie (26-03-2019)“…Despite decades of effort, gene therapy (GT) has failed to deliver clinically significant anticancer treatment, owing in part to low selectivity, low…”
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12
Towards Point of Care Diagnostics: Visual Detection of Meningitis Pathogens Directly from Cerebrospinal Fluid
Published in ChemistrySelect (Weinheim) (11-12-2020)“…Rapid and cost‐efficient methods for diagnostics of infectious diseases can expedite prescription of adequate treatment, thus shortening the patients’ recovery…”
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