Search Results - "Nedergaard, Mette K"

VEGF-C sustains VEGFR2 activation under bevacizumab therapy and promotes glioblastoma maintenance by Michaelsen, Signe R, Staberg, Mikkel, Pedersen, Henriette, Jensen, Kamilla E, Majewski, Wiktor, Broholm, Helle, Nedergaard, Mette K, Meulengracht, Christopher, Urup, Thomas, Villingshøj, Mette, Lukacova, Slávka, Skjøth-Rasmussen, Jane, Brennum, Jannick, Kjær, Andreas, Lassen, Ulrik, Stockhausen, Marie-Thérése, Poulsen, Hans S, Hamerlik, Petra

“…Glioblastoma ranks among the most lethal cancers, with current therapies offering only palliation. Paracrine vascular endothelial growth factor (VEGF)…”
Get full text

The use of longitudinal 18F-FET MicroPET imaging to evaluate response to irinotecan in orthotopic human glioblastoma multiforme xenografts by Nedergaard, Mette K, Kristoffersen, Karina, Michaelsen, Signe R, Madsen, Jacob, Poulsen, Hans S, Stockhausen, Marie-Thérése, Lassen, Ulrik, Kjaer, Andreas

“…Brain tumor imaging is challenging. Although 18F-FET PET is widely used in the clinic, the value of 18F-FET MicroPET to evaluate brain tumors in xenograft has…”
Get full text

Urokinase-Type Plasminogen Activator Receptor as a Potential PET Biomarker in Glioblastoma by Persson, Morten, Nedergaard, Mette K, Brandt-Larsen, Malene, Skovgaard, Dorthe, Jørgensen, Jesper T, Michaelsen, Signe R, Madsen, Jacob, Lassen, Ulrik, Poulsen, Hans S, Kjaer, Andreas

“…Glioblastoma is one of the most malignant types of human cancer, and the prognosis is poor. The development and validation of novel molecular imaging…”
Get full text

Targeting the Epidermal Growth Factor Receptor in Solid Tumor Malignancies by Nedergaard, Mette K., Hedegaard, Chris J., Poulsen, Hans S.

“…The epidermal growth factor receptor (EGFR) is over-expressed, as well as mutated, in many types of cancers. In particular, the EGFR variant type III mutant…”
Get full text

Abstract 5187: PET imaging of trastuzumab emtansine (T-DM1) drug delivery to intracranial patient derived xenograft (PDX) models of breast cancer metastasis by Nielsen, Carsten Haagen, Nedergaard, Mette K., Kristensen, Lotte K., Knudsen, Camilla S., Wick, Michael J., Papadopoulos, Kyri, Tolcher, Anthony, Kjaer, Andreas

“…Background: It is estimated that 10-30% of all breast cancer patients at some point develop brain metastases. Overexpression of the human epidermal growth…”
Get full text

Abstract 2805: A panel of orthotopic glioblastoma multiforme (GBM) patient derived xenograft (PDX) mouse models for efficacy evaluation of drugs by Jensen, Mette M., Knudsen, Camilla S., Kristensen, Lotte K., Nedergaard, Mette K., Wick, Michael J., Papadopoulos, Kyriakos P., Tolcher, Anthony W., Kjaer, Andreas, Nielsen, Carsten H.

“…Background: Patients with glioblastoma multiforme (GBM) have a poor prognosis and few treatment options; hence new treatments are needed. Subcutaneous patient…”
Get full text

Abstract 3227: Advanced imaging with PET and MRI in Temozolomide sensitive and resistant subcutaneous and orthotopic patient-derived xenograft (PDX) glioblastoma models by Nedergaard, Mette K., Nielsen, Carsten H., Papadopoulos, Kyriakos P., Tolcher, Anthony W., Wick, Michael J., Kjaer, Andreas

“…Background: Patients with glioblastoma multiforme (GBM) have a poor prognosis and few treatment options; hence new treatment strategies are needed. Recently,…”
Get full text

Abstract 4170: The role of VEGF-C for cell viability, tumor growth and bevacizumab resistance in glioblastoma multiforme by Michaelsen, Signe R., Nedergaard, Mette K., Urup, Thomas, Villingshoej, Mette, Kjaer, Andreas, Perryman, Lara, Erler, Janine T., Lassen, Ulrik, Poulsen, Hans S.

“…Although treatment with the VEGF-A targeting antibody Bevacizumab has resulted in substantial response rates in patients with the brain tumor Glioblastoma…”
Get full text

Abstract A15: Efficacy of trastuzumab emtansine (T-DM1) in subcutaneous and intracranial patient derived xenograft models of breast cancer metastasis by Nielsen, Carsten H., Nedergaard, Mette K., Kristensen, Lotte K., Knudsen, Camilla S., Wick, Michael J., Papadopoulos, Kyri, Tolcher, Anthony W., Kjaer, Andreas

“…Background: It is estimated that 10-30% of all breast cancer patients at some point develop brain metastases. Overexpression of the human epidermal growth…”
Get full text

The Use of Longitudinal .sup.18F-FET MicroPET Imaging to Evaluate Response to Irinotecan in Orthotopic Human Glioblastoma Multiforme Xenografts by Nedergaard, Mette K, Kristoffersen, Karina, Michaelsen, Signe R, Madsen, Jacob, Poulsen, Hans S, Stockhausen, Marie-Thérése, Lassen, Ulrik, Kjaer, Andreas

“…Objectives Brain tumor imaging is challenging. Although .sup.18 F-FET PET is widely used in the clinic, the value of .sup.18 F-FET MicroPET to evaluate brain…”
Get full text