Search Results - "Neckel, Peter H."
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Spatial gene expression profile of Wnt-signaling components in the murine enteric nervous system
Published in Frontiers in immunology (2024)“…Wnt-signaling is a key regulator of stem cell homeostasis, extensively studied in the intestinal crypt and other metazoan tissues. Yet, there is hardly any…”
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Evidence of SARS-CoV2 Entry Protein ACE2 in the Human Nose and Olfactory Bulb
Published in Cells, tissues, organs (2020)“…Usually, pandemic COVID-19 disease, caused by SARS-CoV2, presents with mild respiratory symptoms such as fever, cough, but frequently also with anosmia and…”
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Histological Evidence for the Enteric Nervous System and the Choroid Plexus as Alternative Routes of Neuroinvasion by SARS-CoV2
Published in Frontiers in neuroanatomy (06-10-2020)“…Evidence is mounting that the novel corona virus SARS-CoV2 inflicts neurological symptoms in a subgroup of COVID-19 patients. While plenty of theories on the…”
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Large-scale tissue clearing (PACT): Technical evaluation and new perspectives in immunofluorescence, histology and ultrastructure
Published in Scientific reports (29-09-2016)“…Novel techniques, like CLARITY and PACT, render large tissue specimens transparent and thereby suitable for microscopic analysis. We used these techniques to…”
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Overexpression of human alpha-Synuclein leads to dysregulated microbiome/metabolites with ageing in a rat model of Parkinson disease
Published in Molecular neurodegeneration (04-07-2023)“…Braak's hypothesis states that sporadic Parkinson's disease (PD) follows a specific progression of pathology from the peripheral to the central nervous system,…”
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Aquaporin-1 and Aquaporin-4 Expression in Ependyma, Choroid Plexus and Surrounding Transition Zones in the Human Brain
Published in Biomolecules (Basel, Switzerland) (22-01-2023)“…The choroid plexus (CP) is a structure in the brain ventricles that produces the main part of the cerebrospinal fluid (CSF). It is covered with specialized…”
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Dickkopf1 induces enteric neurogenesis and gliogenesis in vitro if apoptosis is evaded
Published in Communications biology (02-08-2023)“…Neurogenesis in the postnatal enteric nervous system (ENS) is controversially discussed. Yet, deciphering the regenerative potential of the ENS is essential…”
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Anatomical work-up of an individual with multiple muscular variants on both forearms
Published in Anatomical science international (01-09-2021)“…Muscular variants of the forearm are common and frequently cause neurovascular compression syndromes, especially when interfering with the compact topography…”
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A Cleared View on Retinal Organoids
Published in Cells (Basel, Switzerland) (28-04-2019)“…Human induced pluripotent stem cell (hiPSC)-derived organoids mimicking tissues and organs in vitro have advanced medical research, as they opened up new…”
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10
Restoring a natural skeleton of a premature infant from the early twentieth century
Published in Heritage science (03-09-2024)“…Traditional anatomical preparations as they are often found in university collections are both historical treasure and moral responsibility of the hosting…”
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Annotated translation of Georg Meissner's first description of the submucosal plexus
Published in Neurogastroenterology and motility (01-03-2023)“…Background The discovery and detailed descriptions of the enteric nervous system dates back only ˂200 years. The 19th century was a golden age of histological,…”
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Wnt Receptor Frizzled-4 as a Marker for Isolation of Enteric Neural Progenitors in Human Children
Published in Cells (Basel, Switzerland) (30-07-2019)“…Identification and isolation of neural progenitor cells from the human enteric nervous system (ENS) is currently hampered by the lack of reliable, specific…”
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Activation of Wnt Signaling Increases Numbers of Enteric Neurons Derived From Neonatal Mouse and Human Progenitor Cells
Published in Gastroenterology (New York, N.Y. 1943) (01-07-2017)“…Background & Aims Neural stem and progenitor cells from the enteric nervous system (ENS) might serve as a source of cells for treatment of…”
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14
Organization of radial glia reveals growth pattern in the telencephalon of a percomorph fish Astatotilapia burtoni
Published in Journal of comparative neurology (1911) (01-07-2021)“…In the brain of teleost fish, radial glial cells are the main astroglial cell type. To understand how radial glia structures are adapting to continuous growth…”
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XVIIth Little Brain Big Brain: an extraordinary meeting in extraordinary times
Published in Nature reviews. Gastroenterology & hepatology (01-04-2023)“…Little Brain Big Brain is a biannual meeting organized and attended by young investigators. Since its inception in 1989, this meeting has brought together…”
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16
Aquaporin-4 expression in the human choroid plexus
Published in Cellular and molecular life sciences : CMLS (01-02-2022)“…The choroid plexus (CP) consists of specialized ependymal cells and underlying blood vessels and stroma producing the bulk of the cerebrospinal fluid (CSF). CP…”
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Curricular representation of neurogastroenterology: A survey among medical students in Germany
Published in Neurogastroenterology and motility (01-10-2023)“…Neurogastroenterological disorders (NGDs) are highly prevalent and substantially impact patients' quality of life. Effective treatment of NGDs depends on the…”
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A modified pull-through approach with a pedicled bone flap for oral and oropharyngeal cancer resection: a feasibility study
Published in Surgical and radiologic anatomy (English ed.) (01-03-2024)“…Purpose Compromised swallowing, speaking, and local complications are the major disadvantages of established approaches to the posterior tongue and oropharynx…”
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Gut Analysis Toolbox: Automating quantitative analysis of enteric neurons
Published in Journal of cell science (15-10-2024)“…The enteric nervous system (ENS) consists of an extensive network of neurons and glial cells embedded within the wall of the gastrointestinal (GI) tract…”
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Organotypical Tissue Cultures from Fetal and Neonatal Murine Colon
Published in Methods in molecular biology (Clifton, N.J.) (2016)“…The complex functions of the gastrointestinal tract rely on the coordinated interplay of several cell and tissue types involving epithelium, connective tissue,…”
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