Search Results - "Near, Michelle"
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Do We Have Viable Protective Strategies against Anesthesia-Induced Developmental Neurotoxicity?
Published in International journal of molecular sciences (20-01-2022)“…Since its invention, general anesthesia has been an indispensable component of modern surgery. While traditionally considered safe and beneficial in many…”
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Neonatal ketamine exposure impairs infrapyramidal bundle pruning and causes lasting increase in excitatory synaptic transmission in hippocampal CA3 neurons
Published in Neurobiology of disease (01-12-2022)“…Preclinical models demonstrate that nearly all anesthetics cause widespread neuroapoptosis in the developing brains of infant rodents and non-human primates…”
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Neonatal sevoflurane exposure induces long-term changes in dendritic morphology in juvenile rats and mice
Published in Experimental biology and medicine (Maywood, N.J.) (01-04-2023)“…General anesthetics are potent neurotoxins when given during early development, causing apoptotic deletion of substantial number of neurons and persistent…”
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