Search Results - "Neale, Michael H."

Culture and Characterization of Oral Mucosal Epithelial Cells on a Fibrin Gel for Ocular Surface Reconstruction by Sheth, Radhika, Neale, Michael H., Shortt, Alex J., Massie, Isobel, Vernon, Amanda J., Daniels, Julie T.

“…Aim of the study: To develop a clinical grade fibrin gel for the culture of oral mucosal epithelial cells (OMEC) intended for ocular surface reconstruction in…”
Get full text

Generation of a persistently infected MDBK cell line with natural bovine spongiform encephalopathy (BSE) by Tark, Dongseob, Kim, Hyojin, Neale, Michael H, Kim, Minjeong, Sohn, Hyunjoo, Lee, Yoonhee, Cho, Insoo, Joo, Yiseok, Windl, Otto

“…Bovine spongiform encephalopathy (BSE) is a zoonotic transmissible spongiform encephalopathy (TSE) thought to be caused by the same prion strain as variant…”
Get full text

Enzymatic formulation capable of degrading scrapie prion under mild digestion conditions by Okoroma, Emeka A, Purchase, Diane, Garelick, Hemda, Morris, Roger, Neale, Michael H, Windl, Otto, Abiola, Oduola O

“…The prion agent is notoriously resistant to common proteases and conventional sterilisation procedures. The current methods known to destroy prion infectivity…”
Get full text

Infection of Cell Lines with Experimental and Natural Ovine Scrapie Agents by NEALE, Michael H, MOUNTJOY, Susan J, EDWARDS, Jane C, VILETTE, Didier, LAUDE, Hubert, WINDL, Otto, SAUNDERS, Ginny C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Detection and localisation of PrP(Sc) in the liver of sheep infected with scrapie and bovine spongiform encephalopathy by Everest, Sally J, Ramsay, Andrew M, Chaplin, Melanie J, Everitt, Sharon, Stack, Michael J, Neale, Michael H, Jeffrey, Martin, Moore, S Jo, Bellworthy, Susan J, Terry, Linda A

“…Prions are largely contained within the nervous and lymphoid tissue of transmissible spongiform encephalopathy (TSE) infected animals. However, following…”
Get full text

PIAS-1 Is a Checkpoint Regulator Which Affects Exit from G1 and G2 by Sumoylation of p73 by Munarriz, Eliana, Barcaroli, Daniela, Stephanou, Anastasis, Townsend, Paul A., Maisse, Carine, Terrinoni, Alessandro, Neale, Michael H., Martin, Seamus J., Latchman, David S., Knight, Richard A., Melino, Gerry, De Laurenzi, Vincenzo

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Outcome of ATP-based tumor chemosensitivity assay directed chemotherapy in heavily pre-treated recurrent ovarian carcinoma by Sharma, Sanjay, Neale, Michael H, Di Nicolantonio, Federica, Knight, Louise A, Whitehouse, Pauline A, Mercer, Stuart J, Higgins, Bernard R, Lamont, Alan, Osborne, Richard, Hindley, Andrew C, Kurbacher, Christian M, Cree, Ian A

“…We wished to evaluate the clinical response following ATP-Tumor Chemosensitivity Assay (ATP-TCA) directed salvage chemotherapy in a series of UK patients with…”
Get full text

Regulatory requirements in the good manufacturing practice production of an epithelial cell graft for ocular surface reconstruction by Sheth-Shah, Radhika, Vernon, Amanda J, Seetharaman, Shankar, Neale, Michael H, Daniels, Julie T

“…In the past decade, stem cell therapy has been increasingly employed for the treatment of various diseases. Subsequently, there has been a great interest in…”
Get full text

PrPSc is associated with B cells in the blood of scrapie-infected sheep by Edwards, Jane C, Moore, S. Jo, Hawthorn, Jeremy A, Neale, Michael H, Terry, Linda A

“…Abstract Recently, we reported that PrPSc , a surrogate marker for prion disease, is associated with the cellular fraction of blood from scrapie-infected sheep…”
Get full text

PrP(Sc) is associated with B cells in the blood of scrapie-infected sheep by Edwards, Jane C, Moore, S Jo, Hawthorn, Jeremy A, Neale, Michael H, Terry, Linda A

“…Recently, we reported that PrP(Sc), a surrogate marker for prion disease, is associated with the cellular fraction of blood from scrapie-infected sheep using a…”
Get full text

Detection and Localisation of PrPSc in the Liver of Sheep Infected with Scrapie and Bovine Spongiform Encephalopathy by Everest, Sally J., Ramsay, Andrew M., Chaplin, Melanie J., Everitt, Sharon, Stack, Michael J., Neale, Michael H., Jeffrey, Martin, Moore, S. Jo, Bellworthy, Susan J., Terry, Linda A.

“…Prions are largely contained within the nervous and lymphoid tissue of transmissible spongiform encephalopathy (TSE) infected animals. However, following…”
Get full text

TAp73α binds the kinetochore proteins Bub1 and Bub3 resulting in polyploidy by Vernole, Patrizia, Neale, Michael H., Barcaroli, Daniela, Munarriz, Eliana, Knight, Richard, Tomasini, Richard, Mak, Tak W., Melino, Gerry, De Laurenzi, Vincenzo

“…Aneuploidy is a characteristic of most solid tumors, often associated with negative prognosis. It can arise from two principal mechanisms: from a tetraploid…”
Get full text

Relationship between expression of topoisomerase II isoforms and chemosensitivity in choroidal melanoma by Satherley, Kirsten, de Souza, Lavinia, H. Neale, Michael, A. Alexander, Robert, Myatt, Nyree, J. E. Foss, Alex, L. Hungerford, John, D. Hickson, Ian, A. Cree, Ian

“…Choroidal melanoma has a high mortality rate and responds poorly to existing chemotherapy, but unexpected ex vivo sensitivity of a subset of these tumours to…”
Get full text

Abnormalities of the transforming growth factor-beta pathway in ocular melanoma by Myatt, Nyree, Aristodemou, Petros, Neale, Michael H., Foss, Alex J. E., Hungerford, John L., Bhattacharya, Shomi, A Cree, Ian

“…The majority of ocular melanomas occur in the uveal tract. Chemotherapy is generally ineffective and large tumours requiring enucleation have a greater than…”
Get full text

Treosulfan and gemcitabine by Cree, Ian A, Neale, Michael H, Reinhold, Uwe, Kurbacher, Christian M

Get full text

Heterogeneity of chemosensitivity of metastatic cutaneous melanoma by Cree, I A, Neale, M H, Myatt, N E, de Takats, P G, Hall, P, Grant, J, Kurbacher, C M, Reinhold, U, Neuber, K, MacKie, R M, Chana, J, Weaver, P C, Khoury, G G, Sartori, C, Andreotti, P E

“…Advanced melanoma has a poor prognosis and chemotherapy provides little benefit for most patients. This may be related to heterogeneity of chemosensitivity as…”
Get more information

Use of an ATP-based chemosensitivity assay to design new combinations of high-concentration doxorubicin with other drugs for recurrent ovarian cancer by Di Nicolantonio, Federica, Neale, Michael H, Knight, Louise A, Lamont, Alan, Skailes, Geraldine E, Osborne, Richard J, Allerton, Rosanne, Kurbacher, Christian M, Cree, Ian A

“…Liposomal doxorubicin (Caelyx/Doxil) has been shown to be active in around 20% of recurrent ovarian cancers. As yet, there is little clinical data on…”
Get full text

The ex vivo effect of high concentrations of doxorubicin on recurrent ovarian carcinoma by Neale, Michael H, Lamont, Alan, Hindley, Andrew, Kurbacher, Christian M, Cree, Ian A

“…The cardiotoxicity of anthracyclines has largely prevented dose intensification, but the use of liposomal preparations (e.g. Caelyx/Doxil) allows much higher…”
Get full text

Ex vivo activity of XR5000 against solid tumors by Neale, Michael H, Charlton, Peter A, Cree, Ian A

“…Topoisomerases I and II unravel DNA during transcription, DNA replication and DNA repair. Inhibitors of both enzymes are important anticancer drugs, but only…”
Get full text

PrP super(Sc) is associated with B cells in the blood of scrapie-infected sheep by Edwards, Jane C, Moore, SJo, Hawthorn, Jeremy A, Neale, Michael H, Terry, Linda A

“…Recently, we reported that PrP super(Sc), a surrogate marker for prion disease, is associated with the cellular fraction of blood from scrapie-infected sheep…”
Get full text