Search Results - "Neafsey, E J"

Combinatorial Preconditioning of Rat Brain Cultures with Subprotective Ethanol and Resveratrol Concentrations Promotes Synergistic Neuroprotection by Khodaie, N., Tajuddin, N., Mitchell, R. M., Neafsey, E. J., Collins, M. A.

“…Preconditioning brain cultures with moderate concentrations of ethanol (EtOH) or trans-resveratrol (RES), key red wine constituents, can prevent amyloid-β (Aβ)…”
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The effect of medial frontal cortex lesions on cardiovascular conditioned emotional responses in the rat by Frysztak, R J, Neafsey, E J

“…The effect of ventral medial frontal cortex (MFC) lesions on heart rate and blood pressure during conditioned emotional responses (CER) was investigated. Male…”
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Human Immunodeficiency Virus Type 1 gp120 and Ethanol Coexposure in Rat Organotypic Brain Slice Cultures: Curtailment of gp120-Induced Neurotoxicity and Neurotoxic Mediators by Moderate but not High Ethanol Concentrations by Belmadani, A, Neafsey, EJ, Collins, MA

“…Human immunodeficiency virus type 1 (HIV-1) envelope protein gp120, implicated with other retroviral proteins in acquired immunodeficiency syndrome…”
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Neuronal degeneration in rat cerebrocortical and olfactory regions during subchronic "binge" intoxication with ethanol: possible explanation for olfactory deficits in alcoholics by Collins, M A, Corso, T D, Neafsey, E J

“…Severe, repetitive ("binge") ethanol intoxication in adult rats (intragastric delivery 3 times daily for 4 days in a modification of the Majchrowicz method)…”
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Methyl-β-carbolinium analogs of MPP + cause nigrostriatal toxicity after substantia nigra injections in rats by Neafsey, E.J., Albores, R., Gearhart, D., Kindel, G., Raikoff, K., Tamayo, F., Collins, M.A.

“…Eleven β-carbolinium compounds (βC +s) and MPP + were stereotaxically injected (40–200 nmol in 5 μl of vehicle) unilaterally into the substantia nigra of…”
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Brain neuronal degeneration caused by episodic alcohol intoxication in rats : Effects of nimodipine, 6,7-dinitro-quinoxaline-2,3-dione, and MK-801 by CORSO, T. D, HISHAM MOHAMED MOSTAFA, COLLINS, M. A, NEAFSEY, E. J

“…Rats repeatedly intoxicated with alcohol (ethanol, three times daily) over a 4-day period display neuronal degeneration in the dentate gyrus; entorhinal,…”
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The organization of the rat motor cortex: a microstimulation mapping study by Neafsey, E J, Bold, E L, Haas, G, Hurley-Gius, K M, Quirk, G, Sievert, C F, Terreberry, R R

“…In conclusion, the rat primary motor cortex appears to be organized into irregularly shaped patches of cortex devoted to particular movements. The location of…”
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Mitochondrial Respiratory Inhibition by N-Methylated β-Carboline Derivatives Structurally Resembling N-Methyl-4-Phenylpyridine by Albores, Rudolph, Neafsey, Edward J., Drucker, George, Fields, Jeremy Z., Collins, Michael A.

“…Mitochondrial accumulation and respiratory inhibition are critical steps in the actions of N-methyl-4-phenylpyridinium ion (MPP+), the toxic metabolite of the…”
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Binge ethanol-induced brain damage in rats: effect of inhibitors of nitric oxide synthase by Zou, J Y, Martinez, D B, Neafsey, E J, Collins, M A

“…Testing the possible role of endogenous nitric oxide (NO) in the neurotoxicity of ethanol, we examined how two different NO synthase (NOS) inhibitors affected…”
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Potential bioactivated neurotoxicants, N-methylated beta-carbolinium ions, are present in human brain by Matsubara, K, Collins, M A, Akane, A, Ikebuchi, J, Neafsey, E J, Kagawa, M, Shiono, H

“…Potential bioactivated neurotoxicants, 2-N-methyl-beta-carbolinium and 2,9-N,N'-dimethyl-beta-carbolinium ions, as well as N-methylation activities which form…”
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Striatal dopaminergic toxicity following intranigral injection in rats of 2-methyl-norharman, a beta-carbolinium analog of N-methyl-4-phenylpyridinium ion (MPP+) by Neafsey, E J, Drucker, G, Raikoff, K, Collins, M A

“…Methylated beta-carboline compounds are mammalian indole metabolites that we have proposed to be endogenous neurotoxins due to their structural similarity to…”
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Indole-N-methylated beta-carbolinium ions as potential brain-bioactivated neurotoxins by Collins, M A, Neafsey, E J, Matsubara, K, Cobuzzi, Jr, R J, Rollema, H

“…N-Methyl-4-phenylpyridinium ion (MPP+), a highly toxic metabolite produced in the brain from a street drug contaminant, is selectively taken up by…”
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Hippocampal input to a visceral motor corticobulbar pathway : an anatomical and electrophysiological study in the rat by RUIT, K. G, NEAFSEY, E. J

“…The hippocampus has previously been shown to influence cardiovascular function, and this effect appears to be mediated by the connection the hippocampus has…”
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Cardiovascular and respiratory responses to electrical and chemical stimulation of the hippocampus in anesthetized and awake rats by Ruit, K G, Neafsey, E J

“…Electrical (30-60-s trains of 0.25-ms pulses at 25 Hz, currents 10-150 microA) and chemical (microinjections of 0.1-0.5 microliters of a 1.0 M glutamate…”
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Differential cytotoxicities of N-methyl-beta-carbolinium analogues of MPP+ in PC12 cells: insights into potential neurotoxicants in Parkinson's disease by Cobuzzi, Jr, R J, Neafsey, E J, Collins, M A

“…N-Methylated beta-carbolinium cations that can form in vivo from environmental or endogenous beta-carbolines are putative neurotoxic factors in Parkinson's…”
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Novel S-adenosylmethionine-dependent indole-N-methylation of beta-carbolines in brain particulate fractions by Matsubara, K, Neafsey, E J, Collins, M A

“…Guinea pig brain S-adenosylmethionine (SAM)-dependent N-methyltransferase activity toward physiologically relevant beta-carboline (BC) substrates was examined…”
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Functional Reorganization of the Motor Cortex in Adult Rats after Cortical Lesion and Treatment with Monoclonal Antibody IN-1 by Emerick, April J, Neafsey, Edward J, Schwab, Martin E, Kartje, Gwendolyn L

“…We previously reported anatomical plasticity in the adult motor cortex after a unilateral sensorimotor cortex (SMC) lesion and treatment with monoclonal…”
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Rat medial frontal cortex: a visceral motor region with a direct projection to the solitary nucleus by Terreberry, R R, Neafsey, E J

“…Pressure injections of the neuroanatomical tracer wheat germ agglutinin conjugated with HRP (WGA-HRP) were made into either the dorsal medulla or the medial…”
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A second forelimb motor area exists in rat frontal cortex by Neafsey, E J, Sievert, C

“…Intracortical microstimulation of 40--50 points in the frontal cortex of ketamine-anesthetized rats using perpendicular penetrations has demonstrated a second…”
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Dopamine uptake inhibitory capacities of beta-carboline and 3,4-dihydro-beta-carboline analogs of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) oxidation products by Drucker, G, Raikoff, K, Neafsey, E J, Collins, M A

“…Potentially endogenous beta-carboline and 3,4-dihydro-beta-carboline alkaloidal compounds were compared, generally as 2-methylated (quaternary) and…”
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