Search Results - "Ndugwa, Christopher M"

Burden of sickle cell trait and disease in the Uganda Sickle Surveillance Study (US3): a cross-sectional study by Ndeezi, Grace, MBChB PhD, Kiyaga, Charles, MSc MPhil, Hernandez, Arielle G, BA, Munube, Deogratias, MBChB, Howard, Thad A, MS, Ssewanyana, Isaac, MSc, Nsungwa, Jesca, MBChB PhD, Kiguli, Sarah, MBChB, Ndugwa, Christopher M, MBChB, Ware, Russell E, Dr, Aceng, Jane R, MBChB MPH

“…Summary Background Sickle cell disease contributes substantially to mortality in children younger than 5 years in sub-Saharan Africa. In Uganda, 20 000 babies…”
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Hydroxyurea to lower transcranial Doppler velocities and prevent primary stroke: the Uganda NOHARM sickle cell anemia cohort by Opoka, Robert O, Hume, Heather A, Latham, Teresa S, Lane, Adam, Williams, Olatundun, Tymon, Jennifer, Nakafeero, Maria, Kasirye, Phillip, Ndugwa, Christopher M, John, Chandy C, Ware, Russell E

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Hydroxyurea Dose Escalation for Sickle Cell Anemia in Sub-Saharan Africa by John, Chandy C, Opoka, Robert O, Latham, Teresa S, Hume, Heather A, Nabaggala, Catherine, Kasirye, Phillip, Ndugwa, Christopher M, Lane, Adam, Ware, Russell E

“…Hydroxyurea increases expression of fetal hemoglobin and decreases clinical complications in children with sickle cell anemia. A trial of a higher dose (30 mg…”
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Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia by Opoka, Robert O., Ndugwa, Christopher M., Latham, Teresa S., Lane, Adam, Hume, Heather A., Kasirye, Phillip, Hodges, James S., Ware, Russell E., John, Chandy C.

“…Hydroxyurea treatment is recommended for children with sickle cell anemia (SCA) living in high-resource malaria-free regions, but its safety and efficacy in…”
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Molecular Evidence for Mother-to-Child Transmission of Kaposi Sarcoma–Associated Herpesvirus in Uganda and K1 Gene Evolution within the Host by Mbulaiteye, Sam, Marshall, Vickie, Bagni, Rachel K., Wang, Cheng-Dian, Mbisa, Georgina, Bakaki, Paul M., Owor, Anchilla M., Ndugwa, Christopher M., Engels, Eric A., Katongole-Mbidde, Edward, Biggar, Robert J., Whitby, Denise

“…BackgroundEpidemiological studies of Kaposi sarcoma (KS)–related herpesvirus (KSHV) indicate that having a KSHV-seropositive mother is a risk factor for KSHV…”
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Presumptive treatment with sulphadoxine-pyrimethamine versus weekly chloroquine for malaria prophylaxis in children with sickle cell anaemia in Uganda: a randomized controlled trial by Nakibuuka, Victoria, Ndeezi, Grace, Nakiboneka, Deborah, Ndugwa, Christopher M, Tumwine, James K

“…Malaria carries high case fatality among children with sickle cell anaemia. In Uganda, chloroquine is used for prophylaxis in these children despite…”
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Effect of multiple micronutrient supplementation on survival of HIV‐infected children in Uganda: a randomized, controlled trial by Ndeezi, Grace, Tylleskär, Thorkild, Ndugwa, Christopher M, Tumwine, James K

“…Background Micronutrient deficiencies compromise the survival of HIV‐infected children in low‐income countries. We assessed the effect of multiple…”
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High Levels of Epstein-Barr Virus DNA in Saliva and Peripheral Blood from Ugandan Mother-Child Pairs by Mbulaiteye, Sam M., Walters, Michael, Engels, Eric A., Bakaki, Paul M., Ndugwa, Christopher M., Owor, Anchilla M., Goedert, James J., Whitby, Denise, Biggar, Robert J.

“…In Africa, Epstein-Barr virus (EBV) is associated with Burkitt lymphoma. We measured levels of EBV DNA in saliva and buffy coats from 233 asymptomatic Ugandan…”
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Hemoglobin variants identified in the Uganda Sickle Surveillance Study by Schaefer, Beverly A., Kiyaga, Charles, Howard, Thad A., Ndeezi, Grace, Hernandez, Arielle G., Ssewanyana, Isaac, Paniagua, Mary C., Ndugwa, Christopher M., Aceng, Jane R., Ware, Russell E.

“…The Uganda Sickle Surveillance Study analyzed dried blood spots that were collected from almost 100 000 infants and young children from all 10 regions and 112…”
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Zinc status in HIV infected Ugandan children aged 1-5 years: a cross sectional baseline survey by Ndeezi, Grace, Tumwine, James K, Bolann, Bjørn J, Ndugwa, Christopher M, Tylleskär, Thorkild

“…Low concentrations of serum zinc have been reported in HIV infected adults and are associated with disease progression and an increased risk of death. Few…”
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Detection of Kaposi Sarcoma—Associated Herpesvirus DNA in Saliva and Buffy-Coat Samples from Children with Sickle Cell Disease in Uganda by Mbulaiteye, Sam M., Pfeiffer, Ruth M., Engels, Eric A., Marshall, Vickie, Bakaki, Paul M., Owor, Anchilla M., Ndugwa, Christopher M., Katongole-Mbidde, Edward, Goedert, James J., Biggar, Robert J., Whitby, Denis

“…Among 233 children, Kaposi sarcoma-associated herpesvirus (KSHV) DNA was detected in 43% of children seropositive for both K8.1 and orf73, in 29% of children…”
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Sickle cell screening in Uganda: High burden, human immunodeficiency virus comorbidity, and genetic modifiers by Kiyaga, Charles, Hernandez, Arielle G., Ssewanyana, Isaac, Schaefer, Beverly A., McElhinney, Kathryn E., Ndeezi, Grace, Howard, Thad A., Ndugwa, Christopher M., Ware, Russell E., Aceng, Jane R.

“…Background The Uganda Sickle Surveillance Study provided evidence for a large sickle burden among HIV‐exposed infants in Uganda. To date, however, no large…”
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Hepatitis C virus genotype 4 in Ugandan children and their mothers by Biggar, Robert J, Ortiz-Conde, Betty A, Bagni, Rachel K, Bakaki, Paul M, Wang, Cheng-Dian, Engels, Eric A, Mbulaiteye, Sam M, Ndugwa, Christopher M

“…In Kampala, Uganda, in 2001, hepatitis C virus antibodies were found in 27 (4%) of 603 children and in 62 (12%) of 525 of their mothers. However, only…”
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HLA polymorphisms and detection of kaposi sarcoma-associated herpesvirus DNA in saliva and peripheral blood among children and their mothers in the uganda sickle cell anemia KSHV Study by Guech-Ongey, Mercy, Verboom, Murielle, Pfeiffer, Ruth M, Schulz, Thomas F, Ndugwa, Christopher M, Owor, Anchilla M, Bakaki, Paul M, Bhatia, Kishor, Figueiredo, Constança, Eiz-Vesper, Britta, Blasczyk, Rainer, Mbulaiteye, Sam M

“…Kaposi sarcoma-associated herpesvirus (KSHV, also called Human herpesvirus 8 or HHV8) is a γ-2 herpesvirus that causes Kaposi sarcoma. KSHV seroprevalence…”
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Plasma magnesium is inversely associated with Epstein-Barr virus load in peripheral blood and Burkitt lymphoma in Uganda by Juan, Ravell, Otim, Isaac, Nabalende, Hadijah, Legason, Ismail D., Reynolds, Steven J., Ogwang, Martin D., Ndugwa, Christopher M., Marshall, Vickie, Whitby, Denise, Goedert, James J., Engels, Eric A., Bhatia, Kishor, Lenardo, Michael J., Mbulaiteye, Sam M.

“…•XMEN disease involves intracellular Mg2+ deficiency, impaired EBV control, and high risk of lymphoma.•Ugandan women with poorly controlled EBV infection and…”
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Erratum to “Plasma magnesium is inversely associated with Epstein-Barr virus load in peripheral blood and Burkitt lymphoma in Uganda” [Cancer Epidemiol. 52 (2018) 70–74] by Ravell, Juan, Otim, Isaac, Nabalende, Hadijah, Legason, Ismail D., Reynolds, Steven J., Ogwang, Martin D., Ndugwa, Christopher M., Marshall, Vickie, Whitby, Denise, Goedert, James J., Engels, Eric A., Bhatia, Kishor, Lenardo, Michael J., Mbulaiteye, Sam M.

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Building a sickle cell disease screening program in the Republic of Uganda: the Uganda Sickle Surveillance Study (US3) with 3 years of follow-up screening results by Kiyaga, Charles, Hernandez, Arielle G., Ssewanyana, Isaac, McElhinney, Kathryn E., Ndeezi, Grace, Howard, Thad A., Ndugwa, Christopher M., Ware, Russell E., Aceng, Jane R.

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Alpha thalassemia among sickle cell anaemia patients in Kampala, Uganda by Lubega, Irene, Ndugwa, Christopher M, Mworozi, Edison A, Tumwine, James K

“…Background: Sickle cell anaemia is prevalent in sub Saharan Africa. While α+-thalassaemia is known to modulate sickle cell anaemia, its magnitude and…”
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Multiple micronutrient supplementation does not reduce diarrhoea morbidity in Ugandan HIV-infected children: a randomised controlled trial by Ndeezi, Grace, Tylleskar, Thorkild, Ndugwa, Christopher M, Tumwine, James K

“…Objectives: To determine the effect of multiple micronutrient supplementation on the incidence and prevalence of diarrhoea in Ugandan HIV-infected children…”
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Multiple micronutrient supplementation improves vitamin B12and folate concentrations of HIV infected children in Uganda: a randomized controlled trial by Ndeezi, Grace, Tumwine, James K, Ndugwa, Christopher M, Bolann, Bjørn J, Tylleskär, Thorkild

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