Search Results - "Ndhlovu, Chiratidzo E"
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Early versus Delayed Initiation of Antiretroviral Therapy for Concurrent HIV Infection and Cryptococcal Meningitis in Sub-Saharan Africa
Published in Clinical infectious diseases (01-06-2010)“…Background. Cryptococcal meningitis (CM) remains a leading cause of acquired immunodeficiency syndrome-related death in sub-Saharan Africa. The timing of the…”
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Drug resistance and optimizing dolutegravir regimens for adolescents and young adults failing antiretroviral therapy
Published in AIDS (London) (01-09-2019)“…OBJECTIVES:The integrase strand inhibitor dolutegravir (DTG) combined with tenofovir and lamivudine (TLD) is a single tablet regimen recommended for 1st, 2nd…”
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HIV status disclosure to perinatally-infected adolescents in Zimbabwe: a qualitative study of adolescent and healthcare worker perspectives
Published in PloS one (27-01-2014)“…Due to the scale up of antiretroviral therapy, increasing numbers of HIV-infected children are living into adolescence. As these children grow and surpass the…”
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Comparing pill counts and patient self-reports versus DBS tenofovir concentrations as ART adherence measurements with virologic outcomes and HIV drug resistance in a cohort of adolescents and young adults failing ART in Harare, Zimbabwe
Published in Journal of infection and public health (01-09-2024)“…Monitoring adherence presents a challenge in adolescents and it is prudent to explore several options for determining their level of adherence. This study…”
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Undiagnosed HIV Infection among Adolescents Seeking Primary Health Care in Zimbabwe
Published in Clinical infectious diseases (01-10-2010)“…Background. Mother-to-child transmission of human immunodeficiency virus (HIV) infection was extremely common in southern Africa during the 1990s, and a…”
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Tenofovir-associated kidney disease in Africans: a systematic review
Published in AIDS research and therapy (06-06-2019)“…Data on chronic kidney disease development in HIV infection is important towards building a comprehensive knowledge of HIV, ageing and polypharmacy in Africa…”
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Psychological distress among healthcare workers accessing occupational health services during the COVID-19 pandemic in Zimbabwe
Published in Comprehensive psychiatry (01-07-2022)“…Healthcare workers (HCWs) have experienced anxiety and psychological distress during the COVID-19 pandemic. We established and report findings from an…”
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Community SARS-CoV-2 seroprevalence before and after the second wave of SARS-CoV-2 infection in Harare, Zimbabwe
Published in EClinicalMedicine (01-11-2021)“…By the end of July 2021 Zimbabwe, has reported over 100,000 SARS-CoV-2 infections. The true number of SARS-CoV-2 infections is likely to be much higher. We…”
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Causes of acute hospitalization in adolescence: burden and spectrum of HIV-related morbidity in a country with an early-onset and severe HIV epidemic: a prospective survey
Published in PLoS medicine (01-02-2010)“…Survival to older childhood with untreated, vertically acquired HIV infection, which was previously considered extremely unusual, is increasingly well…”
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The transient effect of a peer support intervention to improve adherence among adolescents and young adults failing antiretroviral therapy in Harare, Zimbabwe: a randomized control trial
Published in AIDS research and therapy (16-06-2021)“…Abstract Background Adolescents and young adults living with HIV in sub Saharan Africa are at high risk of poor adherence to antiretroviral therapy (ART) and…”
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AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial
Published in Current controlled trials in cardiovascular medicine (23-11-2018)“…Cryptococcal meningitis (CM) is a major cause of mortality in HIV programmes in Africa despite increasing access to antiretroviral therapy (ART). Mortality is…”
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Diagnostic Accuracy of Point of Care Cryptococcal Antigen Lateral Flow Assay in Fingerprick Whole Blood and Urine Samples for the Detection of Asymptomatic Cryptococcal Disease in Patients with Advanced HIV Disease
Published in Microbiology spectrum (31-08-2022)“…Cryptococcal disease (CD) is a leading cause of mortality among individuals with advanced HIV disease (AHD). Screening with serum cryptococcal antigen (sCrAg)…”
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Prevalence of chronic conditions and multimorbidity among healthcare workers in Zimbabwe: Results from a screening intervention
Published in PLOS global public health (2024)“…The burden of non-communicable diseases (NCDs) in southern Africa is expanding and is superimposed on high HIV prevalence. Healthcare workers are a scarce…”
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Evaluation of a comprehensive health check offered to frontline health workers in Zimbabwe
Published in PLOS global public health (2024)“…Health workers are essential for a functioning healthcare system, and their own health is often not addressed. During the COVID-19 pandemic health workers were…”
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Exploring COVID-19 vaccine uptake among healthcare workers in Zimbabwe: A mixed methods study
Published in PLOS global public health (2023)“…With COVID-19 no longer categorized as a public health emergency of international concern, vaccination strategies and priority groups for vaccination have…”
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Access, attitudes and training in information technologies and evidence-based medicine among medical students at University of Zimbabwe College of Health Sciences
Published in African health sciences (01-09-2016)“…Background: The Medical Education Partnership Initiative, has helped to mitigate the digital divide in Africa. The aim of the study was to assess the level of…”
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Correction to: AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial
Published in Current controlled trials in cardiovascular medicine (14-01-2019)“…Following publication of the original article [1], we have been notified that one of the author names was listed incorrectly. Both incorrect and correct author…”
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Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal Meningitis
Published in The New England journal of medicine (24-03-2022)“…Cryptococcal meningitis is a major complication of HIV infection. In this phase 3, randomized, controlled trial in sub-Saharan Africa, a single dose of…”
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Diagnostic Accuracy of Pan-Degenerate Amplification and Adaptation Assay for HIV-1 Drug Resistance Mutation Analysis in Low- and Middle-Income Countries
Published in Journal of clinical microbiology (24-08-2020)“…HIV drug resistance (HIVDR) is a barrier to sustained virologic suppression in low- and middle-income countries (LMICs). Point mutation assays targeting…”
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