Search Results - "Nchinda, Godwin"
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Monkeypox Virus in Nigeria: Infection Biology, Epidemiology, and Evolution
Published in Viruses (05-11-2020)“…Monkeypox is a zoonotic disease caused by monkeypox virus (MPXV), which is a member of orthopoxvirus genus. The reemergence of MPXV in 2017 (at Bayelsa state)…”
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Evolutionary Qβ Phage Displayed Nanotag Library and Peptides for Biosensing
Published in Viruses (22-06-2023)“…We selected a novel biotin-binding peptide for sensing biotin, biotinylated proteins, and nucleotides. From a 15-mer library displayed on the RNA coliphage Qβ,…”
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microbial mimic poly IC induces durable and protective CD4⁺ T cell immunity together with a dendritic cell targeted vaccine
Published in Proceedings of the National Academy of Sciences - PNAS (19-02-2008)“…CD4⁺ Th1 type immunity is implicated in resistance to global infectious diseases. To improve the efficacy of T cell immunity induced by human immunodeficiency…”
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A cross-sectional study of acute dengue infection in paediatric clinics in Cameroon
Published in BMC public health (18-07-2019)“…Dengue fever is the world's fastest spreading mosquito borne viral infection. It is prevalent throughout both subtropical and tropical region, and affects over…”
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Regulatory T cells modulate monocyte functions in immunocompetent antiretroviral therapy naive HIV-1 infected people
Published in BMC immunology (14-10-2024)“…We previously demonstrated that the overall number of regulatory T (Treg) cells decrease proportionately with helper CD4 T cells and their frequencies increase…”
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Evaluation of a collaborative model for successful implementation of a National CD4 enumeration EQA program in Cameroon
Published in Scientific reports (02-06-2021)“…Participation in an EQA program is critical to the quality assurance process. Reliable and precise CD4 T-cells enumeration are essential to improve the…”
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Uniqueness of RNA Coliphage Qβ Display System in Directed Evolutionary Biotechnology
Published in Viruses (27-03-2021)“…Phage display technology involves the surface genetic engineering of phages to expose desirable proteins or peptides whose gene sequences are packaged within…”
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Global Assessment of Dengue Virus-Specific CD4 + T Cell Responses in Dengue-Endemic Areas
Published in Frontiers in immunology (13-10-2017)“…Dengue is a major public health problem worldwide. Assessment of adaptive immunity is important to understanding immunopathology and to define correlates of…”
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Toward the elimination of hepatitis B: networking to promote the prevention of vertical transmission of hepatitis B virus through population-based interventions and multidisciplinary groups in Africa
Published in Frontiers in public health (2024)“…The WHO African Region had 81 million people with chronic hepatitis B in 2019, which remains a silent killer. Hepatitis B virus (HBV), hepatitis delta virus…”
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Phenotypic characterization of regulatory T cells from antiretroviral‐naive HIV‐1‐infected people
Published in Immunology (01-08-2017)“…Summary Regulatory T (Treg) cells play a key role in dampening excessive immune activation. However, antiretroviral therapy (ART) ‐naive HIV‐1 infection…”
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Seroprevalence of dengue virus among children presenting with febrile illness in some public health facilities in Cameroon
Published in The Pan African medical journal (2018)“…A routine diagnosis of Dengue virus (DENV) infection is not usually conducted in hospitals. Because symptoms overlap, many potential febrile illnesses due to…”
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Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8⁺ T cells
Published in Proceedings of the National Academy of Sciences - PNAS (02-03-2010)“…To improve the efficacy of T cell-based vaccination, we pursued the principle that CD4⁺ T cells provide help for functional CD8⁺ T cell immunity. To do so, we…”
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Immunoglobulin G (IgG) specific responses to recombinant Qβ displayed MSP3 and UB05 in plasma of asymptomatic Plasmodium falciparum -infected children living in two different agro-ecological settings of Cameroon
Published in The Pan African medical journal (2024)“…in areas with intense perennial malaria transmission, limited data is available on the impact of environmental conditions especially rainfall on naturally…”
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Newcastle Disease Virus Expressing a Dendritic Cell-Targeted HIV Gag Protein Induces a Potent Gag-Specific Immune Response in Mice
Published in Journal of Virology (01-03-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Filaria specific antibody response profiling in plasma from anti-retroviral naïve Loa loa microfilaraemic HIV-1 infected people
Published in BMC infectious diseases (04-04-2018)“…In West and Central Africa areas of endemic Loa loa infections overlap with regions of high prevalence of human immunodeficiency virus type 1 (HIV-1)…”
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Performance of the BD FACSPresto near to patient analyzer in comparison with representative conventional CD4 instruments in Cameroon
Published in AIDS research and therapy (17-08-2020)“…Abstract Background In the context of scaling the viral load in resource limited settings, following HIV infected patient’s adults and children with CD4+…”
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Immunogenicity of DNA vaccines encoding simian immunodeficiency virus antigen targeted to dendritic cells in rhesus macaques
Published in PloS one (12-06-2012)“…Targeting antigens encoded by DNA vaccines to dendritic cells (DCs) in the presence of adjuvants enhances their immunogenicity and efficacy in mice. To explore…”
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Targeting the antigen encoded by adenoviral vectors to the DEC205 receptor modulates the cellular and humoral immune response
Published in International immunology (01-04-2013)“…Replication-defective adenoviral vectors have emerged as promising vaccine candidates for diseases relying on strong CD8(+) T-cell responses for protection. In…”
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Targeting antibody responses to the membrane proximal external region of the envelope glycoprotein of human immunodeficiency virus
Published in PloS one (30-05-2012)“…Although human immunodeficiency type 1 (HIV-1) infection induces strong antibody responses to the viral envelope glycoprotein (Env) only a few of these…”
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In vivo targeting of protein antigens to dendritic cells using anti‐DEC‐205 single chain antibody improves HIV Gag specific CD4+ T cell responses protecting from airway challenge with recombinant vaccinia‐gag virus
Published in Immunity, Inflammation and Disease (01-06-2019)“…Introduction Targeting antigens to dendritic cells (DCs) in vivo via a DC‐restricted endocytic receptor, DEC205, has been validated to enhance immunity in…”
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